N-(2-carboxyethyl)-o-aminobenzoic acid | 4395-58-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(2-carboxyethyl)-o-aminobenzoic acid
• 英文别名: N-(2-carboxyethyl)anthranilic acid；N-(2-carboxy-ethyl)-anthranilic acid；N-(2-Carboxy-aethyl)-anthranilsaeure；N-(2-Carboxy-phenyl)-β-alanin；2-[(2-Carboxyethyl)amino]benzoic acid；2-(2-carboxyethylamino)benzoic acid
• CAS: 4395-58-8
• 化学式: C₁₀H₁₁NO₄
• mdl: MFCD00767690
• 分子量: 209.202
• InChiKey: IMRIVMODOMQPRR-UHFFFAOYSA-N

物化性质

• 熔点：
  170 °C
• 沸点：
  482.3±30.0 °C(Predicted)
• 密度：
  1.403±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  86.6
• 氢给体数：
  3
• 氢受体数：
  5

安全信息

• 海关编码：
  2922499990

反应信息

• 作为反应物：
  描述：

  N-(2-carboxyethyl)-o-aminobenzoic acid 在 盐酸 作用下， 反应 8.08h， 生成 3-(3,4-dihydro-2,4-dioxoquinazolin-1(2H)-yl)propanoic acid
  参考文献：
  名称：

  1-取代的二氢嘧啶酮和喹唑啉酮衍生物的合成

  摘要：

  DOI：

  10.1007/bf00529585
• 作为产物：
  描述：

  2-氨基苯甲酸乙酯 在 sodium hydroxide 作用下， 生成 N-(2-carboxyethyl)-o-aminobenzoic acid
  参考文献：
  名称：

  Reaction of Propiolactone with Aniline Derivatives

  摘要：

  DOI：

  10.1021/ja01143a019

文献信息

• [EN] POLYMERIZABLE COMPOUNDS WITH QUADRUPLE HYDROGEN BOND FORMING GROUPS<br/>[FR] COMPOSES POLYMERISABLES AVEC GROUPES FORMANT DES LIAISONS HYDROGENE QUADRUPLES
  申请人：KODAK POLYCHROME GRAPHICS LLC

  公开号：WO2004043935A1

  公开（公告）日：2004-05-27

  QHB-Modified free radical polymerizable compounds and free radical polymerizable compositions that comprise these compounds are disclosed. A QBH-modified free radical polymerizable compound has at least one moiety that comprises at least one free radical polymerizable group; a supporting backbone, and at least one and preferably at least two moieties capable of forming four or more, typically four, hydrogen bonds with similar or complementary units on other molecules or portions of molecules. Free radical polymerizable compositions that contain these compounds may be used in any of the well-knows applications for free radical polymerizable compositions. They are especially useful for the formation of imageable elements useful as lithographic printing plate precursors.

  修改后的自由基可聚合化合物和包含这些化合物的自由基可聚合化组合物已被披露。一种QBH修饰的自由基可聚合化合物至少具有一个包含至少一个自由基可聚合基团的基团；一个支撑骨架，以及至少一个并且最好至少两个能够与其他分子或分子部分上的类似或互补单元形成四个或更多，通常为四个，氢键的基团。包含这些化合物的自由基可聚合化组合物可用于任何已知的自由基可聚合化组合物的应用中。它们特别适用于形成可用作平版印刷版前体的可成像元素。
• Copper(II) complexes with N-(2-carboxyethyl)anthranilic acid H2CEAnt. Synthesis and crystal structure of [Cu(CEAnt)(H2O)] ⋅ H2O
  作者：Yu. A. Skorik、E. V. Osintseva、N. V. Podberezskaya、A. V. Virovets、L. K. Neudachina、A. A. Vshivkov

  DOI：10.1007/s11172-006-0004-x

  日期：2005.7

  Protolytic equilibria and complexation of N-(2-carboxyethyl)anthranilic acid (H2CEAnt) with copper(II) ions in aqueous solutions were studied by UV spectroscopy and pH potentiometry. The H2CEAnt compound has no zwitterionic structure, and the protons are localized on the carboxy groups. The acid ionization constants of H3CEAnt+ (T = 25 °C, I = 0.1 M KNO3) are pK0 = 1.3±0.2 (=NH2+), pK1 = 3.88±0.02

  N-(2-羧乙基) 邻氨基苯甲酸 (H2CEAnt) 与铜 (II) 离子在水溶液中的质子分解平衡和络合通过紫外光谱和 pH 电位测定法进行研究。H2CEAnt 化合物没有两性离子结构，质子位于羧基上。H3CEAnt+ (T = 25 °C, I = 0.1 M KNO3) 的酸电离常数为 pK0 = 1.3±0.2 (=NH2+), pK1 = 3.88±0.02 (Alk-COOH), and pK2 = 5.28±0.02 (Ar-哦）。H2CEAnt 与铜 (II) 离子络合的模型涉及两个去质子化的络合物 [Cu(CEAnt)] 和 [Cu(CEAnt)2]2−（logβ = 6.31±0.04 和 8.0±0.2，分别）。[Cu(CEAnt)(H2O)]⋅H2O配合物是通过H2CEAnt与(CuOH)2CO3反应合成的，其结构通过X射线衍射确定。Cu的配位多面体介于四角锥和三角双锥之间。CEAnt2−
• Sensitized photopolymerizable compositions and use thereof in lithographic printing plates
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0730201A1

  公开（公告）日：1996-09-04

  Improved photopolymerization initiator systems are comprised of a spectral sensitizer that sensitizes in the ultraviolet or visible regions of the spectrum and an N-aryl, O-aryl or S-aryl polycarboxylic acid co-initiator. The improved initiator systems are incorporated in photo-polymerizable compositions containing one or more addition-polymerizable ethylenically-unsaturated compounds to form compositions suitable for the preparation of radiation-sensitive layers in lithographic printing plates adapted to be imagewise-exposed with ultraviolet- or visible-light-emitting lasers such as argon-ion lasers and frequency doubled Nd:YAG lasers. Such plates are able to effectively meet the dual requirements of very high photospeed and very good shelf-life required in computer-to-plate systems.

  改进的光聚合引发剂体系由在光谱的紫外线或可见光区域敏化的光谱敏化剂和 N-芳基、O-芳基或 S-芳基聚羧酸共引发剂组成。改进后的引发剂体系与含有一种或多种可加成聚合的乙烯基不饱和化合物的光聚合组合物结合，形成的组合物适用于制备平版印刷板中的辐射敏感层，该板可使用紫外线或可见光发射激光器（如氩离子激光器和倍频 Nd:YAG 激光器）进行图像曝光。这种印版能够有效地满足计算机直接制版系统对极高的光速和极好的保存期限的双重要求。
• Peel-developable lithographic printing plate
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0795790A2

  公开（公告）日：1997-09-17

  A peel-developable lithographic printing plate is comprised of a substrate, a hydrophilic layer comprising a polymeric acid overlying the substrate, a radiation-sensitive image-forming layer overlying the hydrophilic layer and a stripping layer that is strippably adhered to the image-forming layer. The image-forming layer is comprised of a photopolymerizable composition comprising a polymeric binder, a plurality of addition-polymerizable ethylenically-unsaturated compounds at least one of which possesses phosphorus-derived acidic functionality and a photopolymerization initiator. After imagewise exposure of the plate to activating radiation, the stripping layer is peeled from the image-forming layer with only the unexposed regions of the image-forming layer adhering thereto so as to reveal the underlying hydrophilic layer and thereby form a lithographic printing surface.

  一种可剥离显影平版印刷板由基底、覆盖在基底上的由聚合物酸组成的亲水层、覆盖在亲水层上的辐射敏感图像形成层和可剥离地粘附在图像形成层上的剥离层组成。图像形成层由可光聚合的组合物组成，该组合物包括聚合物粘合剂、多种可加成聚合的乙烯基不饱和化合物（其中至少一种具有磷衍生的酸性官能团）和光聚合引发剂。将印版按图像方向暴露在活化辐射下后，剥离层从图像形成层上剥离，只有图像形成层的未暴露区域附着其上，以显示底层亲水层，从而形成平版印刷表面。
• Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials
  申请人：Eigen Peter

  公开号：US20050148702A1

  公开（公告）日：2005-07-07

  Compositions comprising a mineral oil or wax and a liquid polysiloxane substituted by functional groups, an anionic surfactant and additionally a molecular mono- or polycarboxylic acid and optionally any emulsifiable, hydrophilic or amphiphilic polymer comprising carboxyl groups are outstanding water repellents for leather, furskins, textiles and fibrous materials.

  由矿物油或蜡和被官能团取代的液态聚硅氧烷、阴离子表面活性剂以及单羧酸或多羧酸分子和可选的包含羧基的任何可乳化的亲水或两性聚合物组成的复合物是皮革、毛皮、纺织品和纤维材料的出色防水剂。