2-phenyl-2,2'-bi-1,3-dioxolane | 21504-04-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-phenyl-2,2'-bi-1,3-dioxolane
• 英文别名: 2-Phenyl-[2,2']bi[1,3]dioxolanyl；2,2'-Bi-1,3-dioxolane, 2-phenyl-；2-(1,3-dioxolan-2-yl)-2-phenyl-1,3-dioxolane
• CAS: 21504-04-1
• 化学式: C₁₂H₁₄O₄
• 分子量: 222.241
• InChiKey: QFPMHHPGZMFVMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  苯基丙醇水合物 、 乙二醇 在 硫酸 作用下， 生成 2-phenyl-2,2'-bi-1,3-dioxolane
  参考文献：
  名称：

  Boeeseken; Tellegen, Recueil des Travaux Chimiques des Pays-Bas, 1938, vol. 57, p. 133,141

  摘要：

  DOI：

文献信息

• Methods related to volatile compounds in genitourinary cancers
  申请人：Lee Wen-Yee

  公开号：US10908162B2

  公开（公告）日：2021-02-02

  Embodiments are directed to methods of identifying a subject having prostate cancer or renal cell carcinoma; or prostate cancer risk assessment of a subject by determining level of at least one volatile organic compound from a sample from the subject where a significantly different level of the at least one volatile organic compound in the sample as compared to the level of the compound in a control sample is indicative of the presence of prostate cancer or renal cell carcinoma or low-risk prostate cancer or high-low prostate cancer in the subject.

  本发明的实施方案涉及识别患有前列腺癌或肾细胞癌的受试者的方法；或通过确定受试者样本中至少一种挥发性有机化合物的水平来评估受试者的前列腺癌风险的方法，其中样本中至少一种挥发性有机化合物的水平与对照样本中该化合物的水平相比存在显著差异，则表明受试者存在前列腺癌或肾细胞癌或低风险前列腺癌或高风险前列腺癌。
• Selenium-mediated conversion of alkynes into .alpha.-dicarbonyl compounds
  作者：Marcello Tiecco、Lorenzo Testaferri、Marco Tingoli、Donatella Chianelli、Donatella Bartoli

  DOI：10.1021/jo00014a038

  日期：1991.7

  The reaction of terminal and internal alkynes with diphenyl diselenide and ammonium peroxydisulfate in methanol proceeds smoothly to give alpha-keto acetals and alpha-keto ketals, respectively. This one-pot procedure is suggested to proceed through the initial formation of phenylselenenyl sulfate, a strong electrophilic reagent which effects the methoxyselenenylation of the alkynes. The addition products thus formed suffer methoxydeselenenylation giving the observed products and regenerating the phenylselenenylating agent. In some cases the reaction can be carried out using only catalytic amounts of diphenyl diselenide. The same reaction carried out in the presence of water or of ethylene glycol gives the unprotected or the diprotected alpha-dicarbonyl compounds, respectively.
• METHODS RELATED TO VOLATILE COMPOUNDS IN GENITOURINARY CANCERS
  申请人：Lee Wen-Yee

  公开号：US20190128890A1

  公开（公告）日：2019-05-02

  Embodiments are directed to methods of identifying a subject having prostate cancer or renal cell carcinoma; or prostate cancer risk assessment of a subject by determining level of at least one volatile organic compound from a sample from the subject where a significantly different level of the at least one volatile organic compound in the sample as compared to the level of the compound in a control sample is indicative of the presence of prostate cancer or renal cell carcinoma or low-risk prostate cancer or high-low prostate cancer in the subject.