5,7,3',4'-tetra-hydroxyethyl rutoside | 31511-31-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 5,7,3',4'-tetra-hydroxyethyl rutoside
• 英文别名: tetrahydroxyethylrutoside；5,7,3',4'-tetrahydroxyethylrutoside；Tetra-O-(beta-hydroxyethyl)rutoside；2-[3,4-bis(2-hydroxyethoxy)phenyl]-5,7-bis(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
• CAS: 31511-31-6
• 化学式: C₃₅H₄₆O₂₀
• 分子量: 786.738
• InChiKey: OHHXJHPHUFVCPR-XQZWLAGVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  55
• 可旋转键数：
  18
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  302
• 氢给体数：
  10
• 氢受体数：
  20

反应信息

• 作为产物：
  描述：

  rutin 、 环氧乙烷 生成 5,7,3',4'-tetra-hydroxyethyl rutoside
  参考文献：
  名称：

  STEFANOV, ZH. S.;DREBOVA, N. S.;JORDANOVA, G. I.;IVANOV, A. P.;STRASHILOV+

  摘要：

  DOI：

文献信息

• Troxerutin with a high content of trihydroxyethylrutoside and process for its preparation
  申请人：Estanove Cyril

  公开号：US06855697B1

  公开（公告）日：2005-02-15

  The invention concerns novel troxerutin with high trihydroxy-ethyl-rutin content. Said troxerutin has at least 92 wt. % of 7,3′,4′-trihydroxyethyl rutin and a wettability expressed in minutes less than 10 minutes, when said wettability is measured in a test consisting in measuring the time taken by 3.5 g of said enriched troxerutin powder to leave the surface of a beaker containing 100 ml of water, at a stabilised temperature of 20° C., when said enriched troxerutin powder is poured at the surface of the water in said beaker, and a wettability less than 100 seconds when said wettability is measured in a test consisting in measuring the time taken by said enriched troxerutin to be wetted by the water contained in a receptacle, such as a beaker, when said enriched troxerutin has been deposited at the surface of the water, in the form of cores of 2 mm wide and 3 mm high weighing 63 ? 2 mg, at a stabilised temperature of 20° C. Said troxerutin has improved properties of wettability and solubility in water.

  本发明涉及一种具有高三羟乙基芦丁含量的新型曲沙酮。所述曲沙酮至少含有92重量％的7,3′,4′-三羟乙基芦丁，当通过测量富集曲沙酮粉末倒在100毫升水的烧杯表面后，3.5克富集曲沙酮粉末离开烧杯表面所需的时间，以及当通过测量富集曲沙酮在20℃的稳定温度下以2毫米宽、3毫米高的核心形式放置在水表面时，富集曲沙酮被水润湿所需的时间小于100秒时，具有改善的润湿性和溶解性能。
• 一种羟乙基芦丁的制备方法
  申请人：李玉山

  公开号：CN115403636A

  公开（公告）日：2022-11-29

  本发明利用芦丁的4个酚羟基酸性不同，在不同碱性环境下，与不同的金属离子在不同的酚羟基处生成络合物，从而在Williamson合成中该位置处不会产生羟乙基化，羟乙基化结束后，脱除金属离子，达到生成目标化合物。据本发明的方法，合成了莫诺芦丁、二羟乙基芦丁、曲克芦丁、四羟乙基芦丁和羟乙基芦丁高聚合物。
• STEFANOV, ZH. S.;DREBOVA, N. S.;JORDANOVA, G. I.;IVANOV, A. P.;STRASHILOV+
  作者：STEFANOV, ZH. S.、DREBOVA, N. S.、JORDANOVA, G. I.、IVANOV, A. P.、STRASHILOV+

  DOI：——

  日期：——