5,10-diphenyltetrahydropyrrolo[3,4-c]pyrrolo[3',4':4,5]pyrazolo[1,2-a]pyrazole-1,3,6,8(2H,3aH,5H,7H)-tetrone | 201536-05-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5,10-diphenyltetrahydropyrrolo[3,4-c]pyrrolo[3',4':4,5]pyrazolo[1,2-a]pyrazole-1,3,6,8(2H,3aH,5H,7H)-tetrone
• 英文别名: 7,14-diphenyl-1,4,8,11-tetrazatetracyclo[6.6.0.02,6.09,13]tetradecane-3,5,10,12-tetrone
• CAS: 201536-05-2
• 化学式: C₂₂H₁₈N₄O₄
• 分子量: 402.409
• InChiKey: ZGOMYWGKPKIJLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  30
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  98.8
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  5,10-diphenyltetrahydropyrrolo[3,4-c]pyrrolo[3',4':4,5]pyrazolo[1,2-a]pyrazole-1,3,6,8(2H,3aH,5H,7H)-tetrone 在 氯磺酸 、 氯化亚砜 作用下， 以 甲醇 为溶剂， 反应 174.0h， 生成 4-[14-[4-(diethylsulfamoyl)phenyl]-3,5,10,12-tetraoxo-1,4,8,11-tetrazatetracyclo[6.6.0.02,6.09,13]tetradecan-7-yl]-N,N-diethylbenzenesulfonamide
  参考文献：
  名称：

  SOME SULFONYL CRISSCROSS CYCLOADDUCTS

  摘要：

  The dipolar cycloadducts from diaryl azines and maleimides ((1) under bar, <(20)under bar>) or maleic anhydride (<(18)under bar>) have been reacted with chlorosulfonic acid to give the bis- ((2) under bar, <(19)under bar>) or tetrachlorosulfonyl derivatives (<(21)under bar>). The chorosulfonation generally required addition of thionyl chloride. The various sulfonyl chlorides were converted into a range of sulfonamides ((3) under bar-<(11)under bar>, <(13)under bar>-<(16)under bar>) and the N-butylsulfamate (<(12)under bar>). The N,N-dialkylsulfamonyl cycloadducts (<(23)under bar>, <(25)under bar>) were also obtained by cycloaddition of the bis-dimethylsulfamoyl 2-methoxybenzaldehyde azine (<(22)under bar>) and N-phenyl maleimide or the N-((p) under bar-diethylsulfamoylphenyl) maleimide (<(24)under bar>) with (p) under bar-tolualdehyde azine, although the former reaction did not go to completion.Attempts to carry out the cycloaddition between the two sulfamoyl reactants (<(22)under bar> and <(24)under bar>) were unsuccessful. The various sulfonamide derivatives will be screened as pesticides.

  DOI：

  10.1080/10426509708043497
• 作为产物：
  描述：

  马来酰亚胺 、 苯甲醛吖嗪 以 xylene 为溶剂， 反应 18.0h， 以91%的产率得到5,10-diphenyltetrahydropyrrolo[3,4-c]pyrrolo[3',4':4,5]pyrazolo[1,2-a]pyrazole-1,3,6,8(2H,3aH,5H,7H)-tetrone
  参考文献：
  名称：

  SOME SULFONYL CRISSCROSS CYCLOADDUCTS

  摘要：

  The dipolar cycloadducts from diaryl azines and maleimides ((1) under bar, <(20)under bar>) or maleic anhydride (<(18)under bar>) have been reacted with chlorosulfonic acid to give the bis- ((2) under bar, <(19)under bar>) or tetrachlorosulfonyl derivatives (<(21)under bar>). The chorosulfonation generally required addition of thionyl chloride. The various sulfonyl chlorides were converted into a range of sulfonamides ((3) under bar-<(11)under bar>, <(13)under bar>-<(16)under bar>) and the N-butylsulfamate (<(12)under bar>). The N,N-dialkylsulfamonyl cycloadducts (<(23)under bar>, <(25)under bar>) were also obtained by cycloaddition of the bis-dimethylsulfamoyl 2-methoxybenzaldehyde azine (<(22)under bar>) and N-phenyl maleimide or the N-((p) under bar-diethylsulfamoylphenyl) maleimide (<(24)under bar>) with (p) under bar-tolualdehyde azine, although the former reaction did not go to completion.Attempts to carry out the cycloaddition between the two sulfamoyl reactants (<(22)under bar> and <(24)under bar>) were unsuccessful. The various sulfonamide derivatives will be screened as pesticides.

  DOI：

  10.1080/10426509708043497

文献信息

• SOME SULFONYL CRISSCROSS CYCLOADDUCTS
  作者：Richard J. Cremlyn、Richard M. Ellam、Sultan Farouk、Stephen Graham、Anthony Williams

  DOI：10.1080/10426509708043497

  日期：1997.3.1

  The dipolar cycloadducts from diaryl azines and maleimides ((1) under bar, <(20)under bar>) or maleic anhydride (<(18)under bar>) have been reacted with chlorosulfonic acid to give the bis- ((2) under bar, <(19)under bar>) or tetrachlorosulfonyl derivatives (<(21)under bar>). The chorosulfonation generally required addition of thionyl chloride. The various sulfonyl chlorides were converted into a range of sulfonamides ((3) under bar-<(11)under bar>, <(13)under bar>-<(16)under bar>) and the N-butylsulfamate (<(12)under bar>). The N,N-dialkylsulfamonyl cycloadducts (<(23)under bar>, <(25)under bar>) were also obtained by cycloaddition of the bis-dimethylsulfamoyl 2-methoxybenzaldehyde azine (<(22)under bar>) and N-phenyl maleimide or the N-((p) under bar-diethylsulfamoylphenyl) maleimide (<(24)under bar>) with (p) under bar-tolualdehyde azine, although the former reaction did not go to completion.Attempts to carry out the cycloaddition between the two sulfamoyl reactants (<(22)under bar> and <(24)under bar>) were unsuccessful. The various sulfonamide derivatives will be screened as pesticides.