己二酸-双-2-(二甲氨基)乙酯 | 65169-69-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 己二酸-双-2-(二甲氨基)乙酯
• 英文名称: Adipinsaeure-bis-<2-dimethylamino-ethylester>
• 英文别名: adipic acid bis-(2-dimethylamino-ethyl ester)；Adipinsaeure-bis-(2-dimethylamino-aethylester)；bis[2-(dimethylamino)ethyl] adipate；Bis(2-(dimethylamino)ethyl) adipate；bis[2-(dimethylamino)ethyl] hexanedioate
• CAS: 65169-69-9
• 化学式: C₁₄H₂₈N₂O₄
• 分子量: 288.387
• InChiKey: LQIWJZRUBHDHFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  20
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• 海关编码：
  2922499990

反应信息

• 作为反应物：
  描述：

  己二酸-双-2-(二甲氨基)乙酯 、 溴代十二烷 以 丙酮 为溶剂， 反应 24.0h， 以91.6%的产率得到
  参考文献：
  名称：

  Phase-transfer catalysis of a new cationic gemini surfactant with ester groups for nucleophilic substitution reaction

  摘要：

  A highly effective phase transfer of a quaternary ammonium gemini surfactant with ester groups ((diethylhexanedioate) diyl-alpha,omega-bis(dimethyl dodecyl ammonium bromide) referred to as 12-10-12) was synthesized with high yield and characterized by infrared spectroscopy, elemental analysis and H-1-NMR. Then, 12-10-12 was used as a phase transfer catalyst to study the catalytic effect on the reaction of anhydrous sodium acetate and 4-methylbenzyl chloride. The possible catalytic mechanism and the influence of surfactant concentration, temperature and type are also discussed. The experimental results showed that the catalysis efficiency was more active than the traditional, single-chained surfactant, tetrabutyl ammonium bromide. It also revealed that the reaction was first-order with respect to the concentration of 4-methylbenzyl chloride. The concentration of 4-methylbenzyl chloride grew linearly with the concentration of 12-10-12 and as the reaction temperature increased. The optimum reaction time was 7 h. (C) 2014 Zhong-Wen Pan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2014.04.006
• 作为产物：
  描述：

  N,N-二甲基乙醇胺 、 己二酸二甲酯 在 二月桂酸二丁基锡 作用下， 反应 6.0h， 以62.5%的产率得到己二酸-双-2-(二甲氨基)乙酯
  参考文献：
  名称：

  新型合成双子表面活性剂作为盐酸溶液中碳钢的缓蚀剂

  摘要：

  含季酯间隔，即（diethylhexanedioate）二基- α，ω -双铵双子表面活性剂（二甲基十四烷基溴化铵）（14-DEHA-14）使用用二甲基己二酸酯，二甲基氨基乙醇的两步方法合成，和1溴十四烷。该化合物的化学结构已通过红外（IR）光谱证实，1H核磁共振（NMR）和元素分析。通过电导率和张力测量法确定临界胶束浓度，并通过失重测量研究其对稀（1.0 M）盐酸溶液中碳钢腐蚀的抑制作用。结果表明，合成的双子表面活性剂在1.0 M HCl溶液中可作为优异的缓蚀剂。抑制剂通过化学吸附在碳钢表面上的吸附遵循Langmuir吸附等温线。结合计算出的热力学参数和吸附等温线，讨论了该化合物可能的腐蚀机理。

  DOI：

  10.1007/s11743-015-1740-4

文献信息

• SILANE-MODIFIED FORMAMIDES
  申请人：Covestro Deutschland AG

  公开号：US20160340372A1

  公开（公告）日：2016-11-24

  The invention relates to novel silane-modified formamide-polymers and/or pre-polymers for bonding and/or sealing diverse substrate materials, such as, for example metal, wood, glass and/or plastic. The invention also relates to a reactive single-component adhesive system comprising the claimed silane-modified formamide polymers.

  该发明涉及用于粘接和/或密封不同基材的新型硅烷改性甲酰胺聚合物和/或前聚物，例如金属、木材、玻璃和/或塑料。该发明还涉及一种包括所述硅烷改性甲酰胺聚合物的反应性单组分粘合系统。
• Inhibition of NADH oxidation by 1-methyl-4-phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds
  作者：Sergey O. Sablin、Matthew J. Krueger、Victoria L. Yankovskaya、Sergey E. Tkachenko、Alexander N. Razdolsky、Sergey O. Bachurin、Rona R. Ramsay、Thomas P. Singer

  DOI：10.1002/(sici)1522-7146(1996)11:1<33::aid-jbt5>3.0.co;2-w

  日期：——

  inhibitors than the corresponding MPP+ derivatives. The IC50 values for these compounds and previously published figures for MPP+ analogs were then used to select a computer model based on structural parameters to predict the inhibitory potency of other compounds that react at the "rotenone site" in Complex I. A series of 12 novel inhibitors different in structure from the basic set were used to test

  1-甲基-4-苯基吡啶鎓（MPP +）及其类似物抑制线粒体呼吸链的NADH脱氢酶（复合物I）导致多巴胺能细胞死亡。在本研究中，表征了N-甲基-噻唑类化合物（N-甲基-苯乙烯基吡啶鎓）的氧化产物对内膜制剂中线粒体呼吸和NADH氧化的抑制作用。发现这些非柔性MPP +类似物比相应的MPP +衍生物是更有效的抑制剂。这些化合物的IC50值和先前发布的MPP +类似物数据用于基于结构参数选择计算机模型，以预测在复合物I中“鱼藤酮位点”反应的其他化合物的抑制能力。一系列12种与基本结构不同的新型抑制剂被用于测试所选模型的预测能力。尽管新型测试化合物与基于该模型的MPP +和苯乙烯基吡啶鎓类似物之间存在重大结构差异，但在预测的IC50值和实验确定的IC50值之间发现了实质性的一致性。该技术的价值在于可以预测其他药物和毒素在鱼藤酮位点的相互作用来阻止线粒体呼吸的抑制能力。在预测的IC50值和实验确定的I
• Diol (meth) acrylate compound having urethane bond, method for producing the same, and polymer thereof
  申请人：Kang Eui-chul

  公开号：US20060089473A1

  公开（公告）日：2006-04-27

  The present invention provides compounds having in their molecule a structure contributing to high hydrophilicity, and having high photopolymerizability, as well as polymers of such compounds, and a method for producing the compound. The compounds are diol (meth)acrylate having a urethane bond represented by the formula (1), and cyclic ketal (meth)acrylate having a urethane bond represented by the formula (2): (R 1 : H, —CH 3 ; R 2 : —(CH 2 )n-; R 3 : —(CH 2 )m-; n: 1-4; m: 1-8; (AO) : C2-C4 oxyalkylene group; x: 0-1000; R 4 , R 5 : H, —CH 3 , —C 2 H 5 ).

  本发明提供了分子中具有有助于高亲水性的结构，并具有高光聚合性的化合物，以及这些化合物的聚合物，以及生产该化合物的方法。这些化合物是具有由式（1）表示的脲酯键的双醇（甲）丙烯酸酯，以及具有由式（2）表示的脲酯键的环戊二酮（甲）丙烯酸酯：（R1：H，—CH3；R2：—（CH2）n-；R3：—（CH2）m-；n：1-4；m：1-8；（AO）：C2-C4氧烷基；x：0-1000；R4，R5：H，—CH3，—C2H5）。
• ISOCYANATOSILANES WITH THIOURETHANE STRUCTURE
  申请人：Bayer MaterialScience AG

  公开号：US20150246936A1

  公开（公告）日：2015-09-03

  The invention relates to a method for producing compounds containing isocyanate and silane groups by reacting at least A) one monomeric diisocyanate containing aliphatically, cycloaliphatically, araliphatically and/or aromatically bonded isocyanate groups with B) a mercaptosilane, characterised in that component A) is reacted with component B) in an equivalent ratio of isocyanate groups to mercapto groups of at least 06:01 to at most 40:1. Furthermore, the invention relates to the products which can be obtained using the method according to the invention, and to a composition containing compounds that contain isocyanate and silane groups. Moreover, the invention relates to the use of the products which can be obtained using the method according to the invention and the composition according to the invention as starting components in the production of silane group-containing polyurethanes, cross-linkable binders, varnish, and raw materials for sealants or adhesives.

  本发明涉及一种通过将至少A）一种含有脂肪族、环脂族、芳基脂肪族和/或芳香基结合的异氰酸酯基团的单体二异氰酸酯与B）巯基硅烷反应来生产含有异氰酸酯和硅烷基团的化合物的方法，其特征在于A）组分与B）组分以等当比例的异氰酸酯基团与巯基团反应，比例范围为至少06:01到最多40:1。此外，本发明涉及使用本发明方法可获得的产品，以及含有含有异氰酸酯和硅烷基团的化合物的组合物。此外，本发明还涉及使用本发明方法和组合物所得产品作为含硅烷基的聚氨酯、可交联粘合剂、清漆和密封剂或粘合剂的原材料的用途。
• DIOL (METH) ACRYLATE COMPOUND HAVING URETHANE BOND, METHOD FOR PRODUCING THE SAME, AND POLYMER THEREOF
  申请人：Kang Eui-chul

  公开号：US20090240015A1

  公开（公告）日：2009-09-24

  The present invention provides compounds having in their molecule a structure contributing to high hydrophilicity, and having high photopolymerizability, as well as polymers of such compounds, and a method for producing the compound. The compounds are diol (meth)acrylate having a urethane bond represented by the formula (1), and cyclic ketal (meth)acrylate having a urethane bond represented by the formula (2): (R 1 : H, —CH 3 ; R 2 : —(CH 2 )n-; R 3 : —(CH 2 )m-; n: 1-4; m: 1-8; (AO): C2-C4 oxyalkylene group; x: 0-1000; R 4 , R 5 : H, —CH 3 , —C 2 H 5 ).

  本发明提供了一种分子中具有高亲水性结构并具有高光聚合性的化合物，以及这些化合物的聚合物和制备这些化合物的方法。该化合物是具有尿素键的二元醇（甲基）丙烯酸酯，其化学式表示为（1），以及具有尿素键的环状酮（甲基）丙烯酸酯，其化学式表示为（2）：（R1：H，—CH3；R2：—（CH2）n-；R3：—（CH2）m-；n：1-4；m：1-8；（AO）：C2-C4氧烷基；x：0-1000；R4，R5：H，—CH3，—C2H5）。