2,4,6,8-tetramethyl decanoic acid | 2490-33-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,4,6,8-tetramethyl decanoic acid
• 英文别名: 2,4,6,8-Tetramethyldecansaeure；2,4,6,8-Tetramethyl-decansaeure；2,4,6,8-Tetramethyl-decanoic acid；2,4,6,8-tetramethyldecanoic acid
• CAS: 2490-33-7
• 化学式: C₁₄H₂₈O₂
• 分子量: 228.375
• InChiKey: PXMIDIKFWCXFNC-UHFFFAOYSA-N

物化性质

• 沸点：
  330.9±10.0 °C(Predicted)
• 密度：
  0.892±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲基丁醛 在 sodium hydroxide 、 lithium aluminium tetrahydride 、 pyridinium chlorochromate 作用下， 以 1,4-二氧六环 、 乙醚 、 二氯甲烷 、 水 为溶剂， 反应 43.0h， 生成 2,4,6,8-tetramethyl decanoic acid
  参考文献：
  名称：

  Morr, Michael; Wray, Victor; Fortkamp, Jens, Liebigs Annalen der Chemie, 1992, # 5, p. 433 - 440

  摘要：

  DOI：

文献信息

• Branched fatty acid lubricating compositions
  申请人：——

  公开号：US20020120958A1

  公开（公告）日：2002-08-29

  The invention relates to plant cells comprising a recombinant nucleic acid coding for a product which induces or stimulates the synthesis of branched fatty acids in said cells. It also relates to a production process for branched fatty acids using these plant cells or plants containing it.

  本发明涉及含有重组核酸编码产物的植物细胞，该产物可诱导或刺激所述细胞合成支链脂肪酸。本发明还涉及一种利用这些植物细胞或含有它的植物生产支链脂肪酸的工艺。
• Method for producing branched fatty acids using genetically modified plants
  申请人：——

  公开号：US20020120957A1

  公开（公告）日：2002-08-29

  The invention relates to plant cells comprising a recombinant nucleic acid coding for a product which induces or stimulates the synthesis of branched fatty acids in said cells. It also relates to a production process for branched fatty acids using these plant cells or plants containing it.

  本发明涉及含有重组核酸编码产物的植物细胞，该产物可诱导或刺激所述细胞合成支链脂肪酸。本发明还涉及一种利用这些植物细胞或含有它的植物生产支链脂肪酸的工艺。
• Cochleate preparations of fragile nutrients
  申请人：Mannino J. Raphael

  公开号：US20050008686A1

  公开（公告）日：2005-01-13

  The present invention provides novel fragile nutrient cochleates that generally include one or more encochleated fragile nutrients, e.g., beta carotene, and methods for making the same. Also provided are methods for the use and administration of the fragile nutrient cochleates of the invention.

  本发明提供了新型脆性营养素蜗牛胶囊，一般包括一种或多种蜗牛胶囊脆性营养素，如β-胡萝卜素，以及制造这种蜗牛胶囊的方法。本发明还提供了使用和服用本发明脆性营养素耳蜗片的方法。
• Cochleate compositions directed against expression of proteins
  申请人：Gould-Fogerite Susan

  公开号：US20050013855A1

  公开（公告）日：2005-01-20

  Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.

  本文公开了新型 siRNA-蜗牛酸盐和吗啉-蜗牛酸盐组合物。还公开了 siRNA-蜗牛酸盐和吗啉-蜗牛酸盐组合物的制造和使用方法。
• Novel encochleation methods, cochleates and methods of use
  申请人：Mannino J. Raphael

  公开号：US20050013854A1

  公开（公告）日：2005-01-20

  Disclosed are novel methods for making cochleates and cochleate compositions that include introducing a cargo moiety to a liposome in the presence of a solvent. Also disclosed are cochleates and cochleate compositions that include an aggregation inhibitor, and optionally, a cargo moiety. Additionally, anhydrous cochleates that include a protonized cargo moiety, a divalent metal cation and a negatively charge lipid are disclosed. Methods of using the cochleate compositions of the invention, including methods of administration, are also disclosed.

  本发明公开了制造蜗牛酸盐和蜗牛酸盐组合物的新方法，包括在溶剂存在下将货物分子引入脂质体。还公开了蜗牛酸盐和蜗牛酸盐组合物，其中包括一种聚集抑制剂和可选的货物分子。此外，还公开了包括质子化货物分子、二价金属阳离子和负电荷脂质的无水蜗牛酸盐。还公开了使用本发明蜗牛酸盐组合物的方法，包括给药方法。