4-(4-bromorophenyl)-2,6-bis-(4-nitrophenyl)pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(4-bromorophenyl)-2,6-bis-(4-nitrophenyl)pyridine
• 英文别名: 4-(4-Bromophenyl)-2,6-bis(4-nitrophenyl)pyridine
• 化学式: C₂₃H₁₄BrN₃O₄
• 分子量: 476.286
• InChiKey: OTPXVCWUSUOHSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-(4-bromorophenyl)-2,6-bis-(4-nitrophenyl)pyridine 在 tin(II) chloride dihdyrate 作用下， 以 乙酸乙酯 为溶剂， 反应 24.0h， 以60%的产率得到4-[6-(4-Aminophenyl)-4-(4-bromophenyl)pyridin-2-yl]aniline
  参考文献：
  名称：

  二硝单体、二胺单体、聚酰亚胺以及经改质的 聚酰亚胺

  摘要：

  本发明提供一种二硝单体、一种二胺单体、一种聚酰亚胺以及一种该经改质的聚酰亚胺。聚酰亚胺包括式III所示的结构：式III其中X为卤素，A1选自式1至式18的任一者，n为2至500，

  公开号：

  CN103896829B
• 作为产物：
  描述：

  对溴苯甲醛 、 对硝基苯乙酮 在 ammonium acetate 、 溶剂黄146 作用下， 反应 24.0h， 以45%的产率得到4-(4-bromorophenyl)-2,6-bis-(4-nitrophenyl)pyridine
  参考文献：
  名称：

  二硝单体、二胺单体、聚酰亚胺以及经改质的 聚酰亚胺

  摘要：

  本发明提供一种二硝单体、一种二胺单体、一种聚酰亚胺以及一种该经改质的聚酰亚胺。聚酰亚胺包括式III所示的结构：式III其中X为卤素，A1选自式1至式18的任一者，n为2至500，

  公开号：

  CN103896829B

文献信息

• An Efficient Synthesis of 2,4,6-Triarylpyridines via Solvent-Free Reaction between Acetophenoneoximes and Aldehydes
  作者：Mehdi Adib、Shabnam Mahernia、Mohammad Mahdavi

  DOI：10.1055/s-0033-1341109

  日期：——

  An efficient synthesis of 2,4,6-triarylpyridines is described. Heating a mixture of an acetophenoneoxime and an aldehyde under solvent-free conditions afforded Krohnke pyridines in excellent yields. In this method acetophenoneoximes are directly used for the preparation of Krohnke pyridines under metal-free conditions.

  描述了 2,4,6-三芳基吡啶的有效合成。在无溶剂条件下加热苯乙酮​​肟和醛的混合物以优异的产率提供克罗恩克吡啶。在该方法中，苯乙酮肟直接用于在无金属条件下制备克罗恩克吡啶。
• A solvent-free reaction between acetophenone oximes and epoxy styrenes: an efficient synthesis of 2,4,6-triarylpyridines under neutral conditions
  作者：Shabnam Mahernia、Mehdi Adib、Mohammad Mahdavi、Meisam Nosrati

  DOI：10.1016/j.tetlet.2014.04.003

  日期：2014.7

  An efficient synthesis of 2,4,6-triarylpyridines is described which involves heating a mixture of an acetophenone oxime and an epoxy styrene under neutral, solvent-free conditions. Krohnke pyridine products are obtained in excellent yields. (C) 2014 Published by Elsevier Ltd.
• Novel solid-supported dimerization–heteroannulation of chalcones: simple and efficient synthesis of 2,4,6-triaryl-3-methylarylpyridines
  作者：Anil K. Verma、Summon Koul、Ajay P.S. Pannu、Tej K. Razdan

  DOI：10.1016/j.tet.2007.06.049

  日期：2007.9

  2,4,6-Triaryl-3-methylarylpyridines were obtained, in 60-70% yield, by a novel one-pot solventless solid-supported dimerization-heteroannulation reaction of chalcones and compounds possessing terminal -CONH2 functionality, at 125-135 degrees C, using immobilized Bi(III) nitrate and Zn(II) chloride as co-catalyst. Initially, chalcones were prepared, in nearly quantitative yield, by a modified aldol condensation, in neutral aqueous medium, in the presence of p-toluenesodium sulfonate. (c) 2007 Elsevier Ltd. All rights reserved.
• Kröhnke reaction in aqueous media: one-pot clean synthesis of 4′-aryl-2,2′:6′,2″-terpyridines
  作者：Shujiang Tu、Runhong Jia、Bo Jiang、Junyong Zhang、Yan Zhang、Changsheng Yao、Shunjun Ji

  DOI：10.1016/j.tet.2006.10.069

  日期：2007.1

  A clean aqueous Krohnke reaction process has been accomplished via a one-pot procedure of 2-acetylpyridine with aromatic aldehyde and ammonium acetate under microwave irradiation or conventional heating conditions. This method is convenient, economic and environmental friendly. (c) 2006 Elsevier Ltd. All rights reserved.
• DINITRO MONOMER, DIAMINE MONOMER, POLYIMIDE AND MODIFIED POLYIMIDE
  申请人：TAIWAN TEXTILE RESEARCH INSTITUTE

  公开号：US20140179878A1

  公开（公告）日：2014-06-26

  A polyimide including a structure shown as Formula II is provided, wherein X is halogen, A 1 is selected from one of Formula 1 to Formula 18, and n is from 2 to 500,