N-2,3-dihydroxypropylalanine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-2,3-dihydroxypropylalanine
• 英文别名: 2-(2,3-Dihydroxypropylamino)propanoic acid
• 化学式: C₆H₁₃NO₄
• 分子量: 163.174
• InChiKey: WWTQSDRCSPZTCS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.8
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  89.8
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  缩水甘油 、 DL-丙氨酸 在 sodium hydroxide 、 盐酸 、 水 作用下， 以 水 为溶剂， 反应 6.0h， 生成 N-2,3-dihydroxypropylalanine
  参考文献：
  名称：

  EP1584320

  摘要：

  公开号：

文献信息

• COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE
  申请人：Seiwa Kasei Company, Limited

  公开号：EP1584320A1

  公开（公告）日：2005-10-12

  Skin care cosmetics, such as lotions, creams and milky lotions, and hair cosmetics, such as hair creams, hair conditioners, hair rinses and shampoos, being excellent in moisturizing effect, applicability, stability and safety and characterized in containing an amino acid N-glyceryl derivative produced by reacting neutral, basic or acidic α -amino acid or salt thereof with glycidol or 3-halo-1,2-propanediol.

  护肤化妆品，如乳液、面霜和乳状乳液，以及护发化妆品，如护发乳、护发素、洗发水和洗发香波，它们具有出色的保湿效果、适用性、稳定性和安全性，其特征在于含有一种氨基酸 N-甘油衍生物，该衍生物是由α-氨基酸或其盐与缩水甘油或 3-卤代-1,2-丙二醇反应生成的中性、碱性或酸性氨基酸。
• Oral and dental hygiene and cleaning products with an arginine derivative for improved plaque removal
  申请人：Henkel AG & Co. KGaA

  公开号：US10292919B2

  公开（公告）日：2019-05-21

  Oral and dental care and cleaning agents and methods that employ the agents are provided herein. In an embodiment, an oral and dental care and cleaning agent includes a polyol derivative of arginine. In another embodiment, a method includes the steps of supplying a toothbrush having a brush head and applying an agent to the brush head, wherein the agent includes a polyol derivative of arginine. Teeth are cleaned using the agent on the brush head.

  本文提供了口腔和牙齿护理清洁剂以及使用这些制剂的方法。在一个实施方案中，口腔和牙齿护理清洁剂包括精氨酸多元醇衍生物。在另一个实施方案中，一种方法包括以下步骤：提供具有刷头的牙刷，并在刷头上涂抹药剂，其中药剂包括精氨酸多元醇衍生物。使用刷头上的药剂清洁牙齿。
• Cosmetic preparation containing glycerylamino acid derivative
  申请人：Yoshioka Masato

  公开号：US20060018864A1

  公开（公告）日：2006-01-26

  Skin care cosmetics, such as lotions, creams and milky lotions, and hair cosmetics, such as hair creams, hair conditioners, hair rinses and shampoos, being excellent in moisturizing effect, applicability, stability and safety and characterized in containing an amino acid N-glyceryl derivative produced by reacting neutral, basic or acidic α-amino acid or salt thereof with glycidol or 3-halo-1,2-propanediol.

  护肤化妆品，如乳液、乳霜和乳状乳液，以及护发化妆品，如护发乳、护发素、洗发水和洗发香波，具有优异的保湿效果、适用性、稳定性和安全性，其特征在于含有一种氨基酸 N-甘油衍生物，该衍生物由中性、碱性或酸性 α-氨基酸或其盐与缩水甘油或 3-卤代-1,2-丙二醇反应生成。
• ORAL AND DENTAL HYGIENE AND CLEANING PRODUCTS WITH AN ARGININE DERIVATIVE FOR IMPROVED PLAQUE REMOVAL
  申请人：Henkel AG & Co. KGaA

  公开号：US20170326053A1

  公开（公告）日：2017-11-16

  Oral and dental care and cleaning agents and methods that employ the agents are provided herein. In an embodiment, an oral and dental care and cleaning agent includes a polyol derivative of arginine. In another embodiment, a method includes the steps of supplying a toothbrush having a brush head and applying an agent to the brush head, wherein the agent includes a polyol derivative of arginine. Teeth are cleaned using the agent on the brush head.
• DEHYDRATION AND AMINATION OF ALPHA-, BETA-DIHYDROXY CARBONYL COMPOUNDS TO ALPHA-AMINO ACIDS
  申请人：Archer Daniels Midland Company

  公开号：US20210163400A1

  公开（公告）日：2021-06-03

  Processes are disclosed for the synthesis of an α-amino acid or α-amino acid derivative, from a starting compound or substrate having a carbonyl functional group (C═O), with hydroxy-substituted carbon atoms at alpha (α) and beta (β) positions, relative to the carbonyl functional group. According a particular embodiment, an α-, β-dihydroxy carboxylic acid or carboxylate is dehydrated to form a dicarbonyl intermediate by transformation of the α-hydroxy group to a second carbonyl group (adjacent a carbonyl group of the starting compound) and removal of the β-hydroxy group. The dicarbonyl intermediate is optionally cracked to form a second, in this case cracked, dicarbonyl intermediate having fewer carbon atoms relative to the dicarbonyl intermediate but preserving the first and second carbonyl groups. Either or both of the dicarbonyl intermediate and the cracked dicarbonyl intermediate may be aminated to convert the second carbonyl group to an amino (—NH 2 ) group, for producing the corresponding α-amino acid(s).