(3aS,4S,5aR,9aR,9bS)-2,2,8,8-tetramethyl-4-(2-((2-((((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methoxy)methyl)allyl)oxy)ethoxy)hexahydro-[1,3]dioxolo[4',5':4,5]pyrano[3,2-d][1,3]dioxine | 950755-66-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧吡喃
• 英文名称: (3aS,4S,5aR,9aR,9bS)-2,2,8,8-tetramethyl-4-(2-((2-((((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methoxy)methyl)allyl)oxy)ethoxy)hexahydro-[1,3]dioxolo[4',5':4,5]pyrano[3,2-d][1,3]dioxine
• CAS: 950755-66-5
• 化学式: C₃₀H₄₈O₁₃
• 分子量: 616.703
• InChiKey: SJDGZXPIQJYUEM-XWMLNZKZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.39
• 重原子数：
  43.0
• 可旋转键数：
  10.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  119.99
• 氢给体数：
  0.0
• 氢受体数：
  13.0

反应信息

• 作为反应物：
  描述：

  (3aS,4S,5aR,9aR,9bS)-2,2,8,8-tetramethyl-4-(2-((2-((((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methoxy)methyl)allyl)oxy)ethoxy)hexahydro-[1,3]dioxolo[4',5':4,5]pyrano[3,2-d][1,3]dioxine 在 氧气 、 臭氧 、 sodium tetrahydroborate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 16.0h， 以85%的产率得到
  参考文献：
  名称：

  Synthesis of new polyether glycodendrons as oligosaccharide mimetics

  摘要：

  Divalent and tetravalent glycomimetics based on polyether glycodendrons have been prepared. The branched scaffolds were decorated with galactose moieties on one hand and were elaborated into new glycodendrons of a 'mixed' type on the other, carrying both galactose and mannose moieties as biologically important sugar epitopes. All synthesized glycodendrons possess a focal point that can be employed for further derivatization and functionalization. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2007.05.005
• 作为产物：
  描述：

  (1R,2S,6S,7S,9R)-7-[2-[2-(chloromethyl)prop-2-enoxy]ethoxy]-4,4,12,12-tetramethyl-3,5,8,11,13-pentaoxatricyclo[7.4.0.02,6]tridecane 、 双丙酮半乳糖 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以63%的产率得到(3aS,4S,5aR,9aR,9bS)-2,2,8,8-tetramethyl-4-(2-((2-((((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methoxy)methyl)allyl)oxy)ethoxy)hexahydro-[1,3]dioxolo[4',5':4,5]pyrano[3,2-d][1,3]dioxine
  参考文献：
  名称：

  Synthesis of new polyether glycodendrons as oligosaccharide mimetics

  摘要：

  Divalent and tetravalent glycomimetics based on polyether glycodendrons have been prepared. The branched scaffolds were decorated with galactose moieties on one hand and were elaborated into new glycodendrons of a 'mixed' type on the other, carrying both galactose and mannose moieties as biologically important sugar epitopes. All synthesized glycodendrons possess a focal point that can be employed for further derivatization and functionalization. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2007.05.005