5,5́-thio-bis(salicylaldehyde) | 157693-28-2

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 5,5́-thio-bis(salicylaldehyde)
• 英文别名: bis(3-formyl-4-hydroxyphenyl) sulfide；di(3-formyl-4-hydroxyphenyl) sulfide；5-(3-formyl-4-hydroxyphenyl)sulfanyl-2-hydroxybenzaldehyde
• CAS: 157693-28-2
• 化学式: C₁₄H₁₀O₄S
• 分子量: 274.297
• InChiKey: AIXAAQZXSBILOH-UHFFFAOYSA-N

物化性质

• 沸点：
  492.5±45.0 °C(Predicted)
• 密度：
  1.48±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  99.9
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  叔丁胺 、 5,5́-thio-bis(salicylaldehyde) 以 氯仿 为溶剂， 反应 0.5h， 以75%的产率得到2-(Tert-butyliminomethyl)-4-[3-(tert-butyliminomethyl)-4-hydroxyphenyl]sulfanylphenol
  参考文献：
  名称：

  Allakhverdiev; Babai; Farzaliev, Petroleum Chemistry, 2001, vol. 41, # 2, p. 135 - 139

  摘要：

  DOI：
• 作为产物：
  描述：

  水杨醛 在 二氯化硫 、 锌 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以76%的产率得到5,5́-thio-bis(salicylaldehyde)
  参考文献：
  名称：

  Golodnyuk, T.I.; Vinogradova, V.I., Russian Journal of Organic Chemistry, 1993, vol. 29, # 9, p. 1593

  摘要：

  DOI：

文献信息

• Structural analysis of diorganotin(IV) complexes derived from thio bis-tridentate Schiff base ligands
  作者：Arturo González-Hernández、Víctor Barba

  DOI：10.1016/j.ica.2018.08.026

  日期：2018.11

  Twelve dinuclear diorganotin(IV) complexes based on bis-tridentate Schiff bases and R2SnO (IV) oxides (R = Me, n-Bu, Ph) were synthesized by multicomponent reactions in moderate yields. The complexes were characterized by common spectroscopic techniques such as FT-IR, mass spectrometry and NMR (H-1, C-13 and Sn-119) analysis. X-ray diffraction analysis was done for compounds 1c, 1d, 1f, 1j and 1l. Sn-119 NMR spectra showed signals at delta = 135-145, 175-185 and 319-323 ppm for Me, n-Bu and Ph derivatives respectively, indicating the pentacoordinate geometry for fin atoms. In solid state, for methyl derivatives (1c, 1d) a distorted octahedral geometry for fin atoms was observed owing the presence of Sn center dot center dot center dot O intermolecular interactions.
• Golodnyuk, T. I.; Vinogradova, V. I., Russian Journal of Organic Chemistry, 1995, vol. 31, # 3, p. 435
  作者：Golodnyuk, T. I.、Vinogradova, V. I.

  DOI：——

  日期：——
• [EN] BISPHENOLS IN CANCER THERAPY<br/>[FR] BISPHÉNOLS UTILISÉS DANS LE TRAITEMENT DU CANCER
  申请人：UNIV MANITOBA

  公开号：WO2009072002A2

  公开（公告）日：2009-06-11

  The present invention generally relates to anticancer agents and methods of treating cancer. The anticancer agents described herein comprise a bisphenol core and generally act as topoisomerase II inhibitors, though their anticancer activity may be related to other mechanisms as well. The bisphenols discussed therein may also protect certain cells against detrimental effects of topoisomerase II poisons.
• Allakhverdiev; Babai; Farzaliev, Petroleum Chemistry, 2001, vol. 41, # 2, p. 135 - 139
  作者：Allakhverdiev、Babai、Farzaliev、Aliev、Rzaeva、Khalilova

  DOI：——

  日期：——
• Golodnyuk, T.I.; Vinogradova, V.I., Russian Journal of Organic Chemistry, 1993, vol. 29, # 9, p. 1593
  作者：Golodnyuk, T.I.、Vinogradova, V.I.

  DOI：——

  日期：——