2,4-dimethyl-pentane-2,4-dithiol | 77618-23-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: 2,4-dimethyl-pentane-2,4-dithiol
• 英文别名: 2,4-Dimethyl-pentan-2,4-dithiol；2,4-dimethyl-2,4-pentanedithiol；2,4-dimethylpentane-2,4-dithiol
• CAS: 77618-23-6
• 化学式: C₇H₁₆S₂
• 分子量: 164.336
• InChiKey: JPFWMGDTDYCPHQ-UHFFFAOYSA-N

物化性质

• 沸点：
  86-87 °C(Press: 2 Torr)
• 密度：
  0.953±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,4-dimethyl-pentane-2,4-dithiol 在 甲醇 、 叔丁基过氧化氢 、 三氯化铁 作用下， 生成 3,3,5,5-Tetramethyl-dithiolan-(1,2)
  参考文献：
  名称：

  Schoeberl; Graefje, Justus Liebigs Annalen der Chemie, 1958, vol. 614, p. 66,79

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4-dibromo-2,4-dimethyl-pentane 、 硫脲 在 甲醇 作用下， 生成 2,4-dimethyl-pentane-2,4-dithiol
  参考文献：
  名称：

  Schoeberl; Graefje, Justus Liebigs Annalen der Chemie, 1958, vol. 614, p. 66,79

  摘要：

  DOI：

文献信息

• Aminosulfonylthiadiazolylureas
  申请人：Velsicol Chemical Corporation

  公开号：US04255182A1

  公开（公告）日：1981-03-10

  Disclosed are compounds of the formula ##STR1## wherein R.sup.1 is alkyl, R.sup.2 is selected from the group consisting of hydrogen and alkyl; or R.sup.1 and R.sup.2 together with the nitrogen atom form a cyclic ring structure having 4 or 5 carbon atoms; m is the integer 0 or 1; when m is 1, R.sup.4 and R.sup.5 are each independently selected from the group consisting of hydrogen and alkyl or up to 3 carbon atoms; when m is 0, R.sup.4 is hydrogen and R.sup.5 is the same as defined above; R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.9 are each independently selected from the group consisting of hydrogen and alkyl; n is an integer from 0 to 2; and Z.sup.1 and Z.sup.2 are each independently selected from the group consisting of oxygen and sulfur. These compounds are useful as herbicides.

  揭示的化合物具有以下结构式##STR1## 其中 R.sup.1 是烷基，R.sup.2 从氢和烷基组成的群体中选择；或者R.sup.1 和R.sup.2 与氮原子一起形成具有4或5个碳原子的环状结构；m 是整数0或1；当 m 为1 时，R.sup.4 和R.sup.5 分别独立地从氢和烷基或最多3个碳原子组成的群体中选择；当 m 为0 时，R.sup.4 是氢，R.sup.5 与上述定义相同；R.sup.3、R.sup.6、R.sup.7、R.sup.8、R.sup.9 分别独立地从氢和烷基组成的群体中选择；n 是0到2之间的整数；Z.sup.1 和Z.sup.2 分别独立地从氧和硫组成的群体中选择。这些化合物可用作除草剂。
• METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF
  申请人：Nakayama Osamu

  公开号：US20110009643A1

  公开（公告）日：2011-01-13

  Provided are 1) a production process for an acrylic ester derivative capable of being a raw material of a polymer for obtaining a photoresist composition capable of forming a photoresist film which is excellent in a reactivity to acid and a heat stability and is less swollen in developing and which has a refractive index of preferably 1.72 or more in 193 nm and can be patterned, 2) an acrylic ester derivative obtained by the above production process and 3) alcohol and ester which are synthetic intermediates for the above acrylic ester derivative.

  提供了以下内容：1）一种丙烯酸酯衍生物的生产工艺，该衍生物可以作为聚合物的原料，用于获得一种光阻组合物，该光阻组合物能形成一种对酸具有良好反应性和热稳定性的光阻膜，并且在显影时膨胀较少，其折射率在193纳米时最好为1.72或更高，并且可以进行图案化；2）通过上述生产工艺获得的丙烯酸酯衍生物；以及3）用于上述丙烯酸酯衍生物的合成中间体醇和酯。
• [EN] METHODS OF PREPARING MACROCYCLIC INDOLES<br/>[FR] PROCÉDÉS DE PRÉPARATION D'INDOLES MACROCYCLIQUES
  申请人：BROAD INST INC

  公开号：WO2020236556A1

  公开（公告）日：2020-11-26

  The present invention relates to methods of preparing substituted indole derivatives of general formula (I) : in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, and intermediate compounds useful for preparing said compounds. These compounds are useful for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

  本发明涉及制备通式（I）的取代吲哚衍生物的方法：其中R1、R2、R3、R4、R5、R6、A和L的定义如本文所述，并且用于制备所述化合物的中间化合物。这些化合物可用于制造用于治疗或预防疾病的药物组合，特别是用作唯一活性成分或与其他活性成分结合使用，尤其是用于治疗过度增殖性疾病。
• Phospholipase inhibitors, including multi-valent phospholipase inhibitors, and use thereof, including as lumen-localized phospholipase inhibitors
  申请人：Chang Han-Ting

  公开号：US20070135383A1

  公开（公告）日：2007-06-14

  The present invention provides methods and compositions for the treatment of phospholipase-related conditions. In particular, the invention provides a method of treating insulin-related, weight-related conditions and/or cholesterol-related conditions in an animal subject. The method generally involves the administration of a non-absorbed and/or effluxed phospholipase A2 inhibitor that is localized in a gastrointestinal lumen.

  本发明提供了治疗磷脂酶相关疾病的方法和组合物。具体地，本发明提供了一种用于治疗动物主体中的胰岛素相关、体重相关和/或胆固醇相关疾病的方法。该方法通常涉及在胃肠道腔中定位的非吸收和/或外流的磷脂酶A2抑制剂的给药。
• Optical material composition and optical material
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US10767015B2

  公开（公告）日：2020-09-08

  The present invention makes it possible to provide an optical material composition containing an episulfide compound (A), a polythiol compound (B), and a photochromic compound (C). The episulfide compound (A) is preferably a compound represented by formula (1), and the polythiol compound (B) is preferably a compound represented by formula (6). (In formula (1), m represents an integer of 0 to 4, and n represents an integer of 0 to 2.) (In formula (6), n represents an integer of 4 to 20, and R1 and R2 may be the same or different and represent H, SH, C1-10 alkyl groups, or C1-10 alkylthiol groups.)

  本发明可提供一种光学材料组合物，其中含有表硫化物化合物（A）、聚硫醇化合物（B）和光致变色化合物（C）。表硫化物化合物（A）最好是由式（1）表示的化合物，而聚硫醇化合物（B）最好是由式（6）表示的化合物。 (在式 (1) 中，m 代表 0 至 4 的整数，n 代表 0 至 2 的整数）。 (在式 (6) 中，n 代表 4 至 20 的整数，R1 和 R2 可以相同或不同，代表 H、SH、C1-10 烷基或 C1-10 烷硫基）。