4-(tert-butyldimethylsilyloxy)-N-butyl-naphthalimide | 1332455-77-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 4-(tert-butyldimethylsilyloxy)-N-butyl-naphthalimide
• 英文别名: 4-(t-butyldimethylsilyloxy)-N-butyl-naphthalimide；2-butyl-6-[tert-butyl(dimethyl)silyl]oxybenzo[de]isoquinoline-1,3-dione
• CAS: 1332455-77-2
• 化学式: C₂₂H₂₉NO₃Si
• 分子量: 383.563
• InChiKey: NEMHBCYIXFUQMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.62
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(tert-butyldimethylsilyloxy)-N-butyl-naphthalimide 、 四丁基氟化铵 以 乙腈 为溶剂， 生成
  参考文献：
  名称：

  Colorimetric fluoride sensor based on 1,8-naphthalimide derivatives

  摘要：

  A colorimetric chemosensor TBS-NA, 4-(tert-butyldimethylsilyloxy)-N-butyl-naphthalimide was designed and synthesized. Addition of fluoride ion to a CH3CN solution of TBS-NA can result in an obvious color change (from colorless to yellow) and UV-Vis absorption spectral change in a short time. This indicated that TBS-NA had highly selectivity for fluoride detection over other anions, such as Cl-, Br-, I-, HSO4-, ClO4- and AcO- in CH3CN solutions, and the selectively detection was due to the selective cleavage of Si-O bond in TBS-NA by fluoride. The detection limit was calculated to be 0.59 mu M. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2011.04.012
• 作为产物：
  描述：

  4-溴-1,8-萘二甲酸酐 在 咪唑 、 copper(ll) sulfate pentahydrate 、 水 、 氢碘酸 、 溶剂黄146 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 21.0h， 生成 4-(tert-butyldimethylsilyloxy)-N-butyl-naphthalimide
  参考文献：
  名称：

  Colorimetric fluoride sensor based on 1,8-naphthalimide derivatives

  摘要：

  A colorimetric chemosensor TBS-NA, 4-(tert-butyldimethylsilyloxy)-N-butyl-naphthalimide was designed and synthesized. Addition of fluoride ion to a CH3CN solution of TBS-NA can result in an obvious color change (from colorless to yellow) and UV-Vis absorption spectral change in a short time. This indicated that TBS-NA had highly selectivity for fluoride detection over other anions, such as Cl-, Br-, I-, HSO4-, ClO4- and AcO- in CH3CN solutions, and the selectively detection was due to the selective cleavage of Si-O bond in TBS-NA by fluoride. The detection limit was calculated to be 0.59 mu M. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2011.04.012