1-(1,2-diphenylpyrazolidin-4-oxy)-3-(carbazol-9-yl)-2-propanol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-(1,2-diphenylpyrazolidin-4-oxy)-3-(carbazol-9-yl)-2-propanol
• 英文别名: 1-carbazol-9-yl-3-(1,2-diphenylpyrazolidin-4-yl)oxypropan-2-ol
• 化学式: C₃₀H₂₉N₃O₂
• 分子量: 463.579
• InChiKey: VOBDVRPBWFJAMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  35
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  40.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,2-二苯肼 在 氢氧化钾 、 溶剂黄146 、 sodium sulfate 作用下， 以 甲醇 为溶剂， 反应 36.0h， 生成 1-(1,2-diphenylpyrazolidin-4-oxy)-3-(carbazol-9-yl)-2-propanol
  参考文献：
  名称：

  Synthesis of 1,2-Diphenylpyrazolidin-4-ol and its Derivatives

  摘要：

  A synthesis of 1,2-diphenylpyrazolidin-4-ol via direct heterocyclization of 1,2-diphenylhydrazine with 1-chloro-2,3-epoxypropane, its O-epoxypropyl-, O-ethyl-, and O-benzylderivatives are described. Novel hydrazone derivatives with pyrazolidine units were also synthesized. The compounds were characterized by spectroscopic methods as well as elemental analyses.

  DOI：

  10.1007/s00706-007-0602-9

文献信息

• Synthesis of 1,2-Diphenylpyrazolidin-4-ol and its Derivatives
  作者：Vytautas Getautis、Giedre Sinkeviciute、Albina Stanisauskaite

  DOI：10.1007/s00706-007-0602-9

  日期：2007.5

  A synthesis of 1,2-diphenylpyrazolidin-4-ol via direct heterocyclization of 1,2-diphenylhydrazine with 1-chloro-2,3-epoxypropane, its O-epoxypropyl-, O-ethyl-, and O-benzylderivatives are described. Novel hydrazone derivatives with pyrazolidine units were also synthesized. The compounds were characterized by spectroscopic methods as well as elemental analyses.