5-methyl-2-(phenyldiazenyl)pyridine | 65295-92-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-methyl-2-(phenyldiazenyl)pyridine
• 英文别名: 5-methyl-2-phenylazo-pyridine；5-Methyl-2-phenylazopyridin；5-Methyl-2-[(E)-phenyldiazenyl]pyridine；(5-methylpyridin-2-yl)-phenyldiazene
• CAS: 65295-92-3
• 化学式: C₁₂H₁₁N₃
• 分子量: 197.239
• InChiKey: ZCYIBFHOBFDPFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  37.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-methyl-2-(phenyldiazenyl)pyridine 在 N-溴代丁二酰亚胺(NBS) 、 过氧化苯甲酰 作用下， 以 四氯化碳 为溶剂， 反应 12.0h， 以73%的产率得到5-bromomethyl-2-(phenyldiazenyl)pyridine
  参考文献：
  名称：

  Azopyridine-imidacloprid derivatives as photoresponsive neonicotinoids

  摘要：

  A series of imidacloprid derivatives containing an azopyridine motif as a photoswitchable functional group were designed and synthesized. The new version of photoresponsive imidacloprid analogues showed improved solubility in comparison with their azobenzene analogues. 1.2 to 2-fold activity difference was observed for these azopyridine-imidacloprids against house fly (Musca domestica) and cowpea aphid (Aphis craccivora) upon irradiation. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cclet.2016.03.033
• 作为产物：
  描述：

  苯胺 在 oxone||potassium monopersulfate triple salt 、 sodium hydroxide 作用下， 以 二氯甲烷 、 水 、 甲苯 为溶剂， 反应 1.0h， 生成 5-methyl-2-(phenyldiazenyl)pyridine
  参考文献：
  名称：

  Azopyridine-imidacloprid derivatives as photoresponsive neonicotinoids

  摘要：

  A series of imidacloprid derivatives containing an azopyridine motif as a photoswitchable functional group were designed and synthesized. The new version of photoresponsive imidacloprid analogues showed improved solubility in comparison with their azobenzene analogues. 1.2 to 2-fold activity difference was observed for these azopyridine-imidacloprids against house fly (Musca domestica) and cowpea aphid (Aphis craccivora) upon irradiation. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cclet.2016.03.033

文献信息

• Das, Mrinal Kanti; Bandyopadhyay, Soumendra Nath, Journal of Chemical Research - Part S
  作者：Das, Mrinal Kanti、Bandyopadhyay, Soumendra Nath

  DOI：——

  日期：——
• Azopyridine-imidacloprid derivatives as photoresponsive neonicotinoids
  作者：Shen Li、Run-Jiang Song、Dong-Hui Wang、Xue Tian、Xu-Sheng Shao、Zhong Li

  DOI：10.1016/j.cclet.2016.03.033

  日期：2016.5

  A series of imidacloprid derivatives containing an azopyridine motif as a photoswitchable functional group were designed and synthesized. The new version of photoresponsive imidacloprid analogues showed improved solubility in comparison with their azobenzene analogues. 1.2 to 2-fold activity difference was observed for these azopyridine-imidacloprids against house fly (Musca domestica) and cowpea aphid (Aphis craccivora) upon irradiation. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.