2-氧代十一烷酸 | 34634-92-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 中文名称: 2-氧代十一烷酸
• 英文名称: α-oxoundecanoic acid
• 英文别名: 2-oxoundecanoic acid；2-oxo-undecanoic acid；2-Oxo-undecansaeure；α-Oxo-n-undecansaeure；α-Keto-undecansaeure；2-Oxo-undecancarbonsaeure
• CAS: 34634-92-9
• 化学式: C₁₁H₂₀O₃
• 分子量: 200.278
• InChiKey: GIBJGNIQPMQQIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-氧代十一烷酸 在 钯 、 丁酮 作用下， 生成 2-羟基十一烷酸
  参考文献：
  名称：

  758.羰基化合物合成的实验。第六部分 酮和β-酮​​酯的新合成

  摘要：

  DOI：

  10.1039/jr9520003945
• 作为产物：
  描述：

  N-(ethoxycarbonyl)-2-(ethoxycarbonyloxy)-2-undecenamide 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 5.0h， 生成 2-氧代十一烷酸
  参考文献：
  名称：

  Zul'karnaev, R. I.; Fedotov, A. S.; Lapkin, I. I., Journal of general chemistry of the USSR, 1992, vol. 62, # 2.2, p. 316 - 321

  摘要：

  DOI：

文献信息

• [EN] HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM<br/>[FR] HALOALCENES, PROCEDE DE PRODUCTION D'HALOALCENES ET PESTICIDES CONTENANT CES HALOALCENES
  申请人：ISHIHARA SANGYO KAISHA

  公开号：WO2004052872A1

  公开（公告）日：2004-06-24

  ABSTRACT A novel haloalkene compound represented by the formula (I), useful as an active ingredient of a pesticide, is presented: wherein each of X1 and X2 is halogen, Y is a hydrogen atom, halogen, alkyl or the like, n is from 0 to 5, A is an oxygen atom or a sulfur atom, G is a hydrogen atom, alkyl, acyl or the like, and Q is a 5- to 12-membered heterocyclic group (the heterocyclic group may be substituted) containing an optional hetero atom selected from an oxygen atom, a sulfur atom and a nitrogen atom, alkyl which may be substituted by W, alkenyl which may be substituted by W, alkynyl which may be substituted by W, or cycloalkyl which may be substituted by W, wherein W is halogen, alkoxy, alkylthio, hydroxyl, cyano, nitro or phenyl which may be substituted.

  摘要：提供了一种新型卤烯化合物，其化学式表示为（I），可作为杀虫剂的活性成分：其中X1和X2中的每一个是卤素，Y是氢原子，卤素，烷基或类似物，n为0至5，A是氧原子或硫原子，G是氢原子，烷基，酰基或类似物，Q是一个含有5至12个成员的杂环基团（杂环基团可能被取代），其中可选地包含从氧原子、硫原子和氮原子中选择的一个杂原子，烷基可被W取代，烯基可被W取代，炔基可被W取代，或环烷基可被W取代，其中W是卤素，烷氧基，烷基硫基，羟基，氰基，硝基或可能被取代的苯基。
• Method and agents for measuring protein aging
  申请人：THE ROCKEFELLER UNIVERSITY

  公开号：EP0322402A2

  公开（公告）日：1989-06-28

  A test kit is provided for the detection and/or determination of one of the components selected from the group consisting of advanced glycosylation end products of polypeptides, and the specific binding partners thereto, according to a predetermined protocol, comprising a labelled component which has been obtained by coupling a component of one of said advanced glycosylation end products to a detectable label, and one or more additional immunochemical reagents.

  本发明提供了一种检测试剂盒，用于按照预定方案检测和/或确定选自多肽晚期糖基化终产物及其特异性结合伙伴组的成分之一，该试剂盒包括通过将所述晚期糖基化终产物之一的成分与可检测的标签偶联而获得的标记成分，以及一种或多种附加免疫化学试剂。
• Genetically modified phenylpyruvate decarboxylase, processes to prepare, and uses thereof
  申请人：Dow Global Technologies LLC

  公开号：US10260060B2

  公开（公告）日：2019-04-16

  Modification of the amino acid sequence of a phenylpyruvate decarboxylase from Azospirillum brasilense produces a novel group of phenylpyruvate decarboxylases with improved specificity to certain substrates, including in particular C7-C11 2-ketoacids such as, for example, 2-ketononanoate and 2-keto-octanoate. This specificity enables effective use of the phenylpyruvate decarboxylase in, for example, an in vivo process wherein 2-ketobutyrate or 2-ketoisovalerate are converted to C7-C11 2-ketoacids, and the novel phenylpyruvate decarboxylase converts the C7-C11 2-ketoacid to a C6-C10 aldehyde having one less carbon than the 2-ketoacid. Ultimately, through contact with additional enzymes, such C6-C10 aldehydes may be converted to, for example, C6-C10 alcohols, C6-C10 carboxylic acids, C6-C10 alkanes, and other derivatives. Use of the novel genetically modified phenylpyruvate decarboxylases may represent a lower cost alternative to non-biobased approaches.

  对来自巴西氮孢霉菌（Azospirillum brasilense）的苯丙酮酸脱羧酶的氨基酸序列进行修改，产生了一组新型的苯丙酮酸脱羧酶，该酶对某些底物具有更好的特异性，其中特别包括 C7-C11 2-酮酸，例如 2-酮酸和 2-酮辛酸。这种特异性使苯基丙酮酸脱羧酶能够有效地用于体内工艺，例如，2-酮丁酸或2-酮异戊酸转化为C7-C11 2-酮酸，新型苯基丙酮酸脱羧酶将C7-C11 2-酮酸转化为比2-酮酸少一个碳的C6-C10醛。最终，通过与其他酶接触，这种 C6-C10 醛可转化为 C6-C10 醇、C6-C10 羧酸、C6-C10 烷烃和其他衍生物。使用新型转基因苯丙酮酸脱羧酶可能是一种成本较低的替代方法。
• Processes to prepare elongated 2-ketoacids and C5-C10 compounds therefrom via genetic modifications to microbial metabolic pathways
  申请人：Dow Global Technologies LLC

  公开号：US10995322B2

  公开（公告）日：2021-05-04

  Genetically modified isopropylmalate synthases, processes for preparing a C7-C11 2-ketoacids utilizing genetically modified isopropylmalate synthases, and microbial organisms including genetically modified isopropylmalate synthases are described. The genetically modified isopropylmalate synthases, processes for preparing a C7-C11 2-ketoacids, and microbial organisms including genetically modified isopropylmalate synthases can be particularly useful for producing corresponding Cn_1 aldehydes, alcohols, carboxylic acids, and Cn_2 alkanes both in vivo and in vitro.

  本文描述了转基因异丙基丙二酸合酶、利用转基因异丙基丙二酸合酶制备 C7-C11 2-酮酸的工艺以及包括转基因异丙基丙二酸合酶的微生物。转基因异丙基丙二酸合酶、制备 C7-C11 2-酮酸的工艺和包括转基因异丙基丙二酸合酶的微生物在体内和体外生产相应的 Cn_1 醛、醇、羧酸和 Cn_2 烷烃时特别有用。
• Genetically modified isopropylmalate isomerase enzyme complexes and processes to prepare elongated 2-ketoacids and C5-C10 compounds therewith
  申请人：Dow Global Technologies LLC

  公开号：US11230705B2

  公开（公告）日：2022-01-25

  Genetically modified isopropylmalate isomerase enzyme complexes (e.g., LeuCD′ enzyme complexes), microbial organisms including genetically modified isopropylmalate isomerase enzyme complexes (e.g., LeuCD′), and processes for preparing C7-C11 2-ketoacids with genetically modified isopropylmalate isomerase enzyme complexes (e.g., LeuCD′). The genetically modified isopropylmalate isomerase enzyme complexes (e.g., LeuCD′ enzyme complexes), microbial organisms, and processes for preparing C7-C11 2-ketoacids can be used to produce C6-C10 aldehydes, alkanes, alcohols, and carboxylic acids, both in vivo and in vitro.

  转基因异丙基丙二酸异构酶酶复合物(如LeuCD′酶复合物)、包括转基因异丙基丙二酸异构酶酶复合物(如LeuCD′)在内的微生物、以及用转基因异丙基丙二酸异构酶酶复合物(如LeuCD′)制备C7-C11 2-酮酸的工艺。转基因异丙基丙二酸异构酶复合物（如LeuCD′酶复合物）、微生物和制备C7-C11 2-酮酸的工艺可用于在体内和体外生产C6-C10醛、烷、醇和羧酸。