(E,E,E)-10,12,14-Hexadecatrienal

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E,E,E)-10,12,14-Hexadecatrienal
• 英文别名: (10E,12E,14E)-Hexadeca-10,12,14-trienal；(E10,E12,E14)-Hexadeca-10,12,14-trienal；10E,12E,14E-Hexadecatrienal
• 化学式: C₁₆H₂₆O
• 分子量: 234.382
• InChiKey: QXMRYABYXKUWCX-ICDJNDDTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  17
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,10-癸二醇 在 吡啶 、 甲醇 、 4-二甲氨基吡啶 、 正丁基锂 、 草酰氯 、 potassium carbonate 、 二甲基亚砜 、 三乙胺 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 为溶剂， 反应 24.01h， 生成 (E,E,E)-10,12,14-Hexadecatrienal
  参考文献：
  名称：

  Preparative Scale Syntheses of Isomerically Pure (10E,12E,14Z)- and (10E,12E,14E)-Hexadeca-10,12,14-trienals, Sex Pheromone Components of Manduca sexta

  摘要：

  已开发出简短、有效的合成方法，能够获得具有很高异构体纯度的产品，包括烟草角虫蛾（Manduca sexta）的关键信息素成分（10E,12E,14E）-十六烯-10,12,14-醛1和（10E,12E,14Z）-异构体2。倒数第二步的（EEZ）-三烯醇和醛1通过与四氰乙烯的选择性反应去除了异构体杂质。通过将（2E,4E）-六烯-2,4-二烯基三苯基磷盐溴化物与10-乙酰氧基十醛进行Wittig反应，去保护，选择性结晶从结果异构体混合物中得到（EEE）-三烯醇，并进行氧化，制得（EEE）-醛2。通过对混合异构体的碘催化异构化和进一步再结晶，进一步提高了（EEE）-三烯醇的产率。

  DOI：

  10.1055/s-2000-6227

文献信息

• AGRICULTURAL PHEROMONE COMPOSITIONS COMPRISING POSITIONAL ISOMERS
  申请人：PROVIVI, INC.

  公开号：US20170135343A1

  公开（公告）日：2017-05-18

  The present disclosure provides pheromone compositions. In some aspects, the compositions taught herein comprise a pheromone chemically corresponding to the pheromone naturally produced by a given insect, along with at least one positional isomer of said pheromone. In various aspects, pheromone compositions of the present disclosure are able to modulate the response of the insect based on the ratio of natural pheromone to its positional isomer.

  本公开提供信息素组合物。在某些方面，本文所教授的组合物包括一种与某种昆虫自然产生的信息素在化学上相对应的信息素，以及至少一种该信息素的位置异构体。在各个方面，本公开的信息素组合物能够通过自然信息素与其位置异构体的比例来调节昆虫的反应。
• Biodegradable sustained-release preparation, biodegradable pheromone dispenser and biodegradable pest controlling agent
  申请人：RESEARCH ASSOCIATION FOR BIOTECHNOLOGY OF AGRICULTURAL CHEMICALS

  公开号：EP0816430A2

  公开（公告）日：1998-01-07

  Described are a biodegradable sustained-release preparation which comprises a mixture of 99 to 10 parts by weight of an aliphatic polyester and 1 to 90 parts by weight of a modifier for the regulation of sustained releasability of an active ingredient, and the active ingredient held by said mixture; a biodegradable pheromone dispenser, wherein an aliphatic polyester is used as a sustained release layer for a pheromone contained therein as a liquid phase, said aliphatic polyester having recurring units whose ratio (I/II) of (I) the number of the carbon atoms constituting the main chain and not relating to ester linkage to (II) the number of the carbon atoms constituting the ester linkage is 2 or larger; and a biodegradable pest controlling agent which is obtained by mixing and dispersing an active ingredient and a carrier for holding said active ingredient in a biodegradable aliphatic polyester or which comprises 2 to 60 wt.% of an active ingredient, 30 to 95 wt.% of a biodegradable aliphatic polyester and 2 to 50 wt.% of a carrier for holding the active ingredient.

  描述了一种可生物降解的缓释制剂，它包括按重量计 99 至 10 份脂肪族聚酯和按重量计 1 至 90 份用于调节活性成分缓释性的改性剂的混合物，以及由所述混合物保持的活性成分；一种可生物降解的信息素分配器，其中脂肪族聚酯用作其中所含信息素的液相持续释放层，所述脂肪族聚酯具有重复单元，其(I/II)比率为(I)构成主链且与酯连接无关的碳原子数与(II)构成酯连接的碳原子数之比为 2 或更大；一种可生物降解的害虫控制剂，它是通过将一种活性成分和一种用于保持所述活性成分的载体混合并分散在一种可生物降解的脂肪族聚酯中而得到的，或者它包括 2 至 60 wt.%的活性成分、30-95%的可生物降解脂肪族聚酯和2-50%的用于保持活性成分的载体。
• Microcapsule and production method thereof
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：EP1421989A1

  公开（公告）日：2004-05-26

  Provided are a microcapsule and a production method thereof using a low-toxicity polymer substrate which can be produced regardless of a core material's water or oil solubility, without using gelatin or an organic solvent viewed as having a problem with safety. Specifically, provided is a microcapsule comprising oil-based core material which is immiscible with water; and shell material which comprises gum arabic and an enteric anionic cellulose derivative. Also provided is a method for producing a microcapsule comprising steps of suspending an oil-based water-immiscible core material in an aqueous solution of gum arabic, and then adding an aqueous alkaline solution of an enteric anionic cellulose derivative.

  本发明提供了一种微胶囊及其生产方法，该方法使用低毒性聚合物基材，无论芯材的水溶性或油溶性如何，均可生产，无需使用明胶或被视为存在安全问题的有机溶剂。具体地说，本发明提供了一种微胶囊，包括与水不相溶的油基核心材料；以及由阿拉伯树胶和肠道阴离子纤维素衍生物组成的外壳材料。还提供了一种生产微胶囊的方法，包括以下步骤：将油基不溶于水的芯材悬浮在阿拉伯树胶的水溶液中，然后加入肠阴离子纤维素衍生物的碱性水溶液。
• Biodegradeable sustained release pest controlling agent
  申请人：RESEARCH ASSOCIATION FOR BIOTECHNOLOGY OF AGRICULTURAL CHEMICALS

  公开号：EP1493332A1

  公开（公告）日：2005-01-05

  Described is a biodegradable pest controlling agent which is obtained by mixing and dispersing an active ingredient and a carrier for holding said active ingredient in a biodegradable aliphatic polyester or which comprises 2 to 60 wt.% of an active ingredient, 30 to 95 wt.% of a biodegradable aliphatic polyester and 2 to 50 wt.% of a carrier for holding the active ingredient.

  所描述的是一种可生物降解的害虫控制剂，它是通过将活性成分和用于保持所述活性成分的载体混合并分散在可生物降解的脂肪族聚酯中获得的，或由 2 至 60 重量份的活性成分、30 至 95 重量份的可生物降解的脂肪族聚酯和 2 至 50 重量份的用于保持活性成分的载体组成。
• MULTI-SUBSTRATE METABOLISM FOR IMPROVING BIOMASS AND LIPID PRODUCTION
  申请人：Provivi, Inc.

  公开号：EP3564377A1

  公开（公告）日：2019-11-06

  The present application relates to methods to improve biomass or lipid production in a microorganism from one or more fatty acid and one or more simple carbon co-substrates. Produced lipids may include unsaturated C6-C24 fatty acids, alcohols, aldehydes, and acetates which may be useful as final products or precursors to insect pheromones, fragrances, flavors, and polymer intermediates. The application further relates to recombinant microorganisms modified for improved production of biomass or lipid, or improved lipid selectivity. Also provided are methods of producing one or more lipid using the recombinant microorganisms, as well as compositions comprising the recombinant microorganisms and/or optionally one or more of the product lipid.

  本申请涉及提高微生物中一种或多种脂肪酸和一种或多种单碳共底物的生物量或脂质产量的方法。生产的脂质可包括不饱和 C6-C24 脂肪酸、醇、醛和乙酸酯，它们可用作昆虫信息素、香料、香精和聚合物中间体的最终产品或前体。本申请还涉及为改进生物质或脂质的生产或改进脂质选择性而改良的重组微生物。还提供了使用重组微生物生产一种或多种脂质的方法，以及包含重组微生物和/或一种或多种产品脂质的组合物。