(+/-)-trans-cyclohexene-(3)-dicarboxylic acid-(1.2) | 25079-83-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (+/-)-trans-cyclohexene-(3)-dicarboxylic acid-(1.2)
• 英文别名: (+/-)-trans-Cyclohexen-(3)-dicarbonsaeure-(1.2)；(1S,2S)-cyclohex-3-ene-1,2-dicarboxylic acid
• CAS: 25079-83-8；38765-76-3；38765-77-4
• 化学式: C₈H₁₀O₄
• 分子量: 170.165
• InChiKey: IFDVQVHZEKPUSC-WDSKDSINSA-N

物化性质

• 熔点：
  180 °C
• 沸点：
  390.6±42.0 °C(Predicted)
• 密度：
  1.369±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (+/-)-trans-cyclohexene-(3)-dicarboxylic acid-(1.2) 在 溶剂黄146 、 铂 作用下， 生成 (1S,2S)-1,2-环己烷二甲酸
  参考文献：
  名称：

  Hepatic transplant complicated by hepatic artery thrombosis and bile duct necrosis: case report and potential application of contrast-enhanced MR cholangiography following intravenous mangafodipir trisodium in the emergency room setting

  摘要：

  Biliary tract strictures and leaks are the second most common complications following orthotopic liver transplantation. Nonanastomotic bile duct complications are most often caused by hepatic artery thrombosis and can result in fulminant hepatic necrosis, bile duct strictures, and bile duct leaks that increase the risk of cholangitis, sepsis, and abscess. The emergency physician and radiologist should strongly suspect biliary disease in a post-transplant patient presenting with elevated liver function tests, jaundice, fever, and/or abdominal pain in order to achieve diagnosis and treatment rapidly. We present the case of a liver transplant patient who developed bile duct necrosis and hepatic infarction secondary to hepatic artery thrombosis 5 months after surgery. In addition, we discuss a new contrast-enhanced MR cholangiographic technique that has the potential to be performed in the emergency setting as the only diagnostic test prior to appropriate therapy.

  DOI：

  10.1007/s10140-002-0202-2
• 作为产物：
  描述：

  对硝基甲苯 、 cyclohex-3-ene-1,2-dicarboxylic acid 生成 (+/-)-trans-cyclohexene-(3)-dicarboxylic acid-(1.2)
  参考文献：
  名称：

  Hepatic transplant complicated by hepatic artery thrombosis and bile duct necrosis: case report and potential application of contrast-enhanced MR cholangiography following intravenous mangafodipir trisodium in the emergency room setting

  摘要：

  Biliary tract strictures and leaks are the second most common complications following orthotopic liver transplantation. Nonanastomotic bile duct complications are most often caused by hepatic artery thrombosis and can result in fulminant hepatic necrosis, bile duct strictures, and bile duct leaks that increase the risk of cholangitis, sepsis, and abscess. The emergency physician and radiologist should strongly suspect biliary disease in a post-transplant patient presenting with elevated liver function tests, jaundice, fever, and/or abdominal pain in order to achieve diagnosis and treatment rapidly. We present the case of a liver transplant patient who developed bile duct necrosis and hepatic infarction secondary to hepatic artery thrombosis 5 months after surgery. In addition, we discuss a new contrast-enhanced MR cholangiographic technique that has the potential to be performed in the emergency setting as the only diagnostic test prior to appropriate therapy.

  DOI：

  10.1007/s10140-002-0202-2

文献信息

• Synthesis of heterocyclic derivatives of 3,6-di-tert-butyl-o-benzoquinone by catalytic dehydrocondensation with ethylene glycol, glycerol, and diethanolamine
  作者：T. I. Prokof'eva、V. B. Vol'eva、A. I. Prokof'ev、S. Belostotskaya、N. L. Komissarov、V. V. Ershov

  DOI：10.1007/bf02256976

  日期：2000.8
• BELLUCCI, G.;BERTI, G.;FERRETTI, M.;MASTRORILLI, E.;SILVESTRI, L., J. ORG. CHEM., 1985, 50, N 9, 1471-1474
  作者：BELLUCCI, G.、BERTI, G.、FERRETTI, M.、MASTRORILLI, E.、SILVESTRI, L.

  DOI：——

  日期：——
• Hepatic transplant complicated by hepatic artery thrombosis and bile duct necrosis: case report and potential application of contrast-enhanced MR cholangiography following intravenous mangafodipir trisodium in the emergency room setting
  作者：Kenneth M. Vitellas、Sangeeta Guttikonda

  DOI：10.1007/s10140-002-0202-2

  日期：2002.7

  Biliary tract strictures and leaks are the second most common complications following orthotopic liver transplantation. Nonanastomotic bile duct complications are most often caused by hepatic artery thrombosis and can result in fulminant hepatic necrosis, bile duct strictures, and bile duct leaks that increase the risk of cholangitis, sepsis, and abscess. The emergency physician and radiologist should strongly suspect biliary disease in a post-transplant patient presenting with elevated liver function tests, jaundice, fever, and/or abdominal pain in order to achieve diagnosis and treatment rapidly. We present the case of a liver transplant patient who developed bile duct necrosis and hepatic infarction secondary to hepatic artery thrombosis 5 months after surgery. In addition, we discuss a new contrast-enhanced MR cholangiographic technique that has the potential to be performed in the emergency setting as the only diagnostic test prior to appropriate therapy.