ethyl 2-(2,3-dihydro-1H-inden-5-yl)-2-oxoacetate | 67900-32-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: ethyl 2-(2,3-dihydro-1H-inden-5-yl)-2-oxoacetate
• 英文别名: ethyl 5-indanylglyoxylate；ethyl indan-5-yl-oxo-acetate；Ethyl indan-5-yloxoacetate
• CAS: 67900-32-7
• 化学式: C₁₃H₁₄O₃
• 分子量: 218.252
• InChiKey: HGCIIKGPFMTDCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ethyl 2-(2,3-dihydro-1H-inden-5-yl)-2-oxoacetate 在 sodium tetrahydroborate 、 水 作用下， 以 乙醇 为溶剂， 反应 3.0h， 生成 indan-1-ylethan-1,2-diol
  参考文献：
  名称：

  Fungicidal Composition

  摘要：

  一种包含以下成分的杀真菌组合物：以式（1）表示的酰胺化合物和二甲基吗啉作为活性成分，以及一种控制植物病害的方法，将以式（1）表示的酰胺化合物和二甲基吗啉的有效量施用于植物或植物生长的土壤。

  公开号：

  EP1609360A1
• 作为产物：
  描述：

  茚满 以74.8%的产率得到ethyl 2-(2,3-dihydro-1H-inden-5-yl)-2-oxoacetate
  参考文献：
  名称：

  Thiazolidine derivatives and production thereof

  摘要：

  一种新的噻唑烷衍生物的化学式如下：##STR1## 其中n代表3到6的整数，其盐具有强烈的醛糖还原酶抑制作用，并可用于哺乳动物的糖尿病性白内障和糖尿病神经病的预防或治疗。

  公开号：

  US04486594A1

文献信息

• Metal-Free Oxidative Esterification of Ketones and Potassium Xanthates: Selective Synthesis of α-Ketoesters and Esters
  作者：Xianglin Luo、Runfa He、Qiang Liu、Yanping Gao、Jingqing Li、Xiuwen Chen、Zhongzhi Zhu、Yubing Huang、Yibiao Li

  DOI：10.1021/acs.joc.9b03272

  日期：2020.4.17

  A novel and efficient oxidative esterification for the selective synthesis of α-ketoesters and esters has been developed under metal-free conditions. In the protocol, various α-ketoesters and esters are available in high yields from commercially available ketones and potassium xanthates. Mechanistic studies have proven that potassium xanthate not only promotes oxidative esterification but also provides

  在无金属条件下，已开发出一种新颖，有效的氧化酯化方法，用于选择性合成α-酮酸酯和酯。在该方案中，可从市售的酮和黄原酸钾以高收率获得各种α-酮酸酯和酯。机理研究证明，黄原酸钾不仅促进了氧化酯化反应，而且为反应提供了烷氧基部分，该反应涉及C-O键的裂解和重构。
• Amide compound and method of controlling plant disease with the same
  申请人：Sakaguchi Hiroshi

  公开号：US20060122065A1

  公开（公告）日：2006-06-08

  A amid compound of the formula (1): wherein, in the formula, R 51 represents a halogen atom, a C1-C6 alkyl group and the like; R 52 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group and the like; R 53 represents a halogen atom and the like; R 56 represents a halogen atom and the like; R 57 represents a hydrogen atom and the like; R 58 and R 59 independently represent a hydrogen atom, a C1-C3 alkyl group and the like; R 60 represents a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C3-C4 alkenyl group, or a C3-C6 alkynyl group; R 61 represents a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C3-C4 alkenyl group or a C3-C6 alkynyl group or a C2-C4 cyanoalkyl group; R 62 , R 63 and R 64 represent a hydrogen atom, a halogen atom and the like; X represents a oxygen atom or a sulfur atom; has an excellent activity against plant diseases.

  一种化合物的公式（1）：其中，在公式中，R51代表卤素原子，C1-C6烷基等；R52代表氢原子，卤素原子，C1-C6烷基等；R53代表卤素原子等；R56代表卤素原子等；R57代表氢原子等；R58和R59分别独立地代表氢原子，C1-C3烷基等；R60代表C1-C4烷基，C1-C4卤代烷基，C3-C4烯基或C3-C6炔基；R61代表C1-C4烷基，C1-C4卤代烷基，C3-C4烯基或C3-C6炔基或C2-C4氰基烷基；R62，R63和R64代表氢原子，卤素原子等；X代表氧原子或硫原子；具有出色的植物病害活性。
• Amides and method for plant diseases control with the same
  申请人：Sakaguchi Hiroshi

  公开号：US20060122064A1

  公开（公告）日：2006-06-08

  N-(α-cyanobenzyl)amide compounds represented by the formula (1): wherein R 1 represents a hydrogen atom; a halogen atom; a C1-C6 alkyl group optionally substituted with a halogen atom or the like; or the like, R 2 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group or the like, R 3 represents a hydrogen atom or the like, R 4 represents a C1-C4 alkyl group, a C3-C4 alkenyl group or the like, R 5 represents a C1-C4 alkyl group, a C3-C4 alkenyl group, or the like, R 6 represents a hydrogen atom or the like, R 7 represents a hydrogen atom or the like, R 8 represents a hydrogen atom or the like, R 9 represents a hydrogen atom or the like, R 10 represents a hydrogen atom or the like, R 11 represents a hydrogen atom or the like, and R 12 represents a hydrogen atom or the like, have excellent control activities against plant diseases.

  化合物N-(α-氰基苯甲基)酰胺，其化学式为(1)，其中R1代表氢原子；卤素原子；C1-C6烷基，可选择性地被卤素原子或类似物取代；或类似物，R2代表氢原子，卤素原子，C1-C6烷基或类似物，R3代表氢原子或类似物，R4代表C1-C4烷基，C3-C4烯基或类似物，R5代表C1-C4烷基，C3-C4烯基或类似物，R6代表氢原子或类似物，R7代表氢原子或类似物，R8代表氢原子或类似物，R9代表氢原子或类似物，R10代表氢原子或类似物，R11代表氢原子或类似物，R12代表氢原子或类似物，具有优异的植物病害控制活性。
• Fungicidal composition
  申请人：Soma Masato

  公开号：US20050282888A1

  公开（公告）日：2005-12-22

  A fungicidal composition comprising: an amide compound represented by formula (1) and dimethomorph as active ingredients, and a method for controlling plant diseases applying effective amount of an amide compound represented by formula (1) and dimethomorph to plant(s) or soil where plant(s) are growing.

  一种杀菌组合物，包括：由式（1）表示的酰胺化合物和二甲菌酯作为活性成分，并且应用由式（1）表示的酰胺化合物和二甲菌酯的有效量控制植物病害的方法，将其施用于植物或植物生长的土壤中。
• AMIDE COMPOUND AND METHOD OF CONTROLLING PLANT DISEASE WITH THE SAME
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1577290A1

  公开（公告）日：2005-09-21

  A amid compound of the formula (1): wherein, in the formula, R51 represents a halogen atom, a C1-C6 alkyl group and the like; R52 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group and the like; R53 represents a halogen atom and the like; R56 represents a halogen atom and the like; R57 represents a hydrogen atom and the like; R58 and R59 independently represent a hydrogen atom, a C1-C3 alkyl group and the like; R60 represents a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C3-C4 alkenyl group, or a C3-C6 alkynyl group; R61 represents a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C3-C4 alkenyl group or a C3-C6 alkynyl group or a C2-C4 cyanoalkyl group; R62, R63 and R64 represent a hydrogen atom, a halogen atom and the like; X represents a oxygen atom or a sulfur atom; has an excellent activity against plant diseases.

  一种式（1）的酰胺化合物： 式中 R51 代表卤素原子、C1-C6 烷基等； R52 代表氢原子、卤素原子、C1-C6 烷基等； R53 代表卤素原子等； R56 代表卤原子等； R57 代表氢原子等； R58 和 R59 独立地代表氢原子、C1-C3 烷基等； R60 代表 C1-C4 烷基、C1-C4 卤代烷基、C3-C4 烯基或 C3-C6 烷炔基；R61代表 C1-C4 烷基、C1-C4 卤代烷基、C3-C4 烯基或 C3-C6 炔基或 C2-C4 氰烷基；R62、R63 和 R64 代表氢原子、卤素原子等；X 代表氧原子或硫原子； 对植物病害具有极佳的活性。