N,N''-双十二烷基硫代脲 | 7505-51-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫脲类
• 中文名称: N,N''-双十二烷基硫代脲
• 英文名称: 1,3-didodecylthiourea
• 英文别名: Dilaurylthiourea；N,N'-didodecyl-thiourea；N,N'-Didodecyl-thioharnstoff；1,3-didodecyl-2-thiourea；N,N'-didodecylthiourea；N,N'-Didodecylthioharnstoff；Thiourea, N,N'-didodecyl-
• CAS: 7505-51-3
• 化学式: C₂₅H₅₂N₂S
• 分子量: 412.767
• InChiKey: NWFVONWTBGQHGT-UHFFFAOYSA-N

物化性质

• 熔点：
  76-77 °C
• 沸点：
  493.6±28.0 °C(Predicted)
• 密度：
  0.889±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  28
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  56.2
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N''-双十二烷基硫代脲 在 一水合肼 作用下， 反应 2.0h， 生成 N'-Amino-N.N'-didodecyl-guanidin
  参考文献：
  名称：

  抑菌剂。VI。某些取代胍类的抑菌活性。

  摘要：

  DOI：

  10.1021/jm00341a028
• 作为产物：
  描述：

  1,3,5-tridodecylperhydro-1,3,5-triazine 在 吡啶 、 sulfur 作用下， 生成 N,N''-双十二烷基硫代脲
  参考文献：
  名称：

  Notes: Action of Sulfur on Primary Amine-Formaldehyde Condensates

  摘要：

  DOI：

  10.1021/jo01091a629

文献信息

• Green Process Development for the Synthesis of Aliphatic Symmetrical <i>N,N′</i>-Disubstituted Thiourea Derivatives in Aqueous Medium
  作者：Asha D. Jangale、Priyanka P. Kumavat、Yogesh B. Wagh、Yogesh A. Tayade、Pramod P. Mahulikar、Dipak S. Dalal

  DOI：10.1080/00397911.2014.960939

  日期：2015.1.17

  Abstract A highly efficient green process for the synthesis of N,N′-disubstituted aliphatic thiourea derivatives using primary aliphatic amines and carbon disulfide in aqueous medium at room temperature via a nonisothiocyanate route is described. This protocol illustrates the rapid preparation of N,N′-disubstituted aliphatic thiourea derivatives in excellent yields with some advantages such as no catalyst

  摘要 描述了一种在室温下，在水性介质中，通过非异硫氰酸酯路线，使用脂肪伯胺和二硫化碳合成 N,N'-二取代脂肪族硫脲衍生物的高效绿色工艺。该协议说明了以优异的收率快速制备 N,N'-二取代脂肪族硫脲衍生物, 具有一些优点, 如无催化剂和简单的后处理, 没有任何副产物形成。此外，新路线简洁，无需色谱，适用于中试制备。图形概要
• FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS
  申请人：Peretolchin Maxim

  公开号：US20120252987A1

  公开（公告）日：2012-10-04

  The present invention relates to a method for producing amphiphilic functionalized highly branched melamine-polyamine polymers by condensing melamine and optionally a melamine derivate having at least one different amine having at least two primary amino groups and optionally also with urea and/or at least one urea derivative and/or with at least one at least difunctional diisocyanate or polyisocyanate and/or at least one carbolic acid having at least two carboxyl groups or at least one derivative thereof, optionally quaternizing a portion of the amino groups of the polymer thereby obtained, reacting the polymer thus obtained with at least one compound capable of undergoing a condensation or addition reaction with amino groups, and optionally quaternizing at least part of the amino groups of the polymer obtained in the first step. The invention further relates to the amphiphilic functionalized highly branched melamine-polyamine polymers that can be obtained by the method according to the invention, and to the use thereof as surface active agents.

  本发明涉及一种通过将三聚氰胺和至少一种具有至少两个主要氨基的不同氨基的三聚氰胺衍生物以及可能还包括尿素和/或至少一种尿素衍生物和/或至少一种至少双官能团二异氰酸酯或多异氰酸酯和/或至少一种至少具有两个羧基的羧酸或其衍生物缩合，从而制备含有两性功能化的高支化三聚氰胺-多胺聚合物的方法。可选地，对所获得的聚合物的部分氨基进行季铵化，然后将所获得的聚合物与至少一种能够与氨基发生缩合或加成反应的化合物反应，并可选地对第一步中获得的聚合物的部分氨基进行季铵化。本发明还涉及通过本发明的方法可以获得的含有两性功能化的高支化三聚氰胺-多胺聚合物，以及将其用作表面活性剂的用途。
• [3-substituted-2-(substituted imino)-4-oxo-5-thiazolidinylidene]acetic
  申请人：Warner-Lambert Company

  公开号：US04775677A1

  公开（公告）日：1988-10-04

  The present invention provides novel [3-substituted-2-(substituted imino)-4-oxo-5-thiazolidinylidene]acetic acids, and novel pharmaceutical compositions and methods of use thereof. The novel acids of the invention are leukotriene antagonists having activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and inflammation.

  本发明提供了新颖的[3-取代-2-(取代亚胺)-4-氧代-5-噻唑烯基]乙酸，以及新颖的药物组合物和使用方法。该发明的新颖酸是白三烯拮抗剂，具有用于治疗哮喘、过敏、心血管疾病、偏头痛和炎症的活性。
• Thermoplastic resin composition and elastomer composition
  申请人：——

  公开号：US20040106732A1

  公开（公告）日：2004-06-03

  Provided are a thermoplastic resin composition which is excellent in oil resistance, heat resistance, weatherability, impact resistance, transparency, and moldability, and which can be produced economically, an elastomer composition with low hardness and high tensile strength which is excellent in oil resistance and compression set, and a molded object produced by molding the thermoplastic resin composition or elastomer composition. The composition is produced by compounding a thermoplastic resin or an elastomer with a block copolymer having at least one methacrylic ester polymer block and at least one acrylic ester polymer block. Also provided are a process for producing a methacrylic ester-acrylic ester-methacrylic ester block copolymer which requires hardly any purification, which is excellent in heat resistance and weatherability, and in which the molecular weight and the molecular-weight distribution are controlled, and a methacrylic ester-acrylic ester-methacrylic ester block copolymer produced by the process.

  提供了一种热塑性树脂组合物，具有优异的耐油性、耐热性、耐候性、抗冲击性、透明度和成型性，且可经济生产；一种低硬度、高拉伸强度的弹性体组合物，具有优异的耐油性和压缩回弹性；以及由该热塑性树脂组合物或弹性体组合物成型而成的成型物。该组合物通过将热塑性树脂或弹性体与至少具有一个甲基丙烯酸酯聚合物块和至少一个丙烯酸酯聚合物块的嵌段共聚物混合制备而成。 同时提供了一种制备甲基丙烯酸酯-丙烯酸酯-甲基丙烯酸酯嵌段共聚物的方法，该方法几乎不需要纯化，具有优异的耐热性和耐候性，并且分子量和分子量分布可控；以及由该方法制备的甲基丙烯酸酯-丙烯酸酯-甲基丙烯酸酯嵌段共聚物。
• Polymerizable composition, optical material comprising the composition and method for producing the material
  申请人：——

  公开号：US20040254258A1

  公开（公告）日：2004-12-16

  A cured matter obtained by polymerizing and curing a polymerizable composition comprising a compound having at least one episulfide in a molecule is reduced in an odor by adding a perfume to the polymerizable composition comprising the compound having at least one episulfide in a molecule. A cloudiness of the lens is removed by raising a purity of sulfur to 98% or more. A reduction in a chlorine content of the sulfur compound described above to 0.1% by weight or less elevates an oxidation resistance and a light fastness of the high refractive index optical material and improves a color tone thereof. An optical product having a high refractive index and a high-degree transparency is provided by subjecting the composition in advance to deaerating treatment at 0 to 100° C. for one minute to 24 hours under a reduced pressure of 0.001 to 50 torr.

  通过聚合和固化至少含有一种环硫醚的化合物的可聚合组合物获得的治愈物质，通过向至少含有一种环硫醚的化合物的可聚合组合物中添加香水来减少其气味。通过将硫的纯度提高到98％或更高，可以消除镜片的混浊。将上述硫化合物的氯含量降低至0.1％或更低可以提高高折射率光学材料的氧化抗性和耐光性，并改善其色调。通过在0至100°C下将组合物事先进行脱气处理，以在0.001至50 torr的减压下持续1分钟至24小时，可提供具有高折射率和高度透明度的光学产品。