The present disclosure relates to a separation material comprising a saccharide that is bound via a linker to a matrix for enabling the separation of substances from a liquid that selectively bind to saccharide moieties, to a method for preparing such material, to a method for separating substances from a liquid that selectively bind to saccharides, and to a device comprising a separation material for separating substances from a liquid that selectively bind to saccharides.
The present disclosure relates to a separation material comprising a matrix that is bound to a saccharide, enabling the separation from a liquid of substances that selectively bind the saccharide, to a method for preparing such separation material and a method for separating substances from a liquid that selectively bind a saccharide of the separation material. The present invention further relates to a device comprising a separation material for separating substances from a liquid that selectively bind to the saccharide of the separation material.
The synthesis of a series of 1-phenoxy-3-[[(substituted-amido)alkyl]amino]-2-propanols is described. Many of the compounds are more potent than propanolol as beta blockers, while having cardioselectivity comparable to that of practolol, when given intravenously to anesthetized cats. The structure-activity relationships shown by this series of compounds provide further evidence that the addition of substituents to the alkylamino moeity of a beta blocker can confer cardioselectivity and that amidic substituents are remarkably effective.
LARGE, M. S.;SMITH, L. H., J. MED. CHEM., 1982, 25, N 11, 1286-1292