5,6-dihydro-7-methyl-7H-benzocarbazole | 54903-06-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5,6-dihydro-7-methyl-7H-benzocarbazole
• 英文别名: 5-methyl-6,7-dihydro-5H-benzocarbazole；5-methyl-6,7-dihydrobenzocarbazole；N-methyl-5,6-dihydrobenzocarbazole；7-methyl-6,7-dihydro-5H-benzo[c]carbazole；7-Methyl-5,6-dihydrobenzo[c]carbazole
• CAS: 54903-06-9
• 化学式: C₁₇H₁₅N
• 分子量: 233.313
• InChiKey: UHHCQVVLBQNXKJ-UHFFFAOYSA-N

物化性质

• 熔点：
  133.5 °C(Solv: ligroine (8032-32-4))
• 沸点：
  423.5±14.0 °C(Predicted)
• 密度：
  1.15±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  4.9
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  5,6-dihydro-7-methyl-7H-benzocarbazole 生成 7-methyl-7H-benzo[c]carbazole
  参考文献：
  名称：

  Reactivity and decay pathways of photoexcited anilinonaphthalenes

  摘要：

  DOI：

  10.1021/ja00387a018
• 作为产物：
  描述：

  2-[甲基(苯基)氨基]-3,4-二氢萘-1-酮 以 溶剂黄146 为溶剂， 反应 3.0h， 以0.6%的产率得到5,6-dihydro-7-methyl-7H-benzocarbazole
  参考文献：
  名称：

  Allworth, Keith L.; EI-Hamamy, Ahmad A.; Hesabi, Massoud M., Journal of the Chemical Society. Perkin transactions I, 1980, p. 1671 - 1678

  摘要：

  DOI：

文献信息

• Three‐Component Difunctionalization of Cyclohexenyl Triflates: Direct Access to Versatile Cyclohexenes via Cyclohexynes
  作者：Seoyoung Cho、E. J. McLaren、Qiu Wang

  DOI：10.1002/anie.202109482

  日期：2021.12.6

  dicarbofunctionalization, aminohalogenation and aminocarbonation of readily available cyclohexenyl triflates, via strained cyclic alkyne intermediates generated in situ. The importance and utility of this method is exemplified by the modularity of this approach and the ease in which even highly complex polycyclic scaffolds can be accessed in one step.

  我们报告了一种有效且灵活的方法，通过原位生成的应变环炔中间体，实现易于获得的环己烯基三氟甲磺酸酯的碳卤化、双碳功能化、氨基卤化和氨基碳化。这种方法的重要性和实用性体现在这种方法的模块化以及即使高度复杂的多环支架也可以一步访问的容易性。
• Radical cyclisation reactions with indoles
  作者：Stuart R. Flanagan、David C. Harrowven、Mark Bradley

  DOI：10.1016/s0040-4039(03)00094-7

  日期：2003.2

  Several radical cyclisation reactions involving indoles are described. Most notably, we have shown that radical additions to C3 of an indole are frequently facile. A dichotomy in the course of radical cyclisation reactions to C2 of the indole has also been exposed wherein 6-endo-trig cyclisations are propagated by the loss of a hydrogen atom from C2 while 5-exo-trig cyclisations are propagated by hydrogen

  描述了涉及吲哚的几种自由基环化反应。最值得注意的是，我们已经表明，将吲哚的C3自由基加成通常很容易。还公开了对吲哚的C 2进行自由基环化反应的二分法，其中6-内-trig环化通过氢原子从C2的损失而传播，而5- exo- trig环化通过氢原子的抽象而传播。由氢化三丁基锡得到的C3。还已经证明了涉及向吲哚中添加吲哚基自由基中间体的环化。
• NOVEL COMPOUND
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP3196187A1

  公开（公告）日：2017-07-26

  A compound is represented by the following formula (1). In the formula (1), Ar is a substituted or unsubstituted aryl group including 6 to 30 ring carbon atoms, Ra are independently a substituted or unsubstituted alkyl group including 1 to 15 carbon atoms, or a substituted or unsubstituted cycloalkyl group including 3 to 15 carbon atoms, Rb1 to Rb4 are independently a halogen atom, a cyano group, a substituted or unsubstituted alkyl group including 1 to 15 carbon atoms, or the like, Rc1 to Rc10 are independently a hydrogen atom, a halogen atom, a cyano group, a substituted or unsubstituted alkyl group including 1 to 15 carbon atoms, or the like, * is a bonding position at which one of Rc1 to Rc10 is bonded to either nitrogen atom, x is an integer from 0 to 3, y is an integer from 0 to 4, and z are independently an integer from 0 to 5.

  一种化合物由下式（1）表示。在式 (1) 中，Ar 是包括 6 至 30 个环碳原子的取代或未取代的芳基；Ra 独立地是包括 1 至 15 个碳原子的取代或未取代的烷基，或包括 3 至 15 个碳原子的取代或未取代的环烷基；Rb1 至 Rb4 独立地是卤素原子、氰基、包括 1 至 15 个碳原子的取代或未取代的烷基、或类似物，Rc1 至 Rc10 独立地为氢原子、卤素原子、氰基、包括 1 至 15 个碳原子的取代或未取代的烷基，* 为 Rc1 至 Rc10 之一与任一氮原子键合的键位，x 为 0 至 3 的整数，y 为 0 至 4 的整数，z 独立地为 0 至 5 的整数。
• Letcher, Roy M.; Choi, Michael C. K.; Wai, John S. M., Journal of Chemical Research, Miniprint, 1987, # 10, p. 2629 - 2659
  作者：Letcher, Roy M.、Choi, Michael C. K.、Wai, John S. M.

  DOI：——

  日期：——
• ALLWORTH K. L.; EL-HAMAMY A. A.; HESABI M. M.; HILL J., J. CHEM. SOC. PERKIN TRANS., PART 1, 1980, NO 8, 2671-2678
  作者：ALLWORTH K. L.、 EL-HAMAMY A. A.、 HESABI M. M.、 HILL J.

  DOI：——

  日期：——