2,5-bis(4-methoxyphenylhydroxymethyl)tellurophene | 1237798-17-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,5-bis(4-methoxyphenylhydroxymethyl)tellurophene
• 英文别名: [5-[Hydroxy-(4-methoxyphenyl)methyl]tellurophen-2-yl]-(4-methoxyphenyl)methanol
• CAS: 1237798-17-2
• 化学式: C₂₀H₂₀O₄Te
• 分子量: 451.976
• InChiKey: TZLYHOAFDVIBPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.92
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,5-bis(4-methoxyphenylhydroxymethyl)tellurophene 、 2,5-di[2-pyrrolo(4-methoxyphenyl)methyl]tellurophene 在 三氟化硼乙醚 、 四氯苯醌 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以0.5 g的产率得到5,10,15,20-tetra(4-methoxyphenyl)-21,23-ditelluraporphyrin
  参考文献：
  名称：

  Novel 21,23-Ditelluraporphyrins and the First 26,28-Ditellurasapphyrin and 30,33-Ditellurarubyrin

  摘要：

  21,23-Ditelluraporphyrins 3, 9, and 16-18 bearing phenyl, 4-methoxyphenyl, and/or 3,4, 5-trimethoxyphenyl meso substituents were prepared by the condensation of 2,5-di[hydroxy-(aryl)methyl]tellurophenes 12 with 2,5-di[2-pyrrolo(aryl)methyl]tellurophenes 15 in the presence of BF3 etherate followed by oxidation with p-chloranil. Compounds 15 were prepared from tellurophenes 12 with pyrrole and BF(3)-etherate Tellurophenes 12 were prepared in 44-72% isolated yield by the addition of 1,6-diarylhexa-2,4-diyn-1,6-diols 13 to the reduction product of Tc powder and LiBHEt(3). No additional Lewis acid was necessary in these reactions Coupling of 1-aryl-2-propyn-1-ols(14) with CuCl, pyridine, and air in MeOH gave diyndiols 13 26,28-Ditellurasapphyrin 10 was isolated in 0 6% yield from the reaction mixture that produced 9 in 12% isolated yield The X-ray structure of 10 showed a nearly planar sapphyrin core with the Te atoms of both tellurophene rings pointing to the center of the core 30,33-Ditellurarubyrin 11 was isolated in 32% yield by the reaction of two equivalents of trifluoroacetic acid with tellurophene dipyrrane 15c (125)Tc NMR spectra were recorded for the compounds of this study

  DOI：

  10.1021/om100570z
• 作为产物：
  描述：

  1'-羟基-2',3'-去氢草蒿脑 在 碲化氢 、 sodium tetrahydroborate 、 copper(l) iodide 、 nickel(II) chloride hexahydrate 、 四甲基乙二胺 、 氧气 、 silver(I) acetate 作用下， 以 四氢呋喃 、 甲醇 、 水 为溶剂， 反应 1.0h， 生成 2,5-bis(4-methoxyphenylhydroxymethyl)tellurophene
  参考文献：
  名称：

  灵活的卟啉-环戊二烯杂化物：中四四芳基双活泼卟啉的非卟啉构象

  摘要：

  通过从5、10、15、20-四芳基-中挤出碲原子合成了环戊二烯-卟啉杂合物，即diaaza缺乏的卟啉5,10,15,20-四芳基-21,23-divacataporphyrin。用HCl处理的21,23-二telluraporphyrin。此外，在同一反应中还形成了单氮杂缺陷型5,10,15,20-四芳基-21-碲-23-vacataporphyrin。vacataporphyrin家族的两个新成员通过X射线晶体学，UV / Vis和NMR光谱进行了表征。这些芳族分子保留了母体四芳基卟啉的基本结构和光谱特征。21,23-二ivacataporphyrin和21-tellura-23-vacataporphyrin的X射线晶体结构显示出典型的卟啉模式。分子不是严格平面的，并且显示出环烯部分的变形。N22⋅⋅⋅N24距离（5.23和5。09Å）比普通卟啉要长得多。对于21,23-二ivacataporphyrin，可变温度1

  DOI：

  10.1002/chem.201002765

文献信息

• A flexible expanded heterocorrole: Tellura[22]porphyrin(6.1.1.0)
  作者：Sandra Hojniak-Thyssen、Michał Szczepaniak、Lechosław Latos-Grażyński、Ewa Pacholska-Dudziak

  DOI：10.1142/s1088424619501621

  日期：2019.12

  from meso-aryl-26,28-ditellurasapphyrin, leading to a structure where one tellurophene ring of the substrate is replaced by a bridging acyclic four-carbon unit. This aromatic porphyrin-annulene hybrid is conformationally flexible in solution, on account of the C4 unit adopting two different configurations: trans–cis–trans or all-trans. Studies of the dynamic behavior of tellura[22]porphyrin(6.1.1.0)

  合成了一种扩展的杂环，内消旋-四芳基-碲[22]卟啉(6.1.1.0)，包含一个联吡咯部分和一个六碳长链。反应路径通过一个受控的酸促进从 meso-aryl-26,28-ditellurasapphyrin 中挤出一个碲原子进行，从而形成一种结构，其中底物的一个碲苯环被桥连无环四碳单元取代。这种芳族卟啉-环烯杂化物在溶液中具有构象柔性4单元采用两种不同的配置：反式-顺式-反式或全反式。碲[22]卟啉(6.1.1.0)在溶液中的动力学行为研究通过以下方法进行1手125核磁共振波谱。还给出了具有梯形大环骨架的全反式的X射线结构。
• Metalation of Tellurophene: Reactivity of 21,23-Ditelluraporphodimethene toward Palladium(II), Platinum(II), and Rhodium(I)
  作者：Grzegorz Vetter、Agata Białońska、Ewa Pacholska-Dudziak

  DOI：10.1021/acs.inorgchem.2c03777

  日期：2023.2.20

  tellurophene rings, reacted with palladium(II), platinum(II), and rhodium(I) following two different paths. Palladium(II) formed bonds to two tellurium donors of the macrocycle, yielding a side-on coordination compound, with a square planar (Te2Cl2) metal ion environment. An alternative reaction path has been observed for ditelluraporphodimethene with platinum(II) or rhodium(I) in high boiling solvents

  Ditelluraporphodimethene 是一种含有两个碲吩环的非芳香族卟啉类化合物，它与钯 (II)、铂 (II) 和铑 (I) 按照两种不同的路径进行反应。钯 (II) 与大环的两个碲供体形成键，产生侧向配位化合物，具有方形平面 (Te 2 Cl 2) 金属离子环境。在高沸点溶剂中，已经观察到二碲卟啉二甲烯与铂 (II) 或铑 (I) 的替代反应路径。这些条件导致了深刻的转变，即一个碲原子与金属原子的交换，导致形成含有金属环戊二烯环的有机金属物种，即 21-platina-23-telluraporphodimethene 和 21-rhoda-23-telluraporphodimethene。取代反应选择性地在分子的共轭部分内的碲吩环上进行，即与两个 sp 2 内消旋碳原子结合的碲吩环。在铂金的情况下，交易所伴随着一个金币-芳基环与形成的铂环戊二烯环融合，铂（II）大环与氯
• Incorporation of the 1,5-Naphthalene Subunit into Heteroporphyrin Structure: Toward Helical Aceneporphyrinoids
  作者：Bartosz Szyszko、Ewa Pacholska-Dudziak、Lechosław Latos-Grażyński

  DOI：10.1021/jo4006624

  日期：2013.5.17

  5,10,15,20-Tetraaryl-22-hetero-1,5-naphthiporphyrins, which contain a 1,5-naphthylene moiety instead of one pyrrole embedded in the macrocyclic framework of heteroporphyrins, were obtained by the [3 + 1] approach using the 1,5-naphthylene analogue of tripyrrane (1,5-bis(phenyl(2-pyrolyl)methyl)naphthalene) and 2,5-bis(arylhydroxymethyl)-heterocyclopentadiene (heterocyclopentadiene: thiophene, selenophene, tellurophene). The steric constraints, imposed by the substitution mode of the 1,5-naphthylene building block, resulted in the specific helical conformation of 22-hetero-1,5-naphthiporphyrins. The spectroscopic and structural properties of these aceneporphyrinoids indicate a lack of macrocycle aromaticity. Their protonation yielded solely dicationic species.