2,8,14,20-tetra-p-tolyl-4,6,10,12,16,18,22,24-octahydroxycalix-[4]-resorcarene | 181231-11-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 2,8,14,20-tetra-p-tolyl-4,6,10,12,16,18,22,24-octahydroxycalix-[4]-resorcarene
• 英文别名: 2,8,14,20-Tetrakis(4-methylphenyl)pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaene-4,6,10,12,16,18,22,24-octol
• CAS: 181231-11-8
• 化学式: C₅₆H₄₈O₈
• 分子量: 848.992
• InChiKey: GDNYSCABAQXABL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.1
• 重原子数：
  64
• 可旋转键数：
  4
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  162
• 氢给体数：
  8
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  4'-[4-(溴甲基)苯基]-2,2':6',2''-三联吡啶 、 2,8,14,20-tetra-p-tolyl-4,6,10,12,16,18,22,24-octahydroxycalix-[4]-resorcarene 在 caesium carbonate 作用下， 以 乙腈 为溶剂， 反应 37.0h， 以69%的产率得到2,8,14,20-tetra-p-tolyl-4,6,10,12,16,18,22,24-octahydroxycalix-[4]-resorcarene
  参考文献：
  名称：

  一系列新的甲苯基吡啶并附有杯芳烃的八核钌（ii）配合物的合成，发光和电化学研究†

  摘要：

  一系列新的甲苯并吡啶的杯核Ru（II）络合物附加杯芳烃[[Ru（ttpy）} 8（L1）]（PF 6）16（4），[{Ru（ttpy）} 8（L2）]（PF 6）16（5）和[{Ru（ttpy）} 8（L3）]（PF 6）16（6）[ L1 = 2,8,14,20-四乙基-4,6,10,12,16， 18,22,24-八（4'-对-苄氧基-（2,2'：6'，2''-叔吡啶基））杯[4]间苯二酚；L2= 2,8,14,20-四苯基-4,6,10,12,16,18,22,24-八（4'-对-苄氧基-（2,2'：6'，2''-叔吡啶基））calix [4]间苯二酚；并且L3 = 2,8,14,20-四-对甲苯基-4,6,10,12,16,18,22,24-八（4'-对-苄氧基-（2,2'：6' ，2''-terpyridinyl））杯[4]间苯二酚]已经合成并表征。四乙基，四苯基和四对甲苯基邻苯

  DOI：

  10.1039/c5dt02363g
• 作为产物：
  描述：

  对甲基苯甲醛 、 间苯二酚 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 12.0h， 以87%的产率得到2,8,14,20-tetra-p-tolyl-4,6,10,12,16,18,22,24-octahydroxycalix-[4]-resorcarene
  参考文献：
  名称：

  对称取代间苯二酚[4]芳烃的结构构象异构体

  摘要：

  摘要 通过典型的一锅酸催化反应合成了C2h和C4v对称椅冠构象异构体中的甲基间苯二酚[4]芳烃和C2v对称舟形构象中的间苯二酚[4]芳烃，并对其进行了结构表征。椅子和船形异构体结晶状态的有机分子的溶剂化显示了间苯二酚 [4] 芳烃之间的相互作用通过涉及溶剂化物分子的分子间氢键保持在一起。分子内氢键自然形成于取代间苯二酚[4]芳烃的冠异构体中。

  DOI：

  10.1016/j.molstruc.2003.08.004

文献信息

• Yttrium(III) Nitrate: A Powerful Catalyst for Green and Rapid Synthesis of Some Supramolecules
  作者：Afsaneh Arami、Bahador Karami、Saeed Khodabakhshi

  DOI：10.1002/jccs.201400141

  日期：2015.1

  A convenient and rapid procedure for the synthesis of calix[4]resorcinarenes as useful supramolecules has been developed via a reaction of aryl aldehydes with resorcinol in the presence of yttrium(III) nitrate under solvent‐free conditions. This eco‐friendly method has many appealing attributes such as excellent yields, short reactions times, and simple work‐up procedures.

  在无溶剂条件下，通过芳基醛与间苯二酚在硝酸钇（III）的存在下反应，已经开发出一种便捷，快速的合成杯[4]间苯二碳氢化合物作为有用的超分子的方法。这种生态友好的方法具有许多吸引人的属性，例如出色的收率，较短的反应时间和简单的后处理程序。
• Synthesis of calixresorcarenes using magnetic poly triazine-benzene sulfonamide-SO₃H
  作者：Alireza Gharehkhani、Ramin Ghorbani-vaghei、Sedigheh Alavinia

  DOI：10.1039/d1ra07393a

  日期：——

  catalyst was also investigated in the synthesis of novel calixresorcarene derivatives. The advantages of heterogeneous nature, catalytic activity and the recyclability of the polymer support were also strengthened by advanced surface treatment. These key factors (basic sites, acidic sites and heterogeneity) play essential roles in the catalyst performance. This procedure has some advantages such as short

  这项工作的目的是开发一种可磁性回收的固定化碱催化剂，用于绿色合成杯间苯二酚。为此，将聚三嗪-苯磺酰胺 (PTBSA) 包覆在磁性 Fe3O4 纳米颗粒上，随后负载氯磺酸以获得 Fe3O4@PTBSA-SO3H。采用TEM、XRD、FT-IR、VSM、WDX、EDX、TGA/DSC和FE-SEM对纳米Fe3O4@PTBSA-SO3H的结构进行了表征。该催化剂的催化效率也在新型杯间苯二酚衍生物的合成中进行了研究。通过先进的表面处理，聚合物载体的非均相性、催化活性和可回收性的优势也得到了加强。这些关键因素（碱性位点、酸性位点和多相性）在催化剂性能中起着至关重要的作用。
• RESIST COMPOSITION
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：EP3007004A1

  公开（公告）日：2016-04-13

  The resist composition according to the present invention is a resist composition comprising a solid component comprising a resist base material, and a solvent. In the resist composition according to the present invention, the resist composition contains 1 to 80% by mass of the solid component and 20 to 99% by mass of the solvent, the resist base material comprises a compound (ctt form) represented by a predetermined formula (1) and a compound represented by a predetermined formula (3), the proportion of the compound (ctt form) represented by the predetermined formula (1) to the resist base material is from 65 to 99% by mass, and the mass ratio of the compound represented by the predetermined formula (3) to the compound (ctt form) represented by the predetermined formula (1) is from 0.01 to 0.53.

  根据本发明的抗蚀剂组合物是一种抗蚀剂组合物，包括由抗蚀剂基材组成的固体成分和溶剂。在根据本发明的抗蚀剂组合物中，抗蚀剂组合物含有 1% 至 80% （按质量计）的固体成分和 20% 至 99% （按质量计）的溶剂，抗蚀剂基础材料包括由预定式（1）表示的化合物（ctt 形式）和由预定式（3）表示的化合物、预定式（1）所代表的化合物（ctt 形式）占抗蚀剂基础材料的质量比例为 65% 至 99%，预定式（3）所代表的化合物与预定式（1）所代表的化合物（ctt 形式）的质量比为 0.01 至 0.53。
• Calix[4]resorcinols functionalized with amino acid residues
  作者：N. I. Shatalova、E. L. Gavrilova、N. A. Sidorov、A. R. Burilovb、M. A. Pudovik、E. A. Krasil’nikova、A. I. Konovalov

  DOI：10.1134/s1070363209070159

  日期：2009.7

  By the Mannich reaction in ternary systems calix[4]resorcinol-amino acid (amino acid ester, amino lid ester hydrochloride)-formaldehyde calix[4]resorcinols were obtained functionalized on the upper molecule rim by amino acid residues.
• Host-guest chemistry. 27. Mechanisms of macrocycle genesis. The condensation of resorcinol with aldehydes
  作者：Frank Weinelt、Hans Joerg Schneider

  DOI：10.1021/jo00019a011

  日期：1991.9

  The title reactions proceed in high yields without high dilution techniques as long as substituents allow hydrogen bonds between the phenolic units and do not lead to steric hindrance. Isomerization rates for three epimeric cyclophanes, including a hitherto undiscovered one, are obtained by least-squares fit with integrated rate equations. The buildup sequences of oligomers, polymers, and macrocycles are analyzed by numerical stepwise integration with 50 rate constants, based on the fit of time-concentration curves of seven identified structures that were followed by proton NMR. Macrocyclization is favored by the following: (a) fast degradation of oligomers, (b) fast ring closure of tetramers, as well as (c) fast chain growth to these in comparison to ring opening. Homogeneous reaction conditions, here with methanol as solvent, are essential not only for the quantitative analyses, but also for the solubility of polymers in view of their degradation and for the observation of new stereoisomers. Molecular mechanics calculations with the CHARMm field and model considerations identify the factors responsible for the unique preference for cyclization over polymerization. Both hydrogen bonds between the phenolic units and 1.5 interactions between phenolic groups and the methyl substituent-stemming from the acetaldehyde-strongly favor folded conformers with small distances around d = 3.3-4.6 angstrom between the terminal reacting centers in comparison to stretched conformations with d = 12.2-18.3 angstrom.