3,11-dihydroxy-tetradecanoic acid methyl ester | 132336-24-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3,11-dihydroxy-tetradecanoic acid methyl ester
• 英文别名: 3,11-Dihydroxy-tetradecansaeure-methylester；opt.-inakt. Ipurolsaeure-methylester；Ipurolsaeuremethylester；Methyl 3,11-dihydroxytetradecanoate
• CAS: 132336-24-4
• 化学式: C₁₅H₃₀O₄
• 分子量: 274.401
• InChiKey: XVHIDNDUMNPTQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3,11-dihydroxy-tetradecanoic acid methyl ester 在 chromium(VI) oxide 作用下， 以 溶剂黄146 为溶剂， 生成 methyl 3,11-dioxotetradecanoate
  参考文献：
  名称：

  Die bestandteile des Giftigen glykosidharzes aus Ipomoea fistulosa mart。等等。

  摘要：

  摘要 从 Ipomoea fistulosa (Convolvulaceae) 的叶子中分离出一种树脂状的高分子量酯糖苷，类似于在其他旋花科地下器官中发现的树脂。它由 7-羟基癸酸、11-羟基十四烷酸、11-羟基十六烷酸和 3,11-二羟基十四烷酸与 d-葡萄糖、d-岩藻糖、d-奎诺糖和 l-的几个残基糖苷结合组成鼠李糖形成糖苷酸，当量重量为 800 至 1300。一部分 7-羟基癸酸被分离为 β-d-喹诺酮苷。糖苷酸相互酯化，形成平均分子量约为 25,000 的密切相关聚酯的混合物，在超速离心机中显示出宽分布曲线。

  DOI：

  10.1016/s0031-9422(00)86143-9
• 作为产物：
  描述：

  甲醇 、 3,11-二羟基-十四烷酸 在 盐酸 作用下， 生成 3,11-dihydroxy-tetradecanoic acid methyl ester
  参考文献：
  名称：

  Power; Rogerson, Chemisches Zentralblatt, 1908, vol. 79, # II, p. 887

  摘要：

  DOI：

文献信息

• Okabe,H. et al., Chemical and pharmaceutical bulletin, 1971, vol. 19, p. 2394 - 2403
  作者：Okabe,H. et al.

  DOI：——

  日期：——
• Kawasaki,T. et al., Chemical and pharmaceutical bulletin, 1971, vol. 19, p. 1144 - 1149
  作者：Kawasaki,T. et al.

  DOI：——

  日期：——
• MULTIFUNCTIONAL FATTY ACID DERIVATIVES AND BIOSYNTHESIS THEREOF
  申请人：Genomatica, Inc.

  公开号：EP3810778A1

  公开（公告）日：2021-04-28
• Multifunctional Fatty Acid Derivatives And Biosynthesis Thereof
  申请人：Genomatica, Inc.

  公开号：US20210189439A1

  公开（公告）日：2021-06-24

  The disclosure relates to the field of specialty chemicals and methods for their synthesis. In embodiments, the disclosure provides novel multifunctional fatty acid derivative molecules such as e.g., fatty triols, fatty tetrols, dihydroxy fatty acids, etc. The disclosure further provides derivatives of the disclosed multifunctional molecules which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc. The disclosure further provides biochemical pathways, recombinant microorganisms and methods for the biological production of various multifunctional fatty acid derivatives.
• [EN] MULTIFUNCTIONAL FATTY ACID DERIVATIVES AND BIOSYNTHESIS THEREOF<br/>[FR] DÉRIVÉS MULTIFONCTIONNELS D'ACIDE GRAS ET BIOSYNTHÈSE CORRESPONDANTE
  申请人：REG LIFE SCIENCES LLC

  公开号：WO2019217226A1

  公开（公告）日：2019-11-14

  The disclosure relates to the field of specialty chemicals and methods for their synthesis. In embodiments, the disclosure provides novel multifunctional fatty acid derivative molecules such as e.g., fatty triols, fatty tetrols, dihydroxy fatty acids, etc. The disclosure further provides derivatives of the disclosed multifunctional molecules which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc. The disclosure further provides biochemical pathways, recombinant microorganisms and methods for the biological production of various multifunctional fatty acid derivatives.