The present invention revealed that the functional expression of hepatocyte growth factor (HGF) /HGF receptor is suppressed through the binding of the HGF receptor to a novel mucin-like protein, leading to the inhibition of HGF dependent cell proliferation and regeneration/neogenesis of tissues and blood vessels. Furthermore, inhibition of the binding between the HGF receptor and the mucin-like protein was found to enable treatment of various diseases including liver diseases.
                            本发明揭示了
肝细胞生长因子(
HGF)/
HGF 受体的功能表达可通过 
HGF 受体与一种新型粘蛋白样蛋白的结合而受到抑制,从而导致 
HGF 依赖性细胞增殖以及组织和血管的再生/新生受到抑制。此外,研究还发现,抑制 
HGF 受体与粘蛋白样蛋白之间的结合可以治疗包括肝脏疾病在内的各种疾病。