双(5-甲基-2-糠基)二硫化物 | 78818-79-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 中文名称: 双(5-甲基-2-糠基)二硫化物
• 英文名称: bis(5-methyl-2-furfuryl) disulfide
• 英文别名: bis-(5-methyl-furfuryl)-disulfide；Bis-(5-methyl-furfuryl)-disulfid；2-Methyl-5-[(5-methyl-2-furyl)methyldisulfanylmethyl]furan；2-methyl-5-[[(5-methylfuran-2-yl)methyldisulfanyl]methyl]furan
• CAS: 78818-79-8
• 化学式: C₁₂H₁₄O₂S₂
• 分子量: 254.374
• InChiKey: JNKZCMFCCGQXCU-UHFFFAOYSA-N

物化性质

• 沸点：
  344.4±42.0 °C(Predicted)
• 密度：
  1.216±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  76.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  双(5-甲基-2-糠基)二硫化物 在 乙醚 、 氢化铝 作用下， 生成 5-甲基-2-呋喃甲硫醇
  参考文献：
  名称：

  DE485138

  摘要：

  公开号：
• 作为产物：
  描述：

  5-甲基呋喃醛 在 baker's yeast 、 phosphate buffer 作用下， 以 水 为溶剂， 反应 1.0h， 生成 双(5-甲基-2-糠基)二硫化物
  参考文献：
  名称：

  Generation of Thiols by Biotransformation of Cysteine−Aldehyde Conjugates with Baker's Yeast

  摘要：

  Baker's yeast was shown to catalyze the transformation of cysteine-furfural conjugate into 2-furfurylthiol. The biotransformation's yield and kinetics were influenced by the reaction parameters such as pH, incubation mode (aerobic and anaerobic), and substrate concentration. 2-Furfurylthiol wets obtained in an optimal 37% yield when cysteine-furfural conjugate at a 20 mM concentration wets anaerobically incubated with whole cell baker's yeast at pH 8.0 and 30 degreesC. Similarly to 2-furfurylthiol, 5-methyl-2-furfurylthiol (11%), benzylthiol (8%), 2-thiophenemethanethiol (22%), 3-methyl-2-thiophenemethanethiol (3%), and 2-pyrrolemethanethiol (6%) were obtained from the corresponding cysteine-aldehyde conjugates by incubation with baker's yeast. This work indicates the versatile bioconversion capacity of baker's yeast for the generation of thiols from cysteine-alclehyde conjugates. Thanks to its food-grade character, baker's yeast provides a biochemical tool to produce thiols, which can be used as flavorings in foods and beverages.

  DOI：

  10.1021/jf026198j

文献信息

• DE485138
  申请人：——

  公开号：——

  公开（公告）日：——
• Generation of Thiols by Biotransformation of Cysteine−Aldehyde Conjugates with Baker's Yeast
  作者：Tuong Huynh-Ba、Walter Matthey-Doret、Laurent B. Fay、Rachid Bel Rhlid

  DOI：10.1021/jf026198j

  日期：2003.6.1

  Baker's yeast was shown to catalyze the transformation of cysteine-furfural conjugate into 2-furfurylthiol. The biotransformation's yield and kinetics were influenced by the reaction parameters such as pH, incubation mode (aerobic and anaerobic), and substrate concentration. 2-Furfurylthiol wets obtained in an optimal 37% yield when cysteine-furfural conjugate at a 20 mM concentration wets anaerobically incubated with whole cell baker's yeast at pH 8.0 and 30 degreesC. Similarly to 2-furfurylthiol, 5-methyl-2-furfurylthiol (11%), benzylthiol (8%), 2-thiophenemethanethiol (22%), 3-methyl-2-thiophenemethanethiol (3%), and 2-pyrrolemethanethiol (6%) were obtained from the corresponding cysteine-aldehyde conjugates by incubation with baker's yeast. This work indicates the versatile bioconversion capacity of baker's yeast for the generation of thiols from cysteine-alclehyde conjugates. Thanks to its food-grade character, baker's yeast provides a biochemical tool to produce thiols, which can be used as flavorings in foods and beverages.
• Structural effects on intramolecular furan cycloadditions
  作者：Larry L. Klein

  DOI：10.1021/jo00210a046

  日期：1985.5