[(2S,3S,5S)-4,5-diphosphonooxy-6-(phosphonooxymethyl)-2-[(3R,4S,6S)-4,5,6-triphosphonooxy-2-(phosphonooxymethyl)oxan-3-yl]oxyoxan-3-yl] dihydrogen phosphate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2S,3S,5S)-4,5-diphosphonooxy-6-(phosphonooxymethyl)-2-[(3R,4S,6S)-4,5,6-triphosphonooxy-2-(phosphonooxymethyl)oxan-3-yl]oxyoxan-3-yl] dihydrogen phosphate
• 化学式: C₁₂H₃₀O₃₅P₈
• 分子量: 982.1
• InChiKey: BGRANQAJNQESIA-SMIZIPLESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -14
• 重原子数：
  55
• 可旋转键数：
  20
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  562
• 氢给体数：
  16
• 氢受体数：
  35

文献信息

• POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES
  申请人：Lehn Jean-Marie

  公开号：US20140155334A1

  公开（公告）日：2014-06-05

  The present invention provides, among other things, phosphorylated and pyrophosphate derivatives of mono-, di- and oligosaccharides, as well as structural derivatives of these compounds. These compounds have a variety of uses including for pharmaceutical applications. Also provided are methods of use in the treatment of disease, including diseases related to oxygen delivery.

  本发明提供了单糖，二糖和寡糖的磷酸化和焦磷酸酯衍生物，以及这些化合物的结构衍生物，其中这些化合物具有各种用途，包括用于制药应用。此外，还提供了在治疗疾病中使用的方法，包括与氧输送相关的疾病。