N-(2-chloroprop-2-enyl)-tert-butylamine | 17026-97-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 英文名称: N-(2-chloroprop-2-enyl)-tert-butylamine
• 英文别名: N-<2-Chlor-allyl>-tert.-butylamin；tert.-Butyl-2-chlor-2-propenylamin；N-(2-Chlor-allyl)-tert.-butylamin；n-Tert-butyl-2-chloroprop-2-en-1-amine；N-(2-chloroprop-2-enyl)-2-methylpropan-2-amine
• CAS: 17026-97-0
• 化学式: C₇H₁₄ClN
• 分子量: 147.648
• InChiKey: FIUOOQWEGAFTEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2,3-二氯丙烯 、 叔丁胺 以 水 为溶剂， 生成 N-(2-chloroprop-2-enyl)-tert-butylamine
  参考文献：
  名称：

  Amines Derived from Dihalopropenes. V.^1a Reaction of 2-Haloallylamines with Various Bases^1b

  摘要：

  DOI：

  10.1021/jo01046a525

文献信息

• Synthesis and reactivity of alkenyl- and alkynyl-substituted β,β-dihalo-and β,β,β-trichloroamines
  作者：Kourosch Abbaspour Tehrani、Sara Stas、Bart Lucas、Norbert De Kimpe

  DOI：10.1016/j.tet.2009.01.034

  日期：2009.3

  beta,beta-Dihalo and beta,beta,beta-trichloroamines, obtained by Lewis acid-promoted Petasis-type reaction of alpha,alpha-dichlorinated and alpha,alpha,alpha-trichlorinated imines or reduction of alpha,alpha-dihaloaldimines, were subjected to a reactivity study and turned out to be remarkably stable compounds. In general, only the bases KO'Bu and NaOMe cause a 1,2-dehydrochlorination with formation of unsaturated alpha-chloroimines Or Unsaturated alpha,alpha-dichloroimines. Hydrolysis of the alpha-chloroimines with aqueous oxalic acid resulted in the formation of the corresponding unsaturated alpha-chloroketones. The reaction of simple beta,beta-dihaloamines with NaOMe and KO'Bu generated 2-haloprop-2-enylmines and 2,2-dimethoxypropylamines. (C) 2009 Elsevier Ltd. All rights reserved.
• Chemistry of nitrogen radicals. VIII. Free-radical addition of monoalkyl-N-chloramines to substituted olefins
  作者：Robert S. Neale、Nancy L. Marcus

  DOI：10.1021/jo01273a021

  日期：1968.9
• Amines Derived from Dihalopropenes. V.^1a Reaction of 2-Haloallylamines with Various Bases^1b
  作者：Albert T. Bottini、Barbara J. King、Robert E. Olsen

  DOI：10.1021/jo01046a525

  日期：1963.11