1,3,4,4-Trichlorotetrafluoro-1-butene | 357-20-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 英文名称: 1,3,4,4-Trichlorotetrafluoro-1-butene
• 英文别名: 1,3,4,4-tetrachloro-1,2,3,4-tetrafluoro-but-1-ene；1,3,4,4-Tetrachlor-1,2,3,4-tetrafluor-but-1-en；1,2,3,4-Tetrafluor-1,3,4,4-tetrachlor-buten-(1)；(+,-)-1,3,4,4-Tetrachloro-1,2,3,4-tetrafluoro-1-butene；1,3,4,4-tetrachloro-1,2,3,4-tetrafluorobut-1-ene
• CAS: 357-20-0
• 化学式: C₄Cl₄F₄
• 分子量: 265.85
• InChiKey: CYLIGQKNBPAGBL-UHFFFAOYSA-N

物化性质

• 沸点：
  140.8°C (rough estimate)
• 密度：
  1.6902

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,3,4,4-Trichlorotetrafluoro-1-butene 在 氯 作用下， 生成 1,2,3,4-tetrafluoro-1,1,2,3,4,4-hexachlorobutane
  参考文献：
  名称：

  Preparation of hexafluorobutadiene from symmetrical dichlorodifluoroethylene

  摘要：

  公开号：

  US02777004A1
• 作为产物：
  描述：

  1,2-二氯-1,2-二氟乙烯 生成 1,3,4,4-Trichlorotetrafluoro-1-butene
  参考文献：
  名称：

  Invasive fungal sinusitis in the acquired immunodeficiency syndrome

  摘要：

  Invasive fungal sinusitis can present as either an indolent or fulminant process that primarily affects immunocompromised individuals. In this article, the clinical characteristics of four cases of invasive fungal sinusitis in patients with AIDS are analyzed and 22 additional previously reported cases in the literature are reviewed. In addition to HIV infection, other variables common to these cases include facial pain or headache out of proportion to clinical or radiographic findings, CD4 lymphocyte count less than 50 cells/mm(3), absolute neutrophil count less than 1,000 cells/mm(3), subtle radiographic evidence suggesting invasion and an indolent clinical course of the invasive infection. The most common pathogen detected was Aspergillus fumigatus. Maintaining a high index of suspicion, critically assessing these clinical findings, and prudently reviewing CT scans may facilitate early diagnosis and prompt intervention in these patients.

  DOI：

  10.1016/s0030-6665(00)80009-2

文献信息

• Reductive coupling of polyfluorovinyl halides in the presence of copper-bronze
  作者：G. Camaggi、S.F. Campbell、D.R.A. Perry、R. Stephens、J.C. Tatlow

  DOI：10.1016/s0040-4020(01)82247-x

  日期：1966.1

  1-bromononafluorocyclohexeneand 1-bromoheptafluorocyclopentene undergo reductive coupling reactions when heated with copper bronze to give 1,4-dichlorotetrafluorobuta-1,3-diene and perfluorobicyclo-hex-1,1′-enyl and -pent-1,1′-enyl, respectively. The same olefins undergo crossed coupling reactions with phenyl and pentafluorophenyl halides and, in the first case, with 1-iodoheptafluoropropane.

  1-氯-1,2-二氟碘乙烯，1-溴氟氟环己烯和1-溴庚基氟环戊烯与铜青铜一起加热时会发生还原偶联反应，从而得到1,4-二氯四氟丁-1,3-二烯和全氟双环-hex-1,1'-烯基和-pent-1,1'-enyl。相同的烯烃与苯基和五氟苯基卤化物进行交叉偶联反应，在第一种情况下与1-碘七氟丙烷进行交叉偶联反应。
• Reactions of fluoro olefins
  作者：I. L. Knunyants、B. L. Dyatkin、L. S. German、E. P. Mochalina

  DOI：10.1007/bf00942892

  日期：1960.2
• DE856145
  申请人：——

  公开号：——

  公开（公告）日：——
• Zemlyanskaya, N. V.; Volkov, G. V.; Barabanov, V. G., Journal of general chemistry of the USSR, 1989, vol. 59, # 3.2, p. 551 - 558
  作者：Zemlyanskaya, N. V.、Volkov, G. V.、Barabanov, V. G.、Zenkevich, I. G.、V'yunov, K. A.

  DOI：——

  日期：——
• 1,2-dibromo-1,3,4,4-tetrachloro-1,2,3,4-tetrafluorobutane
  申请人：DOW CHEMICAL CO

  公开号：US02676193A1

  公开（公告）日：1954-04-20