(1-methylpropoxy)acetic acid | 99116-02-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (1-methylpropoxy)acetic acid
• 英文别名: (1-Methyl-propyloxy)-essigsaeure；sek.-Butyloxy-essigsaeure；2-(Butan-2-yloxy)acetic acid；2-butan-2-yloxyacetic acid
• CAS: 99116-02-6
• 化学式: C₆H₁₂O₃
• mdl: MFCD16153807
• 分子量: 132.159
• InChiKey: IKUWHVIKVZSENZ-UHFFFAOYSA-N

物化性质

• 沸点：
  110-115 °C(Press: 20 Torr)
• 密度：
  1.024±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (1-methylpropoxy)acetic acid 生成 2-sec-butoxyethanoyl chloride
  参考文献：
  名称：

  HAGENAH, JEFFREY A.;OMID, AHMAD

  摘要：

  DOI：
• 作为产物：
  描述：

  sodium monochloroacetic acid 、 仲丁醇 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 生成 (1-methylpropoxy)acetic acid
  参考文献：
  名称：

  SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor

  摘要：

  Extensive SAR has been established in the alkoxy lactone series and this has lead to the discovery of DFP (5,5-dimethyl-3-(2-propoxy)-4-methanesulfonylphenyl)-2-(5H)-furanone), a potent COX-2 inhibitor exhibiting in vivo efficacy in all models studied. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00365-0

文献信息

• 1-carboalkoxyalkyl-3-alkoxy-4-(2'-carboxyphenyl)-azet-2-ones as plant
  申请人：Chevron Research Company

  公开号：US04846873A1

  公开（公告）日：1989-07-11

  Compounds of the formula: ##STR1## wherein R.sup.1 is lower alkyl of 1 to 6 carbon atoms lower alkenyl of 2 to 6 carbon atoms or benzyl; R.sup.2 is lower alkoxy of 1 to 6 carbon atoms, benzyloxy or the group ##STR2## where R.sup.4 is lower alkoxy of 1 to 4 carbon atoms; and R.sup.3 is hydrogen, lower alkyl of 1 to 6 carbon atoms, lower alkyl of 1 to 6 carbon atoms substituted with 1 to 3 trihalomethyl groups, lower haloalkyl of 1 to 6 carbon atoms substituted with 1 to 6 halogen atoms, lower alkenyl of 2 to 6 carbon atoms, arylalkyl of 7 to 12 carbon atoms, lower alkoxyalkyl of 2 to 6 carbon atoms, lower alkylthioalkyl of 2 to 6 carbon atoms, or lower cycloalkyl of 3 to 8 carbon atoms are active as plant growth regulators. Certain of these compounds also show activity as selective herbicides.

  分子式为：##STR1## 其中R.sup.1为1到6个碳原子的低碳基，2到6个碳原子的低烯基或苄基；R.sup.2为1到6个碳原子的低烷氧基，苄氧基或##STR2## 其中R.sup.4为1到4个碳原子的低烷氧基；R.sup.3为氢，1到6个碳原子的低碳基，1到6个碳原子的低碳基，被1到3个三卤甲基基团取代，1到6个碳原子的低卤代烷基，2到6个碳原子的低烯基，7到12个碳原子的芳基烷基，2到6个碳原子的低烷氧基烷基，2到6个碳原子的低烷硫基烷基，或3到8个碳原子的低环烷基的化合物作为植物生长调节剂具有活性。其中某些化合物还表现出选择性除草剂的活性。
• LIQUID COMPOSITION, RECORDING METHOD, AND RECORDED MATTER
  申请人：Gotou Hiroshi

  公开号：US20130101814A1

  公开（公告）日：2013-04-25

  A liquid composition for agglutinating particles having a negative charge which are dispersed in a dispersion liquid, the liquid composition including: an organic acid ammonium salt represented by Formula (1), and water, Formula (1) where R 1 represents a hydroxyl group, a methyl group or a hydrogen atom; and R 2 represents a hydroxyl group or a methyl group.

  一种用于凝聚分散在分散液中的带有负电荷的颗粒的液态组合物，该液态组合物包括：由式（1）表示的有机酸铵盐和水，其中，式（1）中R1表示羟基、甲基或氢原子；R2表示羟基或甲基。
• Dyed photoresist compositions and process
  申请人：ASPECT SYSTEMS CORPORATION

  公开号：EP0345714A2

  公开（公告）日：1989-12-13

  This invention provides improved positive photoresist compositions containing a bis(azophenyl)­resorcinol as a dye.

  本发明提供了含有双（偶氮苯基）间苯二酚作为染料的改进型正性光刻胶组合物。
• Process for preparation of alpha-alkoxy acetic acids and their salts
  申请人：G.D. Searle & Co.

  公开号：EP0434896A1

  公开（公告）日：1991-07-03

  A process for producing an α-alkoxy acetic acids and salts thereof which comprises reacting an alcohol of the formula R-OH wherein R is alkyl, substituted alkyl, or cycloalkyl, or cycloalkyl alkyl with a base in an aprotic organic solvent to give an alkoxide followed by removal of the organic solvent and reaction of the alkoxide with a salt of a monohaloacetic acid in a polar aprotic solvent such as DMSO to give the corresponding alkoxyacetate salt which then may be recovered or may optionally be converted to the corresponding acid by contacting the alkoxy acetate salt with an acid.

  一种生产α-烷氧基乙酸及其盐的工艺，包括使式 R-OH 其中 R 为烷基、取代烷基或环烷基的醇与碱反应，生成烷氧基氧化物，然后除去有机溶剂，使烷氧基氧化物与单卤乙酸的盐在壬烷醇中反应，生成α-烷氧基乙酸及其盐、或环烷基烷基与碱在非烷基有机溶剂中反应生成烷氧基氧化物，然后除去有机溶剂，再将烷氧基氧化物与单卤乙酸盐在极性非烷基溶剂（如二甲基亚砜）中反应生成相应的烷氧基乙酸盐，然后可回收或通过将烷氧基乙酸盐与酸接触转化为相应的酸。
• Polycyanate copolymers prepared from polyfunctional cyanates and fluorinated monocyanates
  申请人：Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.

  公开号：EP1067149A1

  公开（公告）日：2001-01-10

  The present invention is directed to polycyanate copolymers, obtainable by copolymerization of at least one polyfunctional cyanate with at least one monocyanate of the formula N≡C-O-R, wherein R is a straight or branched non-aromatic hydrocarbon radical or a non-aromatic hydrocarbon radical comprising a cyclic structure, the radical having the formula C(R')2-CFR"2 wherein each R' is, independently from the other, hydrogen or fluorine or an optically substituted, preferably fluorinated alkyl or alkenyl group, and each of R" may independently be defined as R' or may have an arylic structure. Preferably, the at least one polyfunctional cyanate is selected from aliphatic or aromatic dicyanates or from oligocyanates comprising a straight chain of 2 to 22 oligomerized monocyanates. The polycyanate copolymer may further comprise an aromatic monocyanate and/or one or more of brominated cyanates. The polycyanate copolymers are advantageously used for the preparation of optical systems, e.g. waveguide structures, because they have low optical losses at 1.3 and 1.55µm.

  本发明涉及聚氰酸酯共聚物，可通过至少一种多官能团氰酸酯与至少一种式 N≡C-O-R 的单氰酸酯共聚而得，其中 R 是直链或支链非芳香烃基或包含环状结构的非芳香烃基、具有式 C(R')2-CFR "2的基团，其中每个 R'独立地为氢或氟或光学取代的、优选氟化的烷基或烯基，每个 R "可独立地定义为 R'或具有丙烯酸结构。优选地，至少一种多官能团氰酸酯选自脂肪族或芳香族二氰酸酯或由 2 至 22 个低聚单氰酸酯直链组成的低聚氰酸酯。聚氰酸酯共聚物可进一步包含芳香族单氰酸酯和/或一种或多种溴化氰酸酯。由于聚氰酸酯共聚物在 1.3 和 1.55µm 波长处的光学损耗较低，因此可用于制备光学系统，如波导结构。