arachidonoylethyleneglycol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: arachidonoylethyleneglycol
• 英文别名: Virodhamine；(5Z,8Z,11Z)-Icosa-5,8,11,14-tetraenoic acid 2-hydroxy-ethyl ester；2-hydroxyethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
• 化学式: C₂₂H₃₆O₃
• 分子量: 348.526
• InChiKey: ZWXLHTWQEHZSAD-DOFZRALJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  25
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  花生四烯酸 在 吡啶 、 4-二甲氨基吡啶 、 三聚氟氰 作用下， 以 乙腈 为溶剂， 反应 13.0h， 生成 arachidonoylethyleneglycol
  参考文献：
  名称：

  Bezuglov; Bobrov; Gretskaya, Russian Journal of Bioorganic Chemistry, 1998, vol. 24, # 12, p. 833 - 836

  摘要：

  DOI：

文献信息

• OZONOLYSIS REACTIONS IN LIQUID CO2 AND CO2-EXPANDED SOLVENTS
  申请人：University Of Kansas

  公开号：EP2209547A2

  公开（公告）日：2010-07-28
• Treatment of neurodegenerative conditions
  申请人：Harbige Lawrence S.

  公开号：US20100113595A1

  公开（公告）日：2010-05-06

  A method is provided for treating a patient in need of therapy for a neurodegenerative disease comprising administering to that patient a therapeutically effective dose of a lipid glyceride comprising a glycerol moiety and a fatty acid moiety, the fatty acid moiety being selected from the group consisting of γ-linolenic acid, dihomo-γ-linolenic acid and arachidonic acid characterised in that the selected fatty acid moiety is attached to the glycerol moiety at its sn-2 position. Preferably the method is that wherein the lipid is administered for a duration and at a dose sufficient to maintain or elevate TGF-β1 levels in the patient to therapeutic levels.
• Ozonolysis Reactions in Liquid CO2 and CO2-Expanded Solvents
  申请人：UNIVERSITY OF KANSAS

  公开号：US20130240781A1

  公开（公告）日：2013-09-19

  A method for increasing ozone concentration in a liquid can include: providing a gas having ozone; introducing the ozone-containing gas into a liquid, wherein the liquid and ozone combination has a temperature between about 0.8 and about 1.5 times the critical temperature of ozone; and increasing isothermally, the pressure of the ozone-containing gas above the liquid to about 0.3 to about 5 times the critical pressure of ozone so as to increase the ozone concentration in the liquid. The temperature is expressed in absolute units (Kelvin or Rankin). The method can be used for removing ozone from a gas or for purifying ozone. The liquid having a high ozone concentration can be used for ozonolysis of a substrate.
• US4364743A
  申请人：——

  公开号：US4364743A

  公开（公告）日：1982-12-21
• US8425784B2
  申请人：——

  公开号：US8425784B2

  公开（公告）日：2013-04-23