1-烯丙基-2-乙氧基苯 | 3698-31-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 1-烯丙基-2-乙氧基苯
• 英文名称: 2-allyl-phenetole
• 英文别名: 2-Allyl-phenetol；2-Aethoxy-1-allyl-benzol；Aethyl-(2-allyl-phenyl)-aether；3-(2-Ethoxyphenyl)-1-propene；1-ethoxy-2-prop-2-enylbenzene
• CAS: 3698-31-5
• 化学式: C₁₁H₁₄O
• 分子量: 162.232
• InChiKey: PWELCSAEYLPLQB-UHFFFAOYSA-N

物化性质

• 沸点：
  101-103 °C(Press: 20 Torr)
• 密度：
  0.930±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909309090

反应信息

• 作为反应物：
  描述：

  1-烯丙基-2-乙氧基苯 在 dihydrogen hexachloroplatinate 溴化乙啶 、 magnesium 作用下， 以 四氢呋喃 、 异丙醇 为溶剂， 生成 3-(2-ethoxyphenyl)propyl-ethynyl-dimethylsilane
  参考文献：
  名称：

  2- and 3-arylpropyl(ethynyl)dimethylsilanes

  摘要：

  对邻位和对位取代的2-苯丙烯以及邻位、间位和对位醇基取代的3-苯丙烯，与氯二甲基硅烷在H2PtCl6的催化下进行水硅化反应。所得加成产物与乙炔镁溴化物反应，合成了2-和3-芳基丙基(乙炔)硅烷。

  DOI：

  10.1007/s11176-005-0113-5
• 作为产物：
  描述：

  溴乙烷 、 2-烯丙基酚 在 乙醇 、 sodium ethanolate 作用下， 生成 1-烯丙基-2-乙氧基苯
  参考文献：
  名称：

  Schamschurin; Ibadulin, Zhurnal Obshchei Khimii, 1949, vol. 19, p. 1669,1672

  摘要：

  DOI：

文献信息

• Transition Metal Free Intermolecular Direct Oxidative C–N Bond Formation to Polysubstituted Pyrimidines Using Molecular Oxygen as the Sole Oxidant
  作者：Wei Guo、Chunsheng Li、Jianhua Liao、Fanghua Ji、Dongqing Liu、Wanqing Wu、Huanfeng Jiang

  DOI：10.1021/acs.joc.6b00867

  日期：2016.7.1

  polysubstituted pyrimidines are smoothly formed via a base-promoted intermolecular oxidation C–N bond formation of allylic C(sp3)–H and vinylic C(sp2)–H of allyllic compounds with amidines using O2 as the sole oxidant. This protocol features protecting group free nitrogen sources, good functional group tolerance, high atom economy, and environmental advantages.

  各种多取代的嘧啶通过烯丙基化合物的烯丙基C（sp 3）-H和烯丙基C（sp 2）-H与am的碱促进的分子间氧化C-N键形成，使用O 2作为唯一氧化剂，可顺利形成。该协议具有保护基自由氮源，良好的官能团耐受性，高原子经济性和环境优势的特点。
• A Visible Light and Iron‐mediated Carbocationic Route to Polysubstituted 1‐Halonaphthalenes by Benzannulation using Allylbenzenes and Polyhalomethanes
  作者：Irwan Iskandar Roslan、Hongwei Zhang、Kian‐Hong Ng、Stephan Jaenicke、Gaik‐Khuan Chuah

  DOI：10.1002/adsc.202001249

  日期：2021.2.16

  A wide array of polysubstituted 1‐bromo and chloronaphthalenes are obtained from coupling of allylbenzenes and polyhalomethanes. The reaction is mediated by iron metal under visible light irradiation and proceeds via a Kharasch addition intermediate followed by intramolecular FeIII mediated Friedel‐Crafts alkylation, with the formation of two Csp2−Csp2 bonds in the process. This method gives easy access

  烯丙基苯与多卤代甲烷的偶联可得到各种各样的多取代的1-溴和氯萘。该反应在可见光辐射下由铁金属介导，并通过Kharasch加成中间体进行，然后进行分子内Fe III介导的Friedel-Crafts烷基化，在此过程中形成两个C sp 2 -C sp 2键。该方法可轻松获得具有C-5至C-8取代基的1-卤代萘，否则难以合成。
• Hair Processing Agent And Method For Permanent Waving Hair
  申请人：Shibuya Akira

  公开号：US20080085251A1

  公开（公告）日：2008-04-10

  Provided are hair processing agents capable of permanent waving hair even at a neutral to weakly acidic pH range that causes less irritation to the skin, and hair processing agents in which an unpleasant odor is masked. Hair processing agents contain at least one compound represented by the formula (2). Hair processing agents contain a compound of the formula (2) and at least one compound (ii) selected from thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine, salts thereof and ester derivatives thereof. Hair processing agents contain a compound of the formula (2), a surfactant and water, and are emulsified. Hair processing agents contain a compound of the formula (2) and a specific perfume. wherein X is a structure selected from —O—, —S—, —NH— and —NR 1 —; R 1 is an alkyl group of 1 to 6 carbon atoms; Y is an oxygen atom or a sulfur atom; in the formula (1), Z is a divalent organic residue having at least one mercapto group; in the formula (2), R is a divalent organic residue optionally having a mercapto group; and R 2 is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms.

  提供了能够在中性至微酸性pH范围内进行永久性卷发的头发处理剂，其对皮肤刺激较小，并且掩盖了不愉快的气味。头发处理剂包含至少一种由公式（2）表示的化合物。头发处理剂包含公式（2）的化合物和至少一种从巯基乙酸，巯基乳酸，半胱氨酸，乙酰半胱氨酸，半胱氨醇，酰基半胱氨醇，其盐和酯衍生物中选择的化合物（ii）。头发处理剂包含公式（2）的化合物，表面活性剂和水，并且是乳化的。头发处理剂包含公式（2）的化合物和特定香水。其中X是从-O-，-S-，-NH-和-NR1-选择的结构；R1是1到6个碳原子的烷基；Y是氧原子或硫原子；在公式（1）中，Z是具有至少一个巯基的二价有机残基；在公式（2）中，R是二价的有机残基，可选地具有巯基；R2是氢原子或1到6个碳原子的烷基。
• Method for oxidizing unsaturated aromatic compounds
  申请人：NIPPON PETROCHEMICALS COMPANY, LIMITED

  公开号：EP0350069A2

  公开（公告）日：1990-01-10

  This invention relates to a method for manufacturing aromatic compounds having the following formula (II) comprising the step of reacting an unsaturated aromatic compound having the following formula (I) with an aryl compound containing an iodosyl group or the salt thereof within a temperature range of from -50 to 200oC:

  本发明涉及一种制造具有下式（II）的芳香族化合物的方法，该方法包括以下步骤：将具有下式（I）的不饱和芳香族化合物与含有碘代基团的芳基化合物或其盐在-50 至 200 摄氏度的温度范围内进行反应：
• Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP0637580A1

  公开（公告）日：1995-02-08

  A 1-bromoalkylbenzene derivative is prepared by reacting a phenylalkene derivative with hydrogen bromide in the presence of a non-polar solvent. The phenylalkene derivative is prepared by reacting an alkenyl halide with metal magnesium to form a Grignard reagent, and then reacting the Grignard reagent with a benzyl halide derivative. An allyl Grignard reagent is prepared by reacting continuously an allyl halide derivative with metal magnesium in an organic solvent, in which the allyl halide derivative and metal magnesium are continuously added to the reaction system and the allyl Grignard reagent formed is continuously removed from the reaction system. The processes provide the intended compounds in high yields, high selectivities and high purities.

  1-bromoalkylbenzene derivative is prepared by reacting a phenylalkene derivative with hydrogen bromide in the presence of a non-polar solvent.苯基烷烃衍生物的制备方法是先使烯基卤化物与金属镁反应生成格氏试剂，然后使格氏试剂与苄基卤化物衍生物反应。烯丙基格氏试剂是通过烯丙基卤化物衍生物与金属镁在有机溶剂中连续反应制备的，其中烯丙基卤化物衍生物和金属镁被连续加入反应体系，形成的烯丙基格氏试剂被连续从反应体系中移除。这些工艺可提供高产率、高选择性和高纯度的预期化合物。