N,N-di(2-ethylhexyl)acetamide-2-glycine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N-di(2-ethylhexyl)acetamide-2-glycine
• 英文别名: N-[N,N-bis(2-ethylhexyl)aminocarbonylmethyl]glycine；N-[N,N-di(2-ethylhexyl) aminocarbonylmethyl] glycine；N-[N,N-di(2-ethylhexyl)aminocarbonylmethyl]-glycine；2-[[2-[bis(2-ethylhexyl)amino]-2-oxoethyl]amino]acetic acid
• 化学式: C₂₀H₄₀N₂O₃
• 分子量: 356.549
• InChiKey: HMFCNOSAXCXHGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  25
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  69.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  methyltrioctylammonium hydroxide 、 N,N-di(2-ethylhexyl)acetamide-2-glycine 以 二氯甲烷 为溶剂， 以93 %的产率得到
  参考文献：
  名称：

  [A336][DGA]型离子液体在酸性体系下萃取分离制备核级锆、核级铪的方法

  摘要：

  本发明采用了[A336][DGA]型离子液体对锆铪的萃取结果为：在无机酸浓度为0.5～6mol/L时，锆铪萃取效率相差50～70％，分离系数βZr/Hf达到10～20，[A336][DGA]‑HCl系统最佳的萃取酸度范围实现Zr、Hf的高效萃取。本发明采用的[A336][DGA]‑无机酸萃取体系，在相应的酸度范围内，单级分离系数可达10～20，锆铪很容易被完全分离。因此具有工艺流程简单，萃取分离系数大，通过分馏萃取分离可获的锆和铪两个核级产品，产品质量稳定可靠。

  公开号：

  CN115504901A
• 作为产物：
  描述：

  二异辛胺 在 三乙胺 、 sodium hydroxide 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 18.0h， 生成 N,N-di(2-ethylhexyl)acetamide-2-glycine
  参考文献：
  名称：

  使用有前途的氨基甲酸萃取剂系统对 99TcO4–/ReO4– 进行超选择性萃取再处理

  摘要：

  随着核能的发展，99 TcO 4 - /ReO 4 -的后处理由于产量高、寿命长、易泄漏等环保问题成为一个非常棘手的问题。本研究首次将三种含有氨基甲酸的萃取系统引入到99 TcO 4 – /ReO 4 –的后处理中。涉及三个结果之一的结果表明，N -[ N , N -di(2-ethylhexyl) aminocarbonylmethyl] glycine (D2EHAG) has ultrahigh selectivity for removal to 99 TcO 4 –/ReO 4 –。当D2EHAG的SO 4 2-和Cl -与ReO 4 -的极限浓度比为10000:1时，ReO 4 -的分配系数仍分别达到12.73和2.67。此外，最亲水的 NO 3 - ，当 NO 3 -和 ReO 4 -的极端浓度比时为 1000:1，仍具有接近 2.33 的分配系数，超过了大多数报道的 MOF

  DOI：

  10.1021/acs.inorgchem.2c03708

文献信息

• SCANDIUM EXTRACTION METHOD
  申请人：Kyushu University, National University Corporation

  公开号：US20140377150A1

  公开（公告）日：2014-12-25

  Provided is a method for selectively extracting and inexpensively recovering scandium from an acidic solution containing calcium, magnesium, and scandium. The scandium extraction method according to the present invention involves subjecting an acidic solution containing calcium, magnesium, and scandium to solvent extraction using an extraction agent consisting of an amide derivative represented by the general formula below. In the formula, R 1 and R 2 represent the same or different alkyl groups, and R 3 is a hydrogen atom or alkyl group. The amide derivative preferably consisting of one or more derivatives selected from glycine amide derivatives, histidine amide derivatives, lysine amide derivatives, and aspartic acid amide derivatives. The pH of the acidic solution is preferably pre-adjusted to between 1 and 4.

  提供了一种从含有钙、镁和钪的酸性溶液中选择性地提取和廉价地回收钪的方法。根据本发明的钪提取方法涉及将含有钙、镁和钪的酸性溶液暴露于使用由下面的一般公式表示的酰胺衍生物组成的萃取剂的溶剂萃取中。在该公式中，R1和R2代表相同或不同的烷基基团，R3是氢原子或烷基基团。该酰胺衍生物最好由从甘氨酰胺衍生物、组氨酰胺衍生物、赖氨酰胺衍生物和天冬氨酸酰胺衍生物中选择的一个或多个衍生物组成。酸性溶液的pH最好预先调整到1至4之间。
• Selective extraction of scandium from yttrium and lanthanides with amic acid-type extractant containing alkylamide and glycine moieties
  作者：Yuzo Baba、Arisa Fukami、Fukiko Kubota、Noriho Kamiya、Masahiro Goto

  DOI：10.1039/c4ra08897b

  日期：——

  earth metal ions (scandium (Sc3+), yttrium (Y3+) and the lanthanides (La3+, Nd3+, Eu3+ and Dy3+)) was investigated using N-[N,N-di(2-ethylhexyl)aminocarbonylmethyl]glycine (D2EHAG). Scandium was extracted selectively from lanthanides under highly acidic conditions (0 < pH ≤ 1.5), and stripped easily using a mild acidic solution such as 1 mol dm−3 H2SO4. By comparing the extraction behavior with N,N-dioctyldiglycol

  稀土金属离子的液-液萃取（钪（Sc 3+），钇（Y 3+）和镧系元素（LA 3+，钕3+，Eu的3+和Dy 3+使用））进行了研究ñ - [ N，N-二（2-乙基己基）氨基羰基甲基]甘氨酸（D2EHAG）。在高酸性条件下（0
• ZIRCONIUM EXTRACTANT AND METHOD FOR EXTRACTING ZIRCONIUM
  申请人：Kyushu University, National University Corporation

  公开号：US20180010211A1

  公开（公告）日：2018-01-11

  Provided are: an extractant which is capable of quickly and highly efficiently extracting zirconium from an acidic solution that is obtained by acid leaching a material containing zirconium and scandium such as an SOFC electrode material; and a method for extracting zirconium, which uses this extractant. A zirconium extractant according to the present invention is composed of an amide derivative represented by general formula (I). In the formula, R1 and R2 respectively represent the same or different alkyl groups, each of which may be linear or branched; R3 represents a hydrogen atom or an alkyl group; and R4 represents a hydrogen atom or an arbitrary group other than an amino group, said arbitrary group being bonded, as an amino acid, to the α carbon.

  提供了一种萃取剂，能够快速高效地从通过酸浸提取含锆和钪材料（如SOFC电极材料）得到的酸性溶液中提取锆；以及使用该萃取剂的提取锆的方法。根据本发明的锆萃取剂由一般式（I）表示的酰胺衍生物组成。在该式中，R1和R2分别表示相同或不同的烷基基团，每个基团可以是直链或支链；R3表示氢原子或烷基基团；R4表示氢原子或除氨基以外的任意基团，该任意基团作为氨基酸与α碳结合。
• COBALT EXTRACTION METHOD
  申请人：Kyushu University, National University Corporation

  公开号：EP2682486A1

  公开（公告）日：2014-01-08

  The objective of the present invention is to selectively extract cobalt from an acidic solution containing a high concentration of manganese. This cobalt extraction method extracts cobalt from an acidic solution containing manganese and cobalt by subjecting the acidic solution to solvent extraction by means of a valuable metal extraction agent comprising an amide derivative represented by general formula (I). The valuable metal extraction agent is represented by the general formula. In the formula: R1 and R2 each represent the same or different alkyl group; R3 represents a hydrogen atom or an alkyl group; and R4 represents a hydrogen atom or any given group aside from an amino group bonded to the a carbon as an amino acid. Preferably, the general formula has a glycine unit, a histidine unit, a lysine unit, an aspartic acid unit, or an N-methylglycine unit. Preferably, the pH of the acidic solution is 3.5-5.5 inclusive.

  本发明的目的是从含有高浓度锰的酸性溶液中选择性地提取钴。本发明的钴萃取方法是从含有锰和钴的酸性溶液中萃取钴，其方法是将酸性溶液用溶剂萃取，溶剂萃取剂包括通式(I)表示的酰胺衍生物。有价金属萃取剂由通式表示。式中R1 和 R2 分别代表相同或不同的烷基；R3 代表氢原子或烷基；R4 代表氢原子或除作为氨基酸键合在碳上的氨基外的任何基团。通式中最好有一个甘氨酸单元、一个组氨酸单元、一个赖氨酸单元、一个天冬氨酸单元或一个 N-甲基甘氨酸单元。酸性溶液的 pH 值最好在 3.5-5.5 之间。
• NICKEL EXTRACTION METHOD
  申请人：Kyushu University, National University Corporation

  公开号：EP2902511A1

  公开（公告）日：2015-08-05

  In the present invention, nickel is selectively extracted from an acidic solution that contains a high concentration of manganese. This valuable metal extraction agent is represented by the general formula. In the formula, R1 and R2 are alkyl groups that may be the same or different, R3 is a hydrogen atom or an alkyl group, and R4 is a hydrogen atom or any group, other than an amino group, bonded to an α carbon atom of an amino acid. The general formula preferably has a glycine unit, a histidine unit, a lysine unit, an aspartic acid unit or a n-methylglycine unit. When extracting nickel by using this extraction agent, it is preferable to adjust the pH of the acidic solution to 2.3 to 5.5 inclusive.

  在本发明中，镍被选择性地从含有高浓度锰的酸性溶液中提取出来。这种有价金属萃取剂由通式表示。式中，R1 和 R2 是可以相同或不同的烷基，R3 是氢原子或烷基，R4 是氢原子或与氨基酸的 α 碳原子键合的任何基团（氨基除外）。通式中最好有一个甘氨酸单元、一个组氨酸单元、一个赖氨酸单元、一个天冬氨酸单元或一个正甲基甘氨酸单元。使用这种萃取剂萃取镍时，最好将酸性溶液的 pH 值调至 2.3 至 5.5（含 5.5）。