三丁基-(3-乙烯基-2,4-二甲基苯基)锡烷 | 820964-83-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 三丁基-(3-乙烯基-2,4-二甲基苯基)锡烷
• 英文名称: 2,6-dimethyl-3-(tributylstannyl)styrene
• CAS: 820964-83-8
• 化学式: C₂₂H₃₈Sn
• 分子量: 421.254
• InChiKey: ITURLVPBRXFMKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.0
• 重原子数：
  23
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  三丁基-(3-乙烯基-2,4-二甲基苯基)锡烷 在 六甲基磷酰三胺 吡啶 、 lithium hydroxide 、 copper(l) iodide 、 tris(dibenzylideneacetone)dipalladium (0) 、 2,3-二甲基-2-丁基硼烷 、 甲基锂 、 二异丁基氢化铝 、 三苯基膦 作用下， 以 四氢呋喃 、 N-甲基吡咯烷酮 、 甲醇 、 乙醚 、 正己烷 、 二氯甲烷 为溶剂， 反应 56.0h， 生成 3-[3-(2-acetoxyethyl)-2,4-dimethylphenyl]-2,2-dimethylpropanoic acid
  参考文献：
  名称：

  Stannylative Cycloaddition of Enynes Catalyzed by Palladium−Iminophosphine

  摘要：

  Palladium-iminophosphine complex catalyzes stannylative cycloaddition of conjugated enynes using hexabutyldistannoxane as a stannylating agent to afford highly substituted 3-alkenylphenylstannanes regioselectively. Stannylative cross-cycloaddition reactions between different enynes or between enynes and diynes are also achieved. The reaction is successfully applied to a concise synthesis of alcyopterosin N, which has been isolated recently from sub-Antarctic soft coral, Alcyonium paessleri.

  DOI：

  10.1021/ja044429s
• 作为产物：
  描述：

  1-戊烯-3-炔 、 三丁基氧化锡 在 马来酸酐 、 N-[2-(二苯基膦)苯亚甲基]环己胺 作用下， 以 四氢呋喃 为溶剂， 以71%的产率得到三丁基-(3-乙烯基-2,4-二甲基苯基)锡烷
  参考文献：
  名称：

  Stannylative Cycloaddition of Enynes Catalyzed by Palladium−Iminophosphine

  摘要：

  Palladium-iminophosphine complex catalyzes stannylative cycloaddition of conjugated enynes using hexabutyldistannoxane as a stannylating agent to afford highly substituted 3-alkenylphenylstannanes regioselectively. Stannylative cross-cycloaddition reactions between different enynes or between enynes and diynes are also achieved. The reaction is successfully applied to a concise synthesis of alcyopterosin N, which has been isolated recently from sub-Antarctic soft coral, Alcyonium paessleri.

  DOI：

  10.1021/ja044429s

文献信息

• Stannylative Cycloaddition of Enynes Catalyzed by Palladium−Iminophosphine
  作者：Yoshiaki Nakao、Yasuhiro Hirata、Shinjiro Ishihara、Shinichi Oda、Tomoya Yukawa、Eiji Shirakawa、Tamejiro Hiyama

  DOI：10.1021/ja044429s

  日期：2004.12.1

  Palladium-iminophosphine complex catalyzes stannylative cycloaddition of conjugated enynes using hexabutyldistannoxane as a stannylating agent to afford highly substituted 3-alkenylphenylstannanes regioselectively. Stannylative cross-cycloaddition reactions between different enynes or between enynes and diynes are also achieved. The reaction is successfully applied to a concise synthesis of alcyopterosin N, which has been isolated recently from sub-Antarctic soft coral, Alcyonium paessleri.