(E)-2-(4-N,N-dimethylaminostyryl)-3,3-dimethyl-3H-indole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (E)-2-(4-N,N-dimethylaminostyryl)-3,3-dimethyl-3H-indole
• 英文别名: Azj-1-B；3H-Indole, 3,3-dimethyl-2-[2-(4-dimethylaminophenyl)ethenyl]-；4-[(E)-2-(3,3-dimethylindol-2-yl)ethenyl]-N,N-dimethylaniline
• 化学式: C₂₀H₂₂N₂
• 分子量: 290.408
• InChiKey: SXGAOGLBVSAZEI-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  spiro[2-cyclopropene-1,9'-fluorene]-2,3-dimethyldicarboxylate 、 (E)-2-(4-N,N-dimethylaminostyryl)-3,3-dimethyl-3H-indole 以 乙醚 为溶剂， 以80%的产率得到2',3'-di(methoxycarbonyl)-7',7'-dimethyl-5'-(4-dimethylaminophenyl)spirofluorene-9,4'-(1-aza-2,6-cycloheptadieno)[1,7-a]indoline
  参考文献：
  名称：

  A Simple Access to Indolino-Azepines - A New Halochromic System for Information Recording

  摘要：

  报告了一种新的 8Ï- 系统的全选择性反应。该体系是通过螺[2-环丙烯-1,9Ž-芴]-2,3-二甲基二甲酸酯 2 与 2-苯乙烯基-3H-吲哚 1 反应制备的，反应生成氮杂卓衍生物 4。向 4 中加入酸会导致重要的颜色变化，从而产生一种新的卤色系统。

  DOI：

  10.1055/s-2001-17528
• 作为产物：
  描述：

  2,3,3-三甲基-3H-吲哚 、 对二甲氨基苯甲醛 在 盐酸 作用下， 以 水 、 乙醇 为溶剂， 反应 4.5h， 以78.4%的产率得到(E)-2-(4-N,N-dimethylaminostyryl)-3,3-dimethyl-3H-indole
  参考文献：
  名称：

  Elaboration of thorough simplified vinca alkaloids as antimitotic agents based on pharmacophore similarity

  摘要：

  Thorough simplification of vinca alkaloids based on pharmacophore similarity has been conducted. A concise process for the syntheses of target compounds was successfully developed with yields from poor to excellent (19-98%). Cell growth inhibitory activities of these synthesized compounds were evaluated in five cancer cell lines including MCF-7, MDA-MB-231, HepG2, HepG2/ADM and K562. Almost all compounds exhibited moderate antitumor activity with optimal IC50 value of 0.89 +/- 0.07 mu M in MCF-7 cells. Investigation of structure-activity relationship (SAR) indicates that electron-withdraw substituents on the ring contribute to the enhancement of the antitumor activities. The simplified vinca alkaloids are confirmed as antimitotic agents, which inhibit the polymerization of tubulin just like vinblastine. (C) 2013 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2013.04.057

文献信息

• Photosensitive resin composition and photosensitive films and laminates made by using the same
  申请人：——

  公开号：US20040265731A1

  公开（公告）日：2004-12-30

  A photosensitive resin composition of the present invention contains a (A) soluble polyimide and a (b) (meth)acrylic compound, the (A) soluble polyimide being soluble in an organic solvent and being synthesized by using an acid dianhydride component and at least one of a diamine component containing a siloxane structure or an aromatic ring structure, and a diamine component having, in its structure, a hydroxyl group a carboxyl group or a carbonyl group, and the (B) (meth)acrylic compound having at least one carbon-carbon double bond, and preferably contains at least one of a (C) photo reaction initiator and a (D) fire retardant. With this arrangement, the photosensitive resin composition of the present invention is capable of having excellent properties. Especially, the photosensitive resin composition of the present invention is so excellently useful that it can be used for electronic parts and the like.

  本发明的光敏树脂组合物包含(A)可溶性聚酰亚胺和(b)(甲基)丙烯酸化合物，其中(A)可溶性聚酰亚胺可在有机溶剂中溶解，并通过使用酸性二酐组分和至少一种含有硅氧烷结构或芳香环结构的二胺组分以及结构中具有羟基、羧基或羰基的二胺组分合成，(B)(甲基)丙烯酸化合物具有至少一个碳-碳双键，并且最好包含至少一个(C)光反应引发剂和(D)阻燃剂。通过这种安排，本发明的光敏树脂组合物具有优异的性能。特别是，本发明的光敏树脂组合物非常有用，可以用于电子零件等。
• Diamine, acid dianhydride, polymide composition having reactive group obtained therefrom, and processes for producing these
  申请人：——

  公开号：US20040158030A1

  公开（公告）日：2004-08-12

  The present invention relates to a novel diamine, a novel acid dianhydride, and a novel composition containing a polyimide produced from such diamine and acid dianhydride. Specifically, the present invention relates to an acid dianhydride that has a photosensitive group bonded through the mediation of an alkylene group or a fluoroalkylene group, a diamine that has a reactive group bonded through the mediation of an alkylene group or a fluoroalkylene group, and a polyimide composition that contains a novel polyimide having at least one of such acid dianhydride residue and diamine residue in a molecule thereof. Particularly, an object of the present invention is to provide a novel polyimide that has both photoreactivity and thermoreactivity specific to the reactive group and whose reactive group is selected from the group consisting of: organic groups derived from cinnamic acid, chalcone, furylacryloyl, benzalacetophenone, stilbene, coumarin, and pyrone; allyl; propargyl; ethinyl; CH 2 ═CH—; CH 2 ═C(CH 3 )—; and skeletons derived therefrom, and it to provide a novel diamine and a novel acid dianhydride that may be contained in the polyimide composition.

  本发明涉及一种新的二胺、一种新的酸二酐和一种含有由此类二胺和酸二酐制备的聚酰亚胺的新组合物。具体地，本发明涉及一种通过烷基或氟烷基介导的光敏基团键合的酸二酐，一种通过烷基或氟烷基介导的反应性基团键合的二胺，以及一种聚酰亚胺组合物，其分子中含有至少一个这样的酸二酐残基和二胺残基。特别地，本发明的目的是提供一种具有光反应性和热反应性的新型聚酰亚胺，其反应性基团来自以下群组：来自肉桂酸、查尔酮、呋喃丙烯酰、苯甲酰乙酮、亚苯基烯、香豆素和吡喃的有机基团；烯丙基；丙炔基；乙炔基；CH2═CH—； ═C(CH3)—；以及派生自这些基团的骨架，并提供可包含在聚酰亚胺组合物中的新型二胺和新型酸二酐。
• Polyimide dry film and application thereof
  申请人：ETERNAL MATERIALS CO., LTD.

  公开号：US10590305B2

  公开（公告）日：2020-03-17

  A polyimide dry film including a carrier and a polyimide layer and a method of using the same are provided. The polyimide layer contains (a) a polyimide precursor or soluble polyimide and (b) a solvent. The solvent includes a hydrophilic solvent and a hydrophobic solvent and a weight ratio of the hydrophilic solvent to the hydrophobic solvent is in the range of about 0.05 to about 2. The polyimide dry film of the present invention has water absorbability, is relatively stable even in the presence of water, and has a non-sticky surface. The resulting polyimide has excellent physical properties and can be used in a process in which water or an aqueous solution is involved to form a coverlay with excellent physical properties.

  提供了一种包括载体和聚酰亚胺层的聚酰亚胺干膜及其使用方法。聚酰亚胺层包含 (a) 聚酰亚胺前体或可溶性聚酰亚胺和 (b) 溶剂。溶剂包括亲水性溶剂和疏水性溶剂，亲水性溶剂与疏水性溶剂的重量比在约 0.05 至约 2 之间。本发明的聚酰亚胺干膜具有吸水性，即使在有水的情况下也相对稳定，并且表面不粘。得到的聚酰亚胺具有优异的物理性能，可用于涉及水或水溶液的工艺中，形成物理性能优异的覆盖层。
• Solvent-containing dry film and method for applying the same on a substrate
  申请人：ETERNAL MATERIALS CO., LTD.

  公开号：US10639876B2

  公开（公告）日：2020-05-05

  The present disclosure relates to a solvent-containing dry film and a method for applying a dry film on a substrate. The dry film includes a carrier and a resin layer. The resin layer contains a resin composition and a solvent and the solvent is present in a total amount of at least 5 wt % based on the total weight of the resin layer. The dry film of the present invention can be applied onto a substrate without the use of a prior art vacuum lamination apparatus. The application process is simple and is more cost-efficient than the prior art techniques.

  本公开涉及一种含溶剂的干膜和一种在基底上涂敷干膜的方法。干膜包括载体和树脂层。树脂层含有树脂组合物和溶剂，溶剂的总量至少占树脂层总重量的 5%。本发明的干膜无需使用现有技术中的真空层压设备即可涂覆在基底上。与现有技术相比，本发明的应用过程简单，成本效益更高。
• Epoxy-modified polyimide, photosensitive composition, coverlay film, solder resist, and printed wiring board using the epoxy-modified polyimide
  申请人：——

  公开号：US20010056174A1

  公开（公告）日：2001-12-27

  An object of the present invention is to provide an epoxy modified polyimide, which is a resin capable of treating at a low processing temperature and having an excellent heat resistance; photosensitive composition; coverlay film, which is excellent in electrical insulation property, heat resistance for soldering, film-formability, flexibility, and chemical resistance; solder resist; and printed wiring board. The epoxy modified polyimide is obtained by synthesizing polyimide having a hydroxy group or carboxy group and subsequently reacting the polyimide with an epoxy compound. The photosensitive composition is obtained by adding a photoreaction initiator or the like to the epoxy modified polyimide. The coverlay film and the solder resist can be formed from the photosensitive composition. The printed wiring board is produced using the coverlay film and the solder resist.

  本发明的目的是提供一种环氧改性聚酰亚胺，它是一种能在低加工温度下处理的树脂，具有优异的耐热性；感光组合物；覆盖膜，它具有优异的电绝缘性能、焊接耐热性、成膜性、柔韧性和耐化学性；阻焊剂；以及印刷线路板。环氧改性聚酰亚胺是通过合成具有羟基或羧基的聚酰亚胺，然后使聚酰亚胺与环氧化合物反应而得到的。光敏组合物是通过向环氧改性聚酰亚胺中添加光反应引发剂或类似物而获得的。覆盖膜和阻焊可以由光敏组合物形成。使用覆盖膜和阻焊层生产出印刷线路板。