A semisynthesis of isepamicin by fragmentation method
摘要:
Garamine derivative, key intermediate, was obtained from acid cleavage of sisomicin derivative. Its subsequent product was glycosylated with 6-azido-2,3,4-tri-O-benzyl-6-deoxy-alpha-D-glucopyranosyl chloride using silver triflate as a promoter to give isepamicin. (C) 2004 Elsevier Ltd. All rights reserved.
A semisynthesis of isepamicin by fragmentation method
摘要:
Garamine derivative, key intermediate, was obtained from acid cleavage of sisomicin derivative. Its subsequent product was glycosylated with 6-azido-2,3,4-tri-O-benzyl-6-deoxy-alpha-D-glucopyranosyl chloride using silver triflate as a promoter to give isepamicin. (C) 2004 Elsevier Ltd. All rights reserved.