| 1470074-10-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• CAS: 1470074-10-2
• 化学式: C₄₄H₅₆O₂₂
• 分子量: 936.915
• InChiKey: GYTDBJGJUHCCGG-UEOHHWHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.87
• 重原子数：
  66.0
• 可旋转键数：
  13.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  284.62
• 氢给体数：
  1.0
• 氢受体数：
  22.0

反应信息

• 作为反应物：
  描述：

  在 水 、 potassium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以29 mg的产率得到zearalenone-14-β-D-gentiobioside
  参考文献：
  名称：

  Gentiobiosylation of β-Resorcylic Acid Esters and Lactones: First Synthesis and Characterization of Zearalenone-14-β,d-Gentiobioside

  摘要：

  The development of an optimized protocol for the gentiobiosylation of beta-resorcylic acid esters and lactones (beta-RAL) is presented. Different gentiobiosyl donors were prepared and used for regioselective and diastereoselective glycosylation affording a reliable synthetic strategy towards this class of natural product glycosides. The improved procedure was finally used for the preparation of the masked Fusarium mycotoxin zearalenone-14-beta,D-gentiobioside.

  DOI：

  10.1055/s-0033-1339338
• 作为产物：
  描述：

  beta-龙胆二糖八乙酸酯 在 乙酰溴 、 四丁基溴化铵 、 溶剂黄146 、 sodium hydroxide 作用下， 以 甲醇 、 氯仿 、 水 为溶剂， 反应 10.0h， 生成
  参考文献：
  名称：

  Gentiobiosylation of β-Resorcylic Acid Esters and Lactones: First Synthesis and Characterization of Zearalenone-14-β,d-Gentiobioside

  摘要：

  The development of an optimized protocol for the gentiobiosylation of beta-resorcylic acid esters and lactones (beta-RAL) is presented. Different gentiobiosyl donors were prepared and used for regioselective and diastereoselective glycosylation affording a reliable synthetic strategy towards this class of natural product glycosides. The improved procedure was finally used for the preparation of the masked Fusarium mycotoxin zearalenone-14-beta,D-gentiobioside.

  DOI：

  10.1055/s-0033-1339338