1-[2'-chloro-6'-fluoro-4'-trifluoromethylphenyl]-4-methoxyindole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1-[2'-chloro-6'-fluoro-4'-trifluoromethylphenyl]-4-methoxyindole
• 英文别名: 1-[2-Chloro-6-fluoro-4-(trifluoromethyl)phenyl]-4-methoxyindole
• 化学式: C₁₆H₁₀ClF₄NO
• 分子量: 343.708
• InChiKey: DIVAOFLJRVRLAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  14.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-甲氧基吲哚 、 3-氯-4,5-二氟三氟甲苯 以 甲醇 、 二甲基亚砜 为溶剂， 生成 1-[2'-chloro-6'-fluoro-4'-trifluoromethylphenyl]-4-methoxyindole
  参考文献：
  名称：

  N-arylindoles and their use as herbicides

  摘要：

  N-芳基吲哚的替代物，生产它们的方法以及它们作为除草剂的用途。具体来说，在以下公式中披霭的N-芳基吲哚被披露，其中：R为氢；卤素；硝基；氰基；烷基；烷氧基；烯基氧基；炔基氧基；烷氧基烷基；羰基烷氧基；烷氧基烷氧基；氰基烷氧基；苄氧基；烷氧羰基烷氧基；烷基羰基烷氧基；卤基烷基；羟基烷基；甲酰基；叠氮基；羧基或其盐；COO烷基；氨基；取代氨基，其中取代基为烷基、烷氧基、羟基、甲酰基、取代烷基羰基，取代基与羧基或烷氧基羧基取代的烷基磺酰基、卤基烷磺酰基、氨基羰基、（二）烷基氨基羰基、烷氧羰基、烷氧基烷基、羟基羰基烷基、烷氧羰基烷基、氨基或（二）烷基氨基；羧基酰胺；取代羧基酰胺，其中所述取代基可以选择自烷基、烷磺酰基和卤基烷磺酰基；磺酰胺，其中N被氢和/或烷基取代；YR.sup.4，其中Y为O或S(O).sub.m，R.sup.4选自群氢、烷基、卤基烷基、氰基烷基、烷氧基羰基、羟基羰基烷基和氨基羰基烷基，其中N被氢和/或烷基取代；n为0至4，m为0至2；R.sup.1为氢、烷基、卤素、氰基、卤基烷基、烷氧基或羧基或其盐或酯；q为0至2；X为氢、卤素、氰基、硝基、烷硫基、烷亚硫基、烷磺基或烷氧基；k为0至2；Z为N或C-R.sup.2；其中R.sup.2为氢、卤素、卤基烷基、氰基、硝基、烷硫基、烷亚硫基、烷磺基或烷氧基；R.sup.3为氢、卤基烷基、卤基烷氧基、氰基、卤素或SO.sub.y R.sup.5，其中R.sup.5为烷基或卤基烷基，y为0、1或2；以及其农业可接受的盐。

  公开号：

  US05599774A1

文献信息

• N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES
  申请人：Pallos, Ferenc M.

  公开号：EP0626946A1

  公开（公告）日：1994-12-07
• US5395817A
  申请人：——

  公开号：US5395817A

  公开（公告）日：1995-03-07
• US5599774A
  申请人：——

  公开号：US5599774A

  公开（公告）日：1997-02-04
• [EN] N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES
  申请人：ZENECA LIMITED

  公开号：WO1993015049A1

  公开（公告）日：1993-08-05

  (EN) This invention relates to substituted N-arylindoles, a process for producing them and their use as herbicides. In particular, this invention relates to substituted N-arylindoles of formula (I) in which R is hydrogen; halogen; nitro; cyano; alkyl; alkoxy; alkenyloxy; alkynyloxy; alkoxyalkyl; carbonylalkoxy; alkyloxyalkoxy; cyanoalkoxy; benzyloxy; alkoxycarbonylalkoxy; alkylcarbonylalkoxy; haloalkyl; hydroxalkyl; formyl; azido; carboxy and its salts; COOalkyl; amino; substituted amino wherein the substituents are alkyl, alkoxy, hydroxy, formyl, alkylcarbonyl, substituted alkylcarbonyl substituted with carboxy or alkoxycarboxy, alkylsulfonyl, haloalkylsulfonyl, aminocarbonyl, (di)alkylaminocarbonyl, alkoxycarbonyl, alkoxyalkyl, hydroxycarbonylalkyl, alkoxycarbonylalkyl, amino and (di)alkyl amino; carboxyamido; substituted carboxyamide wherein said substituents can be selected from alkyl, alkylsulfonyl, and haloalkylsulfonyl; sulfonamido wherein the N is substituted with hydrogen and/or alkyl; YR4 wherein Y is O and S(O)m and R4 is selected from the group hydrogen, alkyl, haloalkyl, cyanoalkyl, alkoxycarbonylalkyl, hydroxycarbonylalkyl and aminocarbonylalkyl wherein the N is substituted with hydrogen and/or alkyl; n is 0 to 4 and m is 0 to 2; R1 is hydrogen, alkyl, halogen, cyano, haloalkyl, alkoxy, and carboxy and its salts or esters; q is 0 to 2; X is hydrogen, halogen, cyano, nitro, alkylthio, alkylsulfinyl, alkylsulfonyl, and alkoxy; k is 0 to 2; Z is N and C-R2; wherein R2 is hydrogen, halogen, haloalkyl, cyano, nitro, alkylthio, alkylsulfinyl, alkylsulfonyl and alkoxy; R3 is hydrogen, haloalkyl, haloalkoxy, cyano, halogen, and SOyR5 wherein R5 is alkyl or haloalkyl and y is 0, 1 or 2; and agriculturally acceptable salts thereof.(FR) L'invention se rapporte à des N-arylindoles substitués, à leur procédé de fabrication et à leur utilisation comme herbicides. L'invention se rapporte notamment à des N-arylindoles substitués de la formule (I) dans laquelle R représente hydrogène; halogène; nitro; cyano; alkyle; alcoxy; alcényloxy; alkynyloxy; alcoxyalkyle; carbonylalcoxy; alkyloxyalcoxy; cyanoalcoxy; benzyloxy; alcoxycarbonylalcoxy; alkylcarbonylalcoxy; haloalkyle; hydroxalkyle; formyle; azido; carboxy et ses sels; COOalkyle; amino; amino substitué dans lequel les substituants représentent alkyle, alcoxy, hydroxy, formyle, alkylacarbonyle, alkylcarbonyle, substitué par carboxy ou alcoxycarboxy, alkylsulfonyle, haloalkylsulfonyle, aminocarbonyle, (di)alkylaminocarbonyle, alcoxycarbonyle, alcoxyalkyle, hydroxycarbonylalkyle, alcoxycarbonylalkyle, amino et (di)alkyle amino; carboxyamido; carboxyamide substitué dans lequel lesdits substituants peuvent être sélectionnés parmi alkyle, alkylsulfonyle, et haloalkylsulfonyle; sulfonamido dans lequel N est substitué par hydrogène et/ou alkyle; YR4 dans lequel Y représente O et S(O)m et R4 est sélectionné parmi le groupe hydrogène, alkyle, haloalkyle, cyanoalkyle, alcoxycarbonylalkyle, hydroxycarbonylalkyle et aminocarbonylalkyle dans lequel N est substitué par hydrogène et/ou alkyle; n est 0 à 4 et m est 0 à 2; R1 représente hydrogène, alkyle, halogène, cyano, haloalkyle, alcoxy, et carboxy et ses sels ou esters; q est 0 à 2; X représente hydrogène, halogène, cyano, nitro, alkylthio, alkylsulfinyle, alkylsulfonyle, et alcoxy; k est 0 à 2; Z représente N et C-R2, dans lequel R2 représente hydrogène, halogène, haloalkyle, cyano, nitro, alkylthio, alkylsulfinyle, alkylsulfonyle et alcoxy; R3 représente hydrogène, haloalkyle, haloalcoxy, cyano, halogène et SOyR5 dans lequel R5 représente alkyle ou haloalkyle et y est 0, 1 ou 2; et des sels acceptables en agriculture.
• N-arylindoles and their use as herbicides
  申请人：Imperial Chemical Industries PLC

  公开号：US05395817A1

  公开（公告）日：1995-03-07

  Substituted N-arylindoles, a process for producing them and their use as herbicides. In particular, substituted N-arylindoles of the formula ##STR1## are disclosed in which: R is hydrogen; halogen; nitro; cyano; alkyl; alkoxy; alkenyloxy; alkynyloxy; alkoxyalkyl; carbonylalkoxy; alkyloxyalkoxy; cyanoalkoxy; benzyloxy; alkoxycarbonylalkoxy; alkylcarbonylalkoxy; haloalkyl; hydroxyalkyl; formyl; azido; carboxy or a salt thereof; amino; substituted amino; carboxyamido; substituted carboxyamido; sulfonamido wherein the N is substituted with hydrogen and/or alkyl; or YR.sup.4 wherein Y is O or S(O).sub.m and R.sup.4 is hydrogen, alkyl, haloalkyl, cyanoalkyl, alkoxycarbonylalkyl, hydroxycarbonylalkyl or aminocarbonylalkyl; R.sup.1 is hydrogen, alkyl, halogen, cyano, haloalkyl, alkoxy, or carboxy or a salt thereof; X is hydrogen, halogen, cyano, nitro, alkylthio, alkylsulfinyl, alkylsulfonyl, haloalkyl or alkoxy; R.sup.3 is hydrogen, haloalkyl, haloalkoxy, cyano, halogen, or SO.sub.y R.sup.5 wherein R.sup.5 is alkyl or haloalkyl.

  取代N-芳基吲哚，一种生产它们的过程以及它们作为除草剂的用途。具体地，公开了公式##STR1##中的取代N-芳基吲哚，其中：R为氢；卤素；硝基；氰基；烷基；烷氧基；烯烷氧基；炔烷氧基；烷氧基烷基；羰基烷氧基；烷氧基烷氧基；氰基烷氧基；苄氧基；烷氧基羰基烷氧基；烷基羰基烷氧基；卤代烷基；羟基烷基；甲酰基；叠氮基；羧基或其盐；氨基；取代氨基；羧胺基；取代羧胺基；磺酰胺基，其中N被氢和/或烷基取代；或YR.sup.4，其中Y为O或S(O).sub.m，R.sup.4为氢、烷基、卤代烷基、氰基烷基、烷氧羰基烷基、羟基羰基烷基或氨基羰基烷基；R.sup.1为氢、烷基、卤素、氰基、卤代烷基、烷氧基或其盐；X为氢、卤素、氰基、硝基、烷硫基、烷硫醇基、烷磺酰基、卤代烷基或烷氧基；R.sup.3为氢、卤代烷基、卤代烷氧基、氰基、卤素或SO.sub.y R.sup.5，其中R.sup.5为烷基或卤代烷基。