methyl 4-(2-aminoacetamido)butanoate hydrochloride | 208829-63-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 肽模拟物
• 英文名称: methyl 4-(2-aminoacetamido)butanoate hydrochloride
• CAS: 208829-63-4
• 化学式: C₇H₁₄N₂O₃*ClH
• 分子量: 210.661
• InChiKey: WYNCWCDZWMZXEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.56
• 重原子数：
  13.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  81.42
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  sodium tetrachloropalladate(II) 、 methyl 4-(2-aminoacetamido)butanoate hydrochloride 、 双(三苯基正膦基)氯化铵 在 NaOMe 作用下， 以 甲醇 为溶剂， 以48%的产率得到
  参考文献：
  名称：

  Facile Synthesis of Cyclic Tetrapeptides from Nonactivated Peptide Esters on Metal Centers

  摘要：

  The cyclization of dipeptide esters of α-, β-, γ-, and δ-amino acids can be achieved by using NiII , PdII , or CuII templates. The structure of one of the complexes (1) obtained, which was determined by X-ray crystallography, reveals that the anions form layers and are linked to water molecules by hydrogen bonds.

  DOI：

  10.1002/(sici)1521-3773(19980504)37:8<1086::aid-anie1086>3.0.co;2-v

文献信息

• Facile Synthesis of Cyclic Tetrapeptides from Nonactivated Peptide Esters on Metal Centers
  作者：Katharina Haas、Werner Ponikwar、Heinrich Nöth、Wolfgang Beck

  DOI：10.1002/(sici)1521-3773(19980504)37:8<1086::aid-anie1086>3.0.co;2-v

  日期：1998.5.4

  The cyclization of dipeptide esters of α-, β-, γ-, and δ-amino acids can be achieved by using NiII , PdII , or CuII templates. The structure of one of the complexes (1) obtained, which was determined by X-ray crystallography, reveals that the anions form layers and are linked to water molecules by hydrogen bonds.