(2E,4E,7Z)-2,4,7-decatrien-1-ol | 157462-02-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2E,4E,7Z)-2,4,7-decatrien-1-ol
• 英文别名: deca-2t,4c,7c-trien-1-ol；(2E,4Z,7Z)-deca-2,4,7-trien-1-ol
• CAS: 157462-02-7
• 化学式: C₁₀H₁₆O
• 分子量: 152.236
• InChiKey: LXIWSTYXFPXANW-OORNVTMFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (2E,4E,7Z)-2,4,7-decatrien-1-ol 在 N-氯代丁二酰亚胺 、 二甲基硫 作用下， 生成 (2E,4Z,7Z)-1-Chloro-deca-2,4,7-triene
  参考文献：
  名称：

  Didemnilactones A and B and neodidemnilactone three new fatty acid metabolites isolated from the tunicate Didemnum moseleyi (Herdman)

  摘要：

  Three new fatty acid metabolites didemnilactones A (1) and B (2) and neodidemnilactone (3) were isolated from the tunicate Didemnum moseleyi (Herdman). Their structures including absolute stereochemistry were established on the basis of spectral studies and chemical synthesis. Didemnilactones exhibited inhibitory activity against lipoxygenase and weak binding activity to leukotriene B-4 receptors.

  DOI：

  10.1016/s0040-4020(01)90469-7
• 作为产物：
  描述：

  顺式-4-庚烯醛 在 四(三苯基膦)钯 、 2,6-二叔丁基-4-甲基吡啶 、 lithium chloride 作用下， 以 四氢呋喃 、 1,2-二氯乙烷 为溶剂， 反应 5.0h， 生成 (2E,4E,7Z)-2,4,7-decatrien-1-ol
  参考文献：
  名称：

  Didemnilactones A and B and neodidemnilactone three new fatty acid metabolites isolated from the tunicate Didemnum moseleyi (Herdman)

  摘要：

  Three new fatty acid metabolites didemnilactones A (1) and B (2) and neodidemnilactone (3) were isolated from the tunicate Didemnum moseleyi (Herdman). Their structures including absolute stereochemistry were established on the basis of spectral studies and chemical synthesis. Didemnilactones exhibited inhibitory activity against lipoxygenase and weak binding activity to leukotriene B-4 receptors.

  DOI：

  10.1016/s0040-4020(01)90469-7

文献信息

• A PROCESS FOR THE OXIDATION OF UNSATURATED ALCOHOLS
  申请人：Firmenich SA

  公开号：EP1472207A1

  公开（公告）日：2004-11-03
• US6995291B2
  申请人：——

  公开号：US6995291B2

  公开（公告）日：2006-02-07
• [EN] A PROCESS FOR THE OXIDATION OF UNSATURATED ALCOHOLS<br/>[FR] PROCESSUS D'OXYDATION D'ALCOOLS INSATURES
  申请人：FIRMENICH & CIE

  公开号：WO2003064362A1

  公开（公告）日：2003-08-07

  The present invention relates to the field of organic synthesis and more precisely to a process for the synthesis of an unsaturated aldehyde or ketone by oxidation of the corresponding alcohol. Said oxidation is characterized in that it is performed by means of a hypochlorite salt and a catalytic amount of a N-(2,2,6,6-tetraalkyl-4-piperidinyl-N-oxyl)-2-amino-1,3,5-triazine derivative, preferably a N-oxyl derivative of the polymers known under the trademark Chimassorb® 944 or 2020.
• Didemnilactones A and B and neodidemnilactone three new fatty acid metabolites isolated from the tunicate Didemnum moseleyi (Herdman)
  作者：Haruki Niwa、Masaru Watanabe、Hideaki Inagaki、Kiyoyuki Yamada

  DOI：10.1016/s0040-4020(01)90469-7

  日期：——

  Three new fatty acid metabolites didemnilactones A (1) and B (2) and neodidemnilactone (3) were isolated from the tunicate Didemnum moseleyi (Herdman). Their structures including absolute stereochemistry were established on the basis of spectral studies and chemical synthesis. Didemnilactones exhibited inhibitory activity against lipoxygenase and weak binding activity to leukotriene B-4 receptors.