1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine | 121079-71-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine
• 英文别名: tetrahydro-1,2-pyridazinedicarboxylic acid, diethyl ester；Diethyl 3,4-dihydropyridazine-1,2-dicarboxylate
• CAS: 121079-71-8
• 化学式: C₁₀H₁₆N₂O₄
• 分子量: 228.248
• InChiKey: ZLKCBDXWCZCZDR-UHFFFAOYSA-N

物化性质

• 沸点：
  288.9±33.0 °C(Predicted)
• 密度：
  1.200±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  一氧化碳 、 1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine 在 cis-dichlorobis(triphenylphosphine)platinum(II) 、 氢气 作用下， 以 苯 为溶剂， 反应 45.0h， 生成 1,2-dicarbethoxy-3-formylhexahydropyridazine
  参考文献：
  名称：

  Hydroformylation and hydrocarbethoxylation of 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine and 1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine

  摘要：

  The unsaturated compounds 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine 1 and 1,2-dicarbethoxY-1,2,3,4-tetrahydropyridazine 2 have been hydroformylated and hydrocarbethoxylated in the presence of some well known cobalt, rhodium, palladium and platinum catalysts. The hydroformylation reaction can be tuned by a suitable choice of the catalyst precursor and reaction conditions, thus allowing the synthesis with high selectivity of one of the two possible isomeric aldehydes. The carbonylation reaction is less synthetically useful, since it shows low activity and unsatisfactory chemo- and regio-selectivity. However, the ester 1,2,4-tricarbethoxyhexahydropyridazine 10 can be prepared in good yield from olefin 1 by using the complex [PdCl2(PPh3)2] as the catalyst precursor.

  DOI：

  10.1016/0022-328x(93)80161-4
• 作为产物：
  描述：

  1,2,3,6-四氢吡嗪-1,2-二羧酸二乙酯 在 dichlorotetrakis(triphenylphosphine)ruthenium(II) 作用下， 以 neat (no solvent) 为溶剂， 反应 24.0h， 生成 1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine
  参考文献：
  名称：

  Homogeneous isomerization of 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine by ruthenium complexes

  摘要：

  DOI：

  10.1016/0022-328x(88)87047-5

文献信息

• 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal
  申请人：American Cyanamid Company

  公开号：US05610120A1

  公开（公告）日：1997-03-11

  There is provided a 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.

  提供一种具有结构式I的1-(3-杂环基苯基)-s-三嗪-2,4,6-酮或硫代三嗪化合物。进一步提供了一种包含该化合物的组合物和方法，用于控制不良植物物种。
• 1-(3-heterocyclyphenyl)-S-triazine-2,6,6-oxo or thiotrione herbicidal
  申请人：American Cyanamid Company

  公开号：US05726126A1

  公开（公告）日：1998-03-10

  There is provided a 1-(3-heterocyclylphenyl)-s-triazine-2, 4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.

  提供一种具有结构式I的1-(3-杂环苯基)-s-三嗪-2,4,6-氧或硫代酮化合物。进一步提供了一种包含该化合物的组合物和方法，用于控制不良植物物种。
• Improved metal-ligand complex catalysed processes
  申请人：Union Carbide Chemical & Plastics Technology Corporation

  公开号：EP1764353A1

  公开（公告）日：2007-03-21

  A process for separating one or more cyclic products from a reaction product fluid comprising one or more cyclic reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, a non-polar solvent and said one or more cyclic products, wherein said process comprises: (1) reacting said one or more cyclic reactants in the presence of said metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand and non-polar solvent to form a multiphase reaction product fluid; and (2) separating said multiphase reaction product fluid to obtain a non-polar phase comprising said one or more cyclic reactants, metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand and non-polar solvent and a polar phase comprising said one or more cyclic products.

  一种从包含一种或多种环状反应物、金属有机磷配体络合催化剂、可选游离有机磷配体、非极性溶剂和所述一种或多种环状产物的反应产物流体中分离一种或多种环状产物的工艺，其中所述工艺包括：(1) 在所述金属-有机磷配体络合催化剂、可选游离有机磷配体和非极性溶剂存在下，使所述一种或多种环状反应物发生反应，以形成多相反应产物流体；以及 (2) 分离所述多相反应产物流体，以获得包含所述一种或多种环状反应物、金属-有机磷配体络合催化剂、可选游离有机磷配体和非极性溶剂的非极性相，以及包含所述一种或多种环状产物的极性相。
• Homogeneous isomerization of 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine by ruthenium complexes
  作者：Gloria Menchi、Ugo Matteoli、Alberto Scrivanti、Stefano Paganelli、Carlo Botteghi

  DOI：10.1016/0022-328x(88)87047-5

  日期：1988.10
• Hydroformylation and hydrocarbethoxylation of 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine and 1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine
  作者：G. Menchi、S. Paganelli、U. Matteoli、A. Scrivanti、C. Botteghi

  DOI：10.1016/0022-328x(93)80161-4

  日期：1993.5

  The unsaturated compounds 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine 1 and 1,2-dicarbethoxY-1,2,3,4-tetrahydropyridazine 2 have been hydroformylated and hydrocarbethoxylated in the presence of some well known cobalt, rhodium, palladium and platinum catalysts. The hydroformylation reaction can be tuned by a suitable choice of the catalyst precursor and reaction conditions, thus allowing the synthesis with high selectivity of one of the two possible isomeric aldehydes. The carbonylation reaction is less synthetically useful, since it shows low activity and unsatisfactory chemo- and regio-selectivity. However, the ester 1,2,4-tricarbethoxyhexahydropyridazine 10 can be prepared in good yield from olefin 1 by using the complex [PdCl2(PPh3)2] as the catalyst precursor.