4-(4-azido-β-methyl-cinnamylidene)-2-phenyl-2-oxazolin-5-one | 606142-91-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-(4-azido-β-methyl-cinnamylidene)-2-phenyl-2-oxazolin-5-one
• CAS: 606142-91-0
• 化学式: C₁₉H₁₄N₄O₂
• 分子量: 330.346
• InChiKey: HIRIXRUTSQRMRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.92
• 重原子数：
  25.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  87.42
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  4-(4-azido-β-methyl-cinnamylidene)-2-phenyl-2-oxazolin-5-one 、 4-氨基丁醛二甲缩醛 在 水 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 生成 5-(4-azidophenyl)-N-(4,4-dimethoxybutyl)-4-methyl-2-phenylcarbonylamino-penta-2,4-dienamide
  参考文献：
  名称：

  Novel cinnamaldehyde compound having an azido group

  摘要：

  这项发明提供了一种新型的偶氮肉桂醛化合物，当用作光阻的光敏基团的中间体时，引入了具有高灵敏度和在暴露部分与未暴露部分之间达到高对比度的光敏基团，并且本身可以作为光敏基团。偶氮肉桂醛化合物由式(I)表示：其中R代表低碳基团，Y代表氢或磺酸盐基团。

  公开号：

  US20030191329A1
• 作为产物：
  描述：

  马尿酸 、 p-azido-2-methylcinnamaldehyde 在 sodium acetate 、 乙酸酐 作用下， 以 甲苯 、 乙腈 为溶剂， 反应 40.0h， 生成 4-(4-azido-β-methyl-cinnamylidene)-2-phenyl-2-oxazolin-5-one
  参考文献：
  名称：

  Novel cinnamaldehyde compound having an azido group

  摘要：

  这项发明提供了一种新型的偶氮肉桂醛化合物，当用作光阻的光敏基团的中间体时，引入了具有高灵敏度和在暴露部分与未暴露部分之间达到高对比度的光敏基团，并且本身可以作为光敏基团。偶氮肉桂醛化合物由式(I)表示：其中R代表低碳基团，Y代表氢或磺酸盐基团。

  公开号：

  US20030191329A1

文献信息

• Cinnamaldehyde compound having an azido group
  申请人：Toyo Gosei Kogyo Co., Ltd.

  公开号：EP1348690A1

  公开（公告）日：2003-10-01

  The invention provides a novel azidocinnamaldehyde compound which, when used as an intermediate for providing a photosensitive moiety of a photoresist, introduces a photosensitive moiety having high sensitivity and attaining high contrast between the exposed portion and the unexposed portion, and which per se can serve as a photosensitive moiety. The azidocinnamaldehyde compound is represented by formula (I) : wherein R represents a lower alkyl group and Y represents hydrogen or a sulfonate salt group.

  本发明提供了一种新型叠氮肉桂醛化合物，该化合物用作提供光刻胶光敏分子的中间体时，可引入具有高灵敏度的光敏分子，并在曝光部分和未曝光部分之间实现高对比度，其本身可用作光敏分子。叠氮肉桂醛化合物由式 (I) ： 其中 R 代表低级烷基，Y 代表氢或磺酸盐基团。
• PHOTOSENSITIVE RESIN, PHOTOSENSITIVE COMPOSITION AND PHOTOCROSSLINKED ITEM
  申请人：TOYO GOSEI KOGYO CO., LTD.

  公开号：EP1865012A1

  公开（公告）日：2007-12-12

  The invention provides a photosensitive resin which can readily form, through photo-crosslinking, a surface coating which has hydrophilicity and high bioadaptability; a photosensitive composition containing the photosensitive resin; and a photo-crosslinked structure obtained from the photosensitive composition. The photosensitive resin is represented by the following formula (1): (wherein n represents a mean polymerization degree and is 5 or more; R1 and R2, which may be identical to or different from each other, each represent an alkylene group, an arylene group, an oxyalkylene group, or a single bond; each of X and Y represents a photosensitive unit represented by the following formula (2): or either one of X and Y represents a photosensitive unit represented by the above formula (2) and the other represents an amino group; R3 represents a group selected from among the groups represented by the following formula set (3): R4 represents a group selected from among the groups represented by the following formula set (4): at least one of R3 and R4 has at least one azido group; and R5 represents a hydrogen atom, an alkyl group, an acetal-group-containing alkyl group, an aryl group, an aralkyl group, or a substituent containing a base-forming nitrogen atom).

  本发明提供了一种通过光交联容易形成具有亲水性和高生物适应性的表面涂层的光敏树脂；一种含有该光敏树脂的光敏组合物；以及一种由该光敏组合物获得的光交联结构。 光敏树脂用下式（1）表示： (其中 n 代表平均聚合度，且为 5 或更多；R1 和 R2（它们可以彼此相同或不同）各自代表亚 烷基、芳烯基、氧烷基或单键；X 和 Y 各自代表由下式（2）表示的光敏单元： 或 X 和 Y 中的一个代表上式（2）所代表的光敏单元，另一个代表氨基； R3 代表从下式（3）所代表的基团中选出的一个基团： R4 代表从下式组 (4) 所代表的基团中选出的基团： R3 和 R4 中至少有一个具有至少一个叠氮基团；以及 R5 代表氢原子、烷基、含缩醛基团的烷基、芳基、芳烷基或含有形成碱基的氮原子的取代基）。
• METHOD OF PRODUCING CELL CULTURE CONTAINER
  申请人：Toyo Gosei Co., Ltd.

  公开号：EP2011857A1

  公开（公告）日：2009-01-07

  To produce a cell culture container which is suitable for use in, for example, biochemical experiments, clinical experiments, and research and development of drugs. The production of the cell culture container includes providing a cell culture container base 1 having a plurality of wells serving as regions for culturing cells; applying a hydrophilic photosensitive composition to the bottom surface of each of the wells, to thereby form a coating 3; subjecting the coating 3 to patternwise light exposure; and removing an uncured portion of the coating through development, to thereby yield a cell culture container having, on the bottom surface of each well, a patterned hydrophilic coating layer formed of a photo-cured product.

  生产一种适用于生化实验、临床实验和药物研发等用途的细胞培养容器。细胞培养容器的生产包括提供一个细胞培养容器底座 1，该底座具有多个作为细胞培养区域的孔；将亲水性光敏组合物涂在每个孔的底面上，从而形成涂层 3；将涂层 3 进行图案化光照射；通过显影去除涂层的未固化部分，从而得到一个细胞培养容器，该容器在每个孔的底面上具有由光固化产品形成的图案化亲水涂层层。
• NOVEL PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE RESIN, AND PHOTOSENSITIVE COMPOSITION
  申请人：——

  公开号：US20040266901A1

  公开（公告）日：2004-12-30

  The present invention provides a novel photosensitive compound having an azido group suitable for exposure to light of a short wavelength; a photosensitive resin containing the photosensitive compound; and a photosensitive composition containing the photosensitive compound or photosensitive resin. The photosensitive compound containing a photosensitive unit represented by formula (1): 1 wherein R is selected from among the following groups, 2 X is selected from among the following groups, 3 and each of Y and Z represents a hydrogen atom, an alkyl group, an acetal-group-containing alkyl group, an aryl group, an aralkyl group, or a substituent containing a base-forming nitrogen atom, wherein at least one of R and X contains an azido group.

  本发明提供了一种新型光敏化合物，该化合物具有适用于短波长光照射的叠氮基团；一种含有该光敏化合物的光敏树脂；以及一种含有该光敏化合物或光敏树脂的光敏组合物。该光敏化合物含有由式（1）表示的光敏单元： 1 其中 R 选自以下基团、 2 X 选自以下基团 3 Y 和 Z 分别代表氢原子、烷基、含缩醛基团的烷基、芳基、芳烷基或含有可形成碱基的氮原子的取代基，其中 R 和 X 中至少有一个含有叠氮基团。
• Photosensitive resin, photosensitive composition and photo-crosslinked structure
  申请人：Ikeya Takeshi

  公开号：US20060235103A1

  公开（公告）日：2006-10-19

  The invention provides a photosensitive resin which can readily form, through photo-crosslinking, a surface coating which has hydrophilicity and high bioadaptability; a photosensitive composition containing the photosensitive resin; and a photo-crosslinked structure obtained from the photosensitive composition. The photosensitive resin is represented by the following formula (1): (wherein n represents a mean polymerization degree and is 5 or more; R 1 and R 2 , which may be identical to or different from each other, each represent an alkylene group, an arylene group, an oxyalkylene group, or a single bond; each of X and Y represents a photosensitive unit represented by the following formula (2): or either one of X and Y represents a photosensitive unit represented by the above formula (2) and the other represents an amino group; R 3 represents a group selected from among the groups represented by the following formula set (3): R 4 represents a group selected from among the groups represented by the following formula set (4): at least one of R 3 and R 4 has at least one azido group; and R 5 represents a hydrogen atom, an alkyl group, an acetal-group-containing alkyl group, an aryl group, an aralkyl group, or a substituent containing a base-forming nitrogen atom).

  本发明提供了一种通过光交联容易形成具有亲水性和高生物适应性的表面涂层的光敏树脂；一种含有该光敏树脂的光敏组合物；以及一种由该光敏组合物获得的光交联结构。 光敏树脂用下式（1）表示： (其中 n 代表平均聚合度，为 5 或以上；R 1 和 R 2 可能相同，也可能不同，各自代表烯基、芳烯基、氧烷基或单键；X 和 Y 各自代表下式（2）所代表的光敏单元： 或 X 和 Y 中的一个代表上式（2）所代表的光敏单元，另一个代表氨基； R 3 代表从下式组 (3) 所代表的基团中选出的一个基团： R 4 代表从下式组 (4) 所代表的基团中选出的一个基团： R 3 和 R 4 至少有一个叠氮基团；以及 R 5 代表氢原子、烷基、含缩醛基团的烷基、芳基、芳烷基或含有可形成碱基的氮原子的取代基）。