(4S)-5-methoxy-4-methylpentan-1-amine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4S)-5-methoxy-4-methylpentan-1-amine
• 化学式: C₇H₁₇NO
• 分子量: 131.22
• InChiKey: WMDAGYAUERCPLQ-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS
  申请人：IONIS PHARMACEUTICALS, INC.

  公开号：US20170043025A1

  公开（公告）日：2017-02-16

  Provided herein are improved methods for the synthesis of reactive conjugate clusters and intermediates used in such methods. In particular, improvements are provided that enhance the synthesis of reactive conjugate clusters by reducing the number of synthetic steps required. The reactive conjugate clusters prepared using the improved methods don't include any transacylation impurities that are formed using existing methods. The improved methods also provide an increase in overall yield and a cost benefit over existing methods.