1-bis[4-[(E)-hex-1-enyl]phenyl]phosphoryl-4-[(E)-hex-1-enyl]benzene | 661451-75-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-bis[4-[(E)-hex-1-enyl]phenyl]phosphoryl-4-[(E)-hex-1-enyl]benzene
• CAS: 661451-75-8
• 化学式: C₃₆H₄₅OP
• 分子量: 524.726
• InChiKey: VCSBVKOAJOCCEX-NLCRRHETSA-N

物化性质

• 沸点：
  673.3±55.0 °C(Predicted)
• 密度：
  1.03±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  11.6
• 重原子数：
  38
• 可旋转键数：
  15
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-bis[4-[(E)-hex-1-enyl]phenyl]phosphoryl-4-[(E)-hex-1-enyl]benzene 在 palladium on activated charcoal 三氯硅烷 、 氢气 、 三乙胺 作用下， 以 乙酸乙酯 、 甲苯 为溶剂， 20.0~120.0 ℃ 、1.0 MPa 条件下， 反应 10.0h， 生成 Tris-(4-n-hexylphenyl)phosphin
  参考文献：
  名称：

  Palladium-Catalyzed Synthesis of Aqueous, Fluorous, and Supercritical CO₂-Soluble Phosphines

  摘要：

  [GRAPHICS]A generic, simple, and economical route has been developed for the synthesis of phosphines soluble in aqueous, fluorous, and supercritical CO2 phases. The methodology is based on the palladium-catalyzed Heck olefination of haloary/phosphine oxides followed by reduction, affording various arylphosphines in high yields.

  DOI：

  10.1021/ol006203+
• 作为产物：
  描述：

  1-己烯 、 tris(4-bromophenyl)phosphine oxide 在 trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) sodium acetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以91%的产率得到1-bis[4-[(E)-hex-1-enyl]phenyl]phosphoryl-4-[(E)-hex-1-enyl]benzene
  参考文献：
  名称：

  Palladium-Catalyzed Synthesis of Aqueous, Fluorous, and Supercritical CO₂-Soluble Phosphines

  摘要：

  [GRAPHICS]A generic, simple, and economical route has been developed for the synthesis of phosphines soluble in aqueous, fluorous, and supercritical CO2 phases. The methodology is based on the palladium-catalyzed Heck olefination of haloary/phosphine oxides followed by reduction, affording various arylphosphines in high yields.

  DOI：

  10.1021/ol006203+

文献信息

• Method of generating a functionalised arylphosphine
  申请人：——

  公开号：US20030181767A1

  公开（公告）日：2003-09-25

  A method of generating a functionalised arylphosphine, novel intermediates and novel functionalised arylphosphines.

  生成官能化芳基膦的方法，新型中间体和新型官能化芳基膦。
• A Method of Generating A Functionalised Arylphosphine
  申请人：The University of Liverpool

  公开号：US20040059159A2

  公开（公告）日：2004-03-25

  Abstract of the Disclosure A method of generating a functionalised arylphosphine, novel intermediates and novel functinalised arylphosphines.

  本发明涉及一种生成功能化芳基膦、新型中间体和新型功能化芳基膦的方法。
• A METHOD OF GENERATING A FUNCTIONALISED ARYLPHOSPHINE
  申请人：THE UNIVERSITY OF LIVERPOOL

  公开号：EP1250341A1

  公开（公告）日：2002-10-23
• [EN] A METHOD OF GENERATING A FUNCTIONALISED ARYLPHOSPHINE<br/>[FR] PROCEDE DE PRODUCTION D'UNE ARYLPHOSPHINE FONCTIONNALISEE
  申请人：UNIV LIVERPOOL

  公开号：WO2001055156A1

  公开（公告）日：2001-08-02

  A method of generating a functionalised arylphosphine, novel intermediates and novel functionalised arylphosphines.
• Palladium-Catalyzed Synthesis of Aqueous, Fluorous, and Supercritical CO₂-Soluble Phosphines
  作者：Weiping Chen、Lijin Xu、Jianliang Xiao

  DOI：10.1021/ol006203+

  日期：2000.8.1

  [GRAPHICS]A generic, simple, and economical route has been developed for the synthesis of phosphines soluble in aqueous, fluorous, and supercritical CO2 phases. The methodology is based on the palladium-catalyzed Heck olefination of haloary/phosphine oxides followed by reduction, affording various arylphosphines in high yields.