3-((3,4-difluorophenyl)carbamoyl)-4-fluorobenzene-1-sulfonyl chloride | 1616809-39-2

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

3-((3,4-difluorophenyl)carbamoyl)-4-fluorobenzene-1-sulfonyl chloride

英文别名

3-(3,4-Difluorophenylcarbamoyl)-4-fluorobenzene-1-sulfonyl chloride；3-[(3,4-difluorophenyl)carbamoyl]-4-fluorobenzenesulfonyl chloride

3-((3,4-difluorophenyl)carbamoyl)-4-fluorobenzene-1-sulfonyl chloride化学式

CAS

1616809-39-2

化学式

C₁₃H₇ClF₃NO₃S

mdl

——

分子量

349.718

InChiKey

HBOVWCQCPCPGJZ-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

沸点：

388.3±42.0 °C(Predicted)
密度：

1.607±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

辛醇/水分配系数(LogP)：

3.1
重原子数：

22
可旋转键数：

3
环数：

2.0
sp3杂化的碳原子比例：

0.0
拓扑面积：

71.6
氢给体数：

1
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	5-(chlorosulfonyl)-2-fluorobenzoyl chloride	949485-81-8	C₇H₃Cl₂FO₃S	257.069
5-(氯磺酰基)-2-氟苯甲酸	5-(chlorosulfonyl)-2-fluorobenzoic acid	37098-75-2	C₇H₄ClFO₄S	238.624

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	N-(3,4-difluorophenyl)-2-fluoro-5-sulfamoylbenzamide	1616809-21-2	C₁₃H₉F₃N₂O₃S	330.287
——	N-(3,4-difluorophenyl)-5-(N-ethoxysulfamoyl)-2-fluorobenzamide	1616808-03-7	C₁₅H₁₃F₃N₂O₄S	374.34
——	N-(3,4-difluorophenyl)-5-(N-(2-(dimethylamino)ethyl)sulfamoyl)-2-fluorobenzamide	1616807-93-2	C₁₇H₁₈F₃N₃O₃S	401.409
——	isopropyl 3-((3,4-difluorophenyl)carbamoyl)-4-fluorobenzenesulfonate	1616809-23-4	C₁₆H₁₄F₃NO₄S	373.353
——	(S)-N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-hydroxypropan-2-yl)sulfamoyl)benzamide	1616807-59-0	C₁₆H₁₅F₃N₂O₄S	388.367
——	(R)-N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-hydroxypropan-2-yl)sulfamoyl)benzamide	1616807-60-3	C₁₆H₁₅F₃N₂O₄S	388.367
——	5-(N-cyclopropylsulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616808-32-2	C₁₆H₁₃F₃N₂O₃S	370.352
——	N-(3,4-difluorophenyl)-5-(N-(dimethylcarbamoyl)sulfamoyl)-2-fluorobenzamide	1616809-22-3	C₁₆H₁₄F₃N₃O₄S	401.366
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(methylsulfonyl)sulfamoyl)benzamide	1616809-26-7	C₁₄H₁₁F₃N₂O₅S₂	408.379
——	N-(3,4-difluorophenyl)-5-(N-(N,N-dimethylcarbamimidoyl)sulfamoyl)-2-fluorobenzamide	1616809-25-6	C₁₆H₁₅F₃N₄O₃S	400.381
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-tert-pentylsulfamoyl)benzamide	1616807-58-9	C₁₈H₁₉F₃N₂O₃S	400.422
——	5-(N-(cyclopentylmethyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616807-88-5	C₁₉H₁₉F₃N₂O₃S	412.433
——	5-(N-cyclopentylsulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	422547-70-4	C₁₈H₁₇F₃N₂O₃S	398.406
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(3-methyloxetan-3-yl)sulfamoyl)benzamide	1616807-97-6	C₁₇H₁₅F₃N₂O₄S	400.378
——	(R)-5-(N-(1-cyclopropylethyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616807-78-3	C₁₈H₁₇F₃N₂O₃S	398.406
——	N-(3,4-difluorophenyl)-5-(N-(1-ethylcyclopropyl)sulfamoyl)-2-fluorobenzamide	1616807-77-2	C₁₈H₁₇F₃N₂O₃S	398.406
——	(S)-2-(3-((3,4-difluorophenyl)carbamoyl)-4-fluorophenylsulfonamido)propanoic acid	1616809-05-2	C₁₆H₁₃F₃N₂O₅S	402.351
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-imino-2-methylpropyl)sulfamoyl)benzamide	1616809-24-5	C₁₇H₁₆F₃N₃O₃S	399.394
——	5-(N-(cyclopropanecarbonyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616809-20-1	C₁₇H₁₃F₃N₂O₄S	398.362
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-morpholinosulfamoyl)benzamide	1616808-04-8	C₁₇H₁₆F₃N₃O₄S	415.393
——	(R)-5-(N-(1-cyclohexylethyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616807-81-8	C₂₁H₂₃F₃N₂O₃S	440.486
——	5-((3,3-difluoroazetidin-1-yl)sulfonyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	——	C₁₆H₁₁F₅N₂O₃S	406.333
——	5-(N-(1-adamantyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616807-90-9	C₂₃H₂₃F₃N₂O₃S	464.508
——	(R)-N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(tetrahydro-2H-pyran-4-yl)ethyl)sulfamoyl)benzamide	1616807-92-1	C₂₀H₂₁F₃N₂O₄S	442.459
——	(R)-N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(pyridin-4-yl)ethyl)sulfamoyl)benzamide	1616808-00-4	C₂₀H₁₆F₃N₃O₃S	435.427
——	(S)-N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1,1,1-trifluoro-3-methylbutan-2-yl)sulfamoyl)benzamide	1616808-06-0	C₁₈H₁₆F₆N₂O₃S	454.393
——	5-(N-(2-adamantyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616807-89-6	C₂₃H₂₃F₃N₂O₃S	464.508
——	isopropyl ((3-((3,4-difluorophenyl)carbamoyl)-4-fluorophenyl)sulfonyl)-l-alaninate	——	C₁₉H₁₉F₃N₂O₅S	444.431
——	N-(3,4-difluorophenyl)-5-((4,4-difluoropiperidin-1-yl)sulfonyl)-2-fluorobenzamide	——	C₁₈H₁₅F₅N₂O₃S	434.387
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(pyrimidin-2-yl)ethyl)sulfamoyl)benzamide	1616807-98-7	C₁₉H₁₅F₃N₄O₃S	436.414
——	5-(N-(1-cyclohexylcyclopropyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616807-91-0	C₂₂H₂₃F₃N₂O₃S	452.497
——	(S)-5-(N-(1-cyclopropyl-2,2,2-trifluoroethyl)sulfamoyl)-N-(3,4-difluorophenyl)-2-fluorobenzamide	1616808-07-1	C₁₈H₁₄F₆N₂O₃S	452.377
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(trifluoromethyl)cyclobutyl)sulfamoyl)benzamide	1616839-21-4	C₁₈H₁₄F₆N₂O₃S	452.377
——	(R)-N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(pyridin-3-yl)ethyl)sulfamoyl)benzamide	——	C₂₀H₁₆F₃N₃O₃S	435.427
——	N-(3,4-difluorophenyl)-5-((3,3-difluoropyrrolidin-1-yl)sulfonyl)-2-fluorobenzamide	——	C₁₇H₁₃F₅N₂O₃S	420.36
——	ethyl ((3-((3,4-difluorophenyl)carbamoyl)-4-fluorophenyl)sulfonyl)-l-leucinate	——	C₂₁H₂₃F₃N₂O₅S	472.485
——	N-(3,4-difluorophenyl)-2-fluoro-5-((3,3,4,4-tetrafluoropyrrolidin-1-yl)sulfonyl)benzamide	——	C₁₇H₁₁F₇N₂O₃S	456.341
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(pyridin-2-yl)ethyl)sulfamoyl)benzamide	1616807-99-8	C₂₀H₁₆F₃N₃O₃S	435.427
——	N-(3,4-difluorophenyl)-2-fluoro-5-(N-(1-(pyridin-4-yl)cyclopropyl)sulfamoyl)benzamide	1616808-02-6	C₂₁H₁₆F₃N₃O₃S	447.438

3-((3,4-difluorophenyl)carbamoyl)-4-fluorobenzene-1-sulfonyl chloride | 1616809-39-2

分子结构分类

物化性质

计算性质

上下游信息

反应信息