庚二酸二乙烯基酯 | 10355-48-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 庚二酸二乙烯基酯
• 英文名称: heptanedioic acid divinyl ester
• 英文别名: Heptandisaeure-divinylester；Heptan-1,7-disaeuredivinylester；Pimelinsaeure-divinylester；Bis(ethenyl) heptanedioate
• CAS: 10355-48-3
• 化学式: C₁₁H₁₆O₄
• 分子量: 212.246
• InChiKey: BTZZNDXVEDBCQC-UHFFFAOYSA-N

物化性质

• 沸点：
  132-135 °C(Press: 3 Torr)
• 密度：
  1.024±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  庚二酸二乙烯基酯 、 tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate 在 Novozyme 435 lipase 作用下， 以 甲基叔丁基醚 为溶剂， 反应 8.0h， 生成 (S)-tert-butyl 4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate 、 (R)-tert-butyl 4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate 、
  参考文献：
  名称：

  Novozyme 435 lipase mediated enantioselective kinetic resolution: a facile method for the synthesis of chiral tetrahydroquinolin-4-ol and tetrahydro-1H-benzo[b]azepin-5-ol derivatives

  摘要：

  Vinyl 2-chloroacetate was used as an efficient acyl donor for enantioselective acylation of racemic 1,2,3,4-tetrahydroquinolin-4-ols and 2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ols with Novozyme 435 lipase. Two enantiocomplimentary tetrahydroquinolin-4-ol or tetrahydro-1H-benzo[b]azepin-5-ol derivatives could be smoothly obtained in good to excellent yields and ee values at the same time. Noteworthily, large scale preparation experiment was also demonstrated when amplified the reaction system to 10 g scale experiment, and products were obtained with high yields and ee values. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.05.066
• 作为产物：
  描述：

  乙酸乙烯酯 、 庚二酸 在 硫酸 、 mercury(II) diacetate 作用下， 生成 庚二酸二乙烯基酯
  参考文献：
  名称：

  Schostakowskii et al., Zhurnal Prikladnoi Khimii, 1957, vol. 30, p. 816; engl.Ausg.S.865

  摘要：

  DOI：

文献信息

• POLYESTER COPOLYMER
  申请人：Avantium Knowledge Centre B.V.

  公开号：EP3625283A1

  公开（公告）日：2020-03-25
• Polyester Copolymer
  申请人：Avantium Knowledge Centre B.V.

  公开号：US20210139645A1

  公开（公告）日：2021-05-13

  A polyester copolymer, having a number average molecular weight of equal to or more than 4000 grams/mole and having a glass transition temperature of less than 160° C., containing: (a) in the range from equal to or more than 45 mole % to equal to or less than 50 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more bicyclic diol monomer units, wherein such one or more bicyclic diol monomer units is/are derived from one or more bicyclic diols chosen from the group consisting of isosorbide, isoidide, isomannide, 2,3:4,5-di-O-methylene-galactitol and 2,4:3,5-di-O-methylene-D-mannitol; (b) in the range from equal to or more than 25 mole % to equal to or less than 49.9 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of an oxalate monomer unit; (c) in the range from equal to or more than 0.1 mole % to equal to or less than 25 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more linear C3-C12 dicarboxylate monomer units; and (d) optionally equal to or more than 0 mole % to equal to or less than 5 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more additional monomer units. A process for producing such a polyester copolymer, a composition containing such polyester copolymer, a method for manufacturing an article comprising the use of one or more of such polyester copolymers and an article obtained or obtainable by such a method.
• [EN] POLYESTER COPOLYMER<br/>[FR] COPOLYMÈRE DE POLYESTER
  申请人：AVANTIUM KNOWLEDGE CENTRE BV

  公开号：WO2018211132A1

  公开（公告）日：2018-11-22

  A polyester copolymer, having a number average molecular weight of equal to or more than 4000 grams/mole and having a glass transition temperature of less than 160°C, containing: (a) in the range from equal to or more than 45 mole % to equal to or less than 50 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more bicyclic diol monomer units, wherein such one or more bicyclic diol monomer units is/are derived from one or more bicyclic diols chosen from the group consisting of isosorbide, isoidide, isomannide, 2,3:4,5-di-O-methylene-galactitol and 2,4:3,5-di-O-methylene-D- mannitol; (b) in the range from equal to or more than 25 mole % to equal to or less than 49.9 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of an oxalate monomer unit; (c) in the range from equal to or more than 0.1 mole % to equal to or less than 25 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more linear C3-C12 dicarboxylate monomer units; and (d) optionally equal to or more than 0 mole % to equal to or less than 5 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more additional monomer units. A process for producing such a polyester copolymer, a composition containing such polyester copolymer, a method for manufacturing an article comprising the use of one or more of such polyester copolymers and an article obtained or obtainable by such a method.
• Novozyme 435 lipase mediated enantioselective kinetic resolution: a facile method for the synthesis of chiral tetrahydroquinolin-4-ol and tetrahydro-1H-benzo[b]azepin-5-ol derivatives
  作者：Xiaojian Zhou、Daijun Zheng、Baodong Cui、Wenyong Han、Yongzheng Chen

  DOI：10.1016/j.tet.2015.05.066

  日期：2015.7

  Vinyl 2-chloroacetate was used as an efficient acyl donor for enantioselective acylation of racemic 1,2,3,4-tetrahydroquinolin-4-ols and 2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ols with Novozyme 435 lipase. Two enantiocomplimentary tetrahydroquinolin-4-ol or tetrahydro-1H-benzo[b]azepin-5-ol derivatives could be smoothly obtained in good to excellent yields and ee values at the same time. Noteworthily, large scale preparation experiment was also demonstrated when amplified the reaction system to 10 g scale experiment, and products were obtained with high yields and ee values. (C) 2015 Elsevier Ltd. All rights reserved.
• Schostakowskii et al., Zhurnal Prikladnoi Khimii, 1957, vol. 30, p. 816; engl.Ausg.S.865
  作者：Schostakowskii et al.

  DOI：——

  日期：——