cis-{Pt(DMSO)(py)Cl2} | 22872-01-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: cis-{Pt(DMSO)(py)Cl2}
• 英文别名: cis-[PtCl2(C5H5N)(Me2SO)]；cis-[Pt(C5H5N)(Me2SO)Cl2]；cis-[Pt(pyridine)Cl2(dimethylsulfoxide)]；cis-[Pt(Py)(DMSO)Cl2]；methylsulfinylmethane;platinum(2+);pyridine;dichloride
• CAS: 22872-01-1
• 化学式: C₇H₁₁Cl₂NOPtS
• 分子量: 423.222
• InChiKey: MEFCRHRAIOOMDT-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.92
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  49.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  cis-{Pt(DMSO)(py)Cl2} 在 氯 作用下， 以 氯仿 为溶剂， 生成 cis-{Pt(dimethyl sulfoxide)(pyridine)Cl4}
  参考文献：
  名称：

  Kukishkin, V. Yu.; Moiseev, A. I.; Sidorov, E. O., Journal of general chemistry of the USSR, 1989, vol. 59, p. 1750 - 1759

  摘要：

  DOI：
• 作为产物：
  描述：

  cis-dichlorobis(dimethylsulfoxide)platinum(II) 在 吡啶 作用下， 以 乙二醇二甲醚 为溶剂， 生成 cis-{Pt(DMSO)(py)Cl2}
  参考文献：
  名称：

  Kinetics of displacement of dimethyl sulfoxide from cis-dichlorobis(dimethyl sulfoxide)platinum(II) by amines in dimethoxyethane

  摘要：

  DOI：

  10.1021/ic50219a032
• 作为试剂：
  描述：

  甲基二氯硅烷 、 苯基-(1-苯亚乙基)胺 在 cis-{Pt(DMSO)(py)Cl2} 作用下， 生成 (Dichloro-methyl-silanyl)-phenyl-(1-phenyl-ethyl)-amine
  参考文献：
  名称：

  Hydrosilylation of Aromatic Azomethines

  摘要：

  The reactions of aromatic azomethines with methyldichlorosilane, phenyldichlorosilane, and dimethylchlorosilane, performed in the presence of Speier's, Wilkinson's, and Karstedt's catalysts and a series of P(II) complexes LL'PtCl2, give hydrosilylation and reduction products whose ratio depends on the catalyst used. The hi-hest yield of hydrosilylation products is attained with Pt(II) complexes as catalysts.

  DOI：

  10.1023/b:rugc.0000031855.77108.f6

文献信息

• Nucleophilic discrimination and the trans effect. The kinetics of displacement of X from trans-[Pt(L)(X)Cl2] n? (L = Me2SO, Et2S, PMe3, PEt3, PPh3, or AsEt3; X = Cl, n= 1; X = MeOH, n= 0) by neutral and anionic nucleophiles
  作者：Martin L. Tobe、Andrew T. Treadgold、Lucio Cattalini

  DOI：10.1039/dt9880002347

  日期：——

  The kinetics of the reaction trans-[Pt(L)(X)Cl2]n–+ L′→trans-[Pt(L)(L′)Cl2]n′–+ X (X = Cl–, n= 1, L = Me2SO, Et2S, PMe3, PEt3, PPh3, or AsEt3, L′= pyridine (py), Me2S, Et2S, PPh3, Me2SO, thiourea (tu), or NNN′N′-tetramethylthiourea (tmtu), n′= 0; L′= Cl–, Br–, I–, or SCN–, n′= 1; X = MeOH, n= 0, L′= Cl–, Br–, I–, or SCN–, n′= 1) have been studied in 95% methanol + 5% water at 25 °C. The second-order

  该反应的动力学反式- [铂（L）（X）氯2 ]正+ L'→反式- [铂（L）（L'）氯2 ] -N' - + X（X =氯- ，Ñ = 1，L =我2 SO，等2 S，PME 3，宠物3，PPH 3，或ASET 3，L'=吡啶（PY）中，Me 2 S，等2 S，PPH 3中，Me 2 SO，硫脲（TU），或NNN ' ñ '-tetramethylthiourea（tmtu），ñ '= 0; L'=氯-，溴-，I –或SCN –，n '= 1；X = MeOH，n = 0，L'= Cl –，Br –，I –或SCN –，n '= 1）已在25％的95％甲醇+ 5％水中进行了研究。阴离子底物的二级速率常数k 2不遵循通常的依赖关系，即n 0 Pt'，阴离子亲核试剂的反应性比预期的要小得多。基于[Pt（Et 3 As）Cl 3 ]的新亲核标度–作为标准底物，确实给出了所有阴离子底物的线性关系。
• Synthesis, Characterization, and Reactivity of <i>trans</i>-[PtCl(R‘R‘ ‘SO)(A)₂]NO₃ (R‘R‘ ‘SO = Me₂SO, MeBzSO, MePhSO; A = NH₃, py, pic). Crystal Structure of <i>trans</i>-[PtCl(Me₂SO)(py)₂]⁺
  作者：Ana P. S. Fontes、Åke Oskarsson、Karin Lövqvist、Nicholas Farrell

  DOI：10.1021/ic000107n

  日期：2001.4.1

  4-methylpyridine or picoline (pic)) were prepared for comparison of the chemical reactivity between ammine and pyridine ligands. The X-ray crystal structure determination for trans-[PtCl(Me(2)SO)(py)(2)]NO(3) confirmed the geometry with S-bound Me(2)SO. The crystals are orthorhombic, space group P2(1)2(1)2(1), with cell dimensions a = 7.888(2) A, b = 14.740(3) A, c =15.626(5) A, and Z = 4. The geometry

  反式复合物，例如反式-[PtCl（2）（NH（3））（2）]在历史上一直被认为是无治疗活性的。平面配体如吡啶的使用大大增强了反式几何结构的细胞毒性。反式-[PtCl（R'R''SO）（A）（2）] NO（3）（R'R''SO =取代的亚砜，例如二甲基（Me（2）SO），甲基苄基（MeBzSO ）和甲基苯基亚砜（MePhSO）和A = NH（3），吡啶（py）和4-甲基吡啶或甲基吡啶（pic））的制备，用于比较胺和吡啶配体之间的化学反应性。反式-[PtCl（Me（2）SO）（py）（2）] NO（3）的X射线晶体结构测定证实了S结合的Me（2）SO的几何结构。晶体是正交晶体，空间群P2（1）2（1）2（1），晶胞尺寸为a = 7.888（2）A，b = 14.740（3）A，c = 15.626（5）A和Z = 4。铂原子周围的几何形状为正方形平面，l（Pt-Cl）= 2.304（4）A，l（Pt-S）=
• Interaction of pyridineplatinum(II) complexes with alkyl sulfoxides
  作者：D. A. de Vekki

  DOI：10.1134/s0036023608080159

  日期：2008.8

  Interaction of pyridineplatinum(II) complexes with dimethyl sulfoxide and diethyl sulfoxide is studied by NMR spectroscopy. The interaction products are pyridinesulfoxide and bissulfoxide platinum(II) complexes. Cis-trans isomerization of the products is observed along with the substitution reaction and determines the final configuration of the complexes.
• ——
  作者：D. A. de Vekki、V. N. Spevak、N. K. Skvortsov

  DOI：10.1023/a:1011357929566

  日期：——

  The reactions of the optically active geometric isomers of the platinum(II) complex (-)-[Pt(Me-p-TolSO)(Py)Cl-2] with several nucleophilic reagents (Py, Ph3PS, Ph3P, Ph3As, and Me2SO) were studied by optical rotatory dispersion, IR spectroscopy, and H-1 and P-31 NMR spectroscopy. A mechanism for the reaction is proposed.
• Kukushkin, V. Yu.; Bel'skii, V. K.; Aleksandrova, E. A., Journal of general chemistry of the USSR, 1991, vol. 61, p. 284 - 293
  作者：Kukushkin, V. Yu.、Bel'skii, V. K.、Aleksandrova, E. A.、Pan'kova, E. Yu.、Konovalov, V. E.、et al.

  DOI：——

  日期：——