1-phenoxy-7-nonanol | 126435-91-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-phenoxy-7-nonanol
• 英文别名: 9-Phenoxynonan-3-ol
• CAS: 126435-91-4
• 化学式: C₁₅H₂₄O₂
• 分子量: 236.354
• InChiKey: NVJNELHZWIVJPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,2-环氧丁烷 、 5-苯氧基戊烷基溴 在 lithium,azanidylidenemethylidenecopper,2H-thiophen-2-ide 、 naphthalen-1-yl-lithium 作用下， 生成 1-phenoxy-7-nonanol
  参考文献：
  名称：

  Rieke, Reuben D.; Wu, Tse-Chong; Stinn, Dean E., Synthetic Communications, 1989, vol. 19, # 11-12, p. 1833 - 1840

  摘要：

  DOI：

文献信息

• Rieke, Reuben D.; Wu, Tse-Chong; Stinn, Dean E., Synthetic Communications, 1989, vol. 19, # 11-12, p. 1833 - 1840
  作者：Rieke, Reuben D.、Wu, Tse-Chong、Stinn, Dean E.、Wehmeyer, Richard M.

  DOI：——

  日期：——
• RIEKE, REUBEN D.;WU, TSE-CHONG;STINN, DEAN E.;WEHMEYER, RICHARD M., SYNTH. COMMUN., 19,(1989) N1-12, C. 1833-1840
  作者：RIEKE, REUBEN D.、WU, TSE-CHONG、STINN, DEAN E.、WEHMEYER, RICHARD M.

  DOI：——

  日期：——
• Direct formation and reaction of thienyl-based organocopper reagents
  作者：Reuben D. Rieke、Walter R. Klein、Tse Chong Wu

  DOI：10.1021/jo00061a024

  日期：1993.4

  The preparation of a highly reactive zerovalent copper complex by the direct reduction of lithium (2-thienylcyano)cuprate with preformed lithium naphthalenide is described. This active copper species oxidatively adds to carbon-halogen bonds to form organocopper reagents. The ability to directly form the organocopper reagent from organic halides and active copper allows for the incorporation of a wide variety of functionalities to be present in the organic halides and the organocopper reagents. Significantly, this formulation of active copper was able to oxidatively add to allyl chlorides and acetates at low temperatures to allow the direct formation of allylic organocopper reagents without Wurtz-type homocoupling. These functionalized organocopper compounds are able to undergo a variety of reactions, such as cross-coupling with acid chlorides, 1,4-conjugate addition with alpha,beta-unsaturated carbonyl compounds, and intermolecular and intramolecular epoxide-opening reactions. Subsequently, this copper species avoids the use of phosphine ligands affording the product isolation much more convenient than with phosphine-based organocopper reagents.