1,3-dichloro-5-(3,3-dichloroallyloxy)-2-[3,3-dichloro-2-(4-trifluoromethylphenoxymethyl)-allyloxy]-benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-dichloro-5-(3,3-dichloroallyloxy)-2-[3,3-dichloro-2-(4-trifluoromethylphenoxymethyl)-allyloxy]-benzene
• 英文别名: 1,3-Dichloro-5-(3,3-dichloro-allyloxy)-2-[3,3-dichloro-2-(4-trifluoromethyl-phenoxymethyl)-allyloxy]-benzene；1,3-dichloro-5-(3,3-dichloroprop-2-enoxy)-2-[3,3-dichloro-2-[[4-(trifluoromethyl)phenoxy]methyl]prop-2-enoxy]benzene
• 化学式: C₂₀H₁₃Cl₆F₃O₃
• 分子量: 571.035
• InChiKey: IWANGICTTMJHHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  32
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  四氯化碳 、 1-[2,6-dichloro-4-(3,3-dichloroallyloxy)-phenoxy]-3-(4-trifluoromethylphenoxy)-propan-2-one 在 三苯基膦 作用下， 以 乙腈 为溶剂， 反应 24.0h， 生成 1,3-dichloro-5-(3,3-dichloroallyloxy)-2-[3,3-dichloro-2-(4-trifluoromethylphenoxymethyl)-allyloxy]-benzene
  参考文献：
  名称：

  [EN] PESTICIDALLY ACTIVE PHENOL DERIVATIVES
  [FR] DERIVES PHENOLIQUES A ACTIVITE PESTICIDE

  摘要：

  公开号：

  WO2005019147A3

文献信息

• Pesticidally active phenol derivatives
  申请人：Zambach Werner

  公开号：US20070142229A1

  公开（公告）日：2007-06-21

  There are described compounds of formula (I) wherein X 1 and X 2 are each independently of the other fluorine, chlorine or bromine; A 1 and A 2 are, for example, a bond or a C 1 -C 6 alkylene bridge; A 3 is a C 1 -C 6 alkylene bridge; R 1 and R 2 are, for example halogen, OH, SH, CN, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl-carbonyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl or C 3 -C 6 alkynyl; R, 3 is, for example, H, halogen, OH, SH, CN, nitro, C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; R 4 and R 5 are, for example, H, halogen, cyano, nitro, C 1 -C 6 alkyl or C 1 -C 3 haloalkyl; m is 1 or 2; Y is, for example, O, S, SO or SO 2 ; Q is, for example, O, S, SO or SO 2 ; W is, for example, a bond, O, S, SO, S02, —C(═O)—O— or —O—C(═O)—; T is, for example, a bond, O, S, SO, SO 2 , —C(═O)—O— or —O—C(═O)—; and E is aryl unsubstituted or substituted from one to five times or heterocyclyl unsubstituted or, depending upon the possibilities of substitution on the ring, substituted from one to four times; and, where applicable, their possible E/Z isomers, E/Z isomeric mixtures and/or tautomers, in each case in free form or in salt form, a process for the preparation of those compounds and their use, pesticidal compositions in which the active ingredient has been selected from those compounds and agrochemically acceptable salts thereof, a process for the preparation of those compositions and their use, plant propagation material treated with those compositions, and a method of controlling pests.

  描述了化合物的公式(I)，其中X1和X2各自独立地是氟、氯或溴；A1和A2是例如键或C1-C6烷基桥；A3是C1-C6烷基桥；R1和R2是例如卤素、OH、SH、CN、硝基、C1-C6烷基、C1-C6卤代烷基、C1-C6烷基-羰基、C2-C6烯基、C2-C6卤代烯基或C3-C6炔基；R3是例如H、卤素、OH、SH、CN、硝基、C1-C6烷基或C1-C6卤代烷基；R4和R5是例如H、卤素、氰基、硝基、C1-C6烷基或C1-C3卤代烷基；m为1或2；Y是例如O、S、SO或SO2；Q是例如O、S、SO或SO2；W是例如键、O、S、SO、SO2、-C(═O)-O-或-O-C(═O)-；T是例如键、O、S、SO、SO2、-C(═O)-O-或-O-C(═O)-；E是芳基未取代或取代一至五次或杂环芳基未取代或根据环上的取代可能性，取代一至四次；以及可能的E/Z异构体、E/Z异构体混合物和/或互变异构体，每种情况均为自由形式或盐形式，制备这些化合物的过程及其用途，所述活性成分选自这些化合物和其农药组合物，制备这些组合物的过程及其用途，用这些组合物处理的植物繁殖材料以及控制害虫的方法。
• ANTI-HISTAMINE COMPOSITIONS AND USE THEREOF
  申请人：Taro Pharmaceuticals U.S.A., Inc.

  公开号：EP2029132A2

  公开（公告）日：2009-03-04
• US7638514B2
  申请人：——

  公开号：US7638514B2

  公开（公告）日：2009-12-29
• [EN] ANTI-HISTAMINE COMPOSITIONS AND USE THEREOF<br/>[FR] COMPOSITIONS ANTIHISTAMINIQUES ET LEUR UTILISATION
  申请人：TARO PHARMACEUTICALS USA INC

  公开号：WO2007087344A2

  公开（公告）日：2007-08-02

  [EN] The present invention provides for a storage stable pharmaceutical liquid solution for oral administration having a pharmaceutically effective amount of an antihistamine and having a purity equal to or greater than about 99% by weight-based HPLC assay, residual solvents of less than about 0.5%, and a total impurity of less than about 0.2%. The storage stable solution preferably contains cetirizine. The present invention further provides a process of preparing the storage stable pharmaceutical liquid solution as well as a method of treating a mammal with a therapeutically effective amount of cetirizine in the stable pharmaceutical liquid solution.
  [FR] La présente invention concerne une solution liquide pharmaceutique stable au stockage destinée à être administrée par voie orale renfermant une quantité pharmaceutiquement efficace d'un antihistaminique et présentant une pureté égale ou supérieure à environ 99 % par dosage HPLC fondé sur le poids, une quantité de solvants résiduels inférieure à environ 0,5 % et une quantité totale d'impuretés inférieure à environ 0,2 %. La solution stable au stockage contient de préférence de la cétirizine. Cette invention concerne également un procédé de préparation de la solution liquide pharmaceutique stable au stockage ainsi qu'une méthode de traitement d'un mammifère faisant appel à une quantité thérapeutiquement efficace de cétirizine dans la solution liquide pharmaceutique stable.
• [EN] PESTICIDALLY ACTIVE PHENOL DERIVATIVES<br/>[FR] DERIVES PHENOLIQUES A ACTIVITE PESTICIDE
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2005019147A3

  公开（公告）日：2005-04-07