4-chlorobutyryl peroxide | 21807-52-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-chlorobutyryl peroxide
• 英文别名: 4-Chlorobutanoyl 4-chlorobutaneperoxoate
• CAS: 21807-52-3
• 化学式: C₈H₁₂Cl₂O₄
• 分子量: 243.087
• InChiKey: KDVAENYRTAWMSW-UHFFFAOYSA-N

物化性质

• 沸点：
  310.7±52.0 °C(Predicted)
• 密度：
  1.277±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-chlorobutyryl peroxide 、 N-benzyl-N-(1-phenylvinyl)acetamide 在 tris(2,2′-bipyridyl)dichlororuthenium(II) hexahydrate 作用下， 以 1,2-二氯乙烷 为溶剂， 以88 %的产率得到(E)-N-benzyl-N-(6-chloro-1-phenylhex-1-en-1-yl)acetamide
  参考文献：
  名称：

  烯酰胺与二酰基过氧化物的光催化化学、区域和立体选择性烯属 β-C–H 脱羧烷基化

  摘要：

  描述了由可见光诱导的烯酰胺与烷基二酰基过氧化物的脱羧烷基化。化学、区域和立体选择性烯属 β-C–H 烷基化生成一系列伯烷基化和仲烷基化烯酰胺，产率高达 95%。该转化具有操作简单、官能团兼容性好、条件温和等优点。

  DOI：

  10.1039/d3cc01908j
• 作为产物：
  描述：

  4-氯丁酰氯 、 双氧水 以30%的产率得到
  参考文献：
  名称：

  CHAJKOVSKAYA V. A.; BOGUNETS N. P., BECTH. XARKOV. POLITEXN. IN-TA, 1980, HO 174, 62-65

  摘要：

  DOI：

文献信息

• Copper-catalyzed 1,4-alkylarylation of 1,3-enynes with masked alkyl electrophiles
  作者：Changqing Ye、Yajun Li、Xiaotao Zhu、Shengmin Hu、Daqiang Yuan、Hongli Bao

  DOI：10.1039/c8sc05689g

  日期：——

  A copper-catalyzed 1,4-alkylarylation of 1,3-enynes with alkyl diacyl peroxides as masked alkyl electrophiles and aryl boronic acids as nucleophiles, selectively affording structurally diversified tetrasubstituted allenes under mild conditions is reported.

  报道了一种铜催化的1,4-烷基芳基化反应，使用烷基双酰过氧化物作为掩蔽的烷基电泳性试剂和芳基硼酸作为亲核试剂，在温和条件下选择性地合成结构多样的四取代烯烃。
• Synthesis of 2-chloroalkyl-1,4-naphthoquinones and their reactivity in the formation of autocomplexes
  作者：Victor Prezhdo、Oleg Prezhdo、Elena Ovsiankina

  DOI：10.1016/0584-8539(95)01517-5

  日期：1995.12

  A series of the chloroalkyl derivatives of 1,4-naphtoquinone were synthesized and the electronic absorption spectra in 200-350 nm of these compounds were studied with the purpose of obtaining autocomplexes. The electronic absorption spectra of 1,4-naphtoquinones are characterized by four pi-pi* bands which have different sensitivity of lambda(max) to the electronic effects of the substituents. Some of the rules of the substituent influence on the spectral characteristics were found. Both steric factors, such as the formation of the cyclic structures due to the local interaction between the chloroethyl and chloropropyl radicals and the carbonyl of the quinone ring, and electronic effects, such as the insufficient delocalization of the extra change in -CH2-CH2+ leading to the poor stability of the carbocation, encumber the course of the reaction of complex formation.
• Prezhdo, V. V.; Bogunets, N. P.; Chaikovskaya, V. A., Journal of Organic Chemistry USSR (English Translation), 1987, vol. 23, # 7, p. 1366 - 1372
  作者：Prezhdo, V. V.、Bogunets, N. P.、Chaikovskaya, V. A.、Shevchenko, T. N.、Surov, Yu. N.

  DOI：——

  日期：——